Results 121 to 130 of about 489,119 (312)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Open letter: Six steps towards a national plan of protected horticulture—A call for coordinated action

Plants, People, Planet
The UK's growing reliance on imports and rising climate risks highlight the need to expand protected horticulture as a secure, low‐carbon source of fruit and vegetables.
Sven Batke, David Barker, Darrell Jones, Jack Farmer, Noel O'Leary, Phil Morley, John Walgate, Lee Stiles, Luke Hibberd, Jason Perrott, Alfie Russell, Ralph Weir, Nathanael Dannenberg, Robert Woods, Oliver Green, Stuart Gibson, Laura Pearson, Stephanie Tarvin, David Rowley, Bethan Mcilroy, Su Varma, Paul Rutten, Joe Shepherdson, Kathryn Fletcher, Anthony Paul Sangwine, Helen Sessions, Toni Borella, Samuel Harris, Nathan Thomas, Charlie Guy, Ruth Vichos, Esther deBeer   +31 more
doaj   +1 more source

Global safety of fresh produce : a handbook of best practice, innovative commercial solutions and case studies /

Recent food poisoning outbreaks such as the European case of E. coli in sprouts in 2011 have meant that fresh produce safety is very much at the forefront of food research.
Hoorfar, J.,editor.
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Assessing Consumer Preferences for Organically Grown Fresh Fruit and Vegetables in Eastern New Brunswick

consumer preferences, organic fresh produce, willingness-to-pay, Consumer/Household Economics, Crop Production/Industries, Demand and Price Analysis, Q1,
Hobbs, Jill E., Haghiri, Morteza, McNamara, Meaghan L.   +2 more
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

U.S. Fresh Fruit and Vegetable Marketing: Emerging Trade Practices, Trends, and Issues

In the past year, trade practices between fresh produce shippers and food retailers gained national attention. Shippers are concerned that recent retail consolidation has led to market power and the growing incidence of fees and services. Retailers argue
Cook, Roberta L., Thornsbury, Suzanne, Glaser, Lewrene K., Thompson, Gary D., Dimitri, Carolyn, Handy, Charles R., Jekanowski, Mark D., Denbaly, Mark, Calvin, Linda, Kaufman, Phillip R., Krissoff, Barry   +10 more
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Editorial: Breeding Crops for Enhanced Food Safety

Frontiers in Microbiology, 2022
Maeli Melotto, Wei Zhang, Max Teplitski
doaj   +1 more source

USING USDA FRESH FRUIT AND VEGETABLE ARRIVALS TO DETERMINE THE DISTRIBUTION OF A STATE'S PRODUCTION

This paper examines the problem of transforming information on fresh fruit and vegetable Arrivals to U.S. Metropolitan Statistical Areas into a distribution of products to larger geographical regions.
Portier, Kenneth M., Beilock, Richard
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