Results 71 to 80 of about 489,119 (312)

Enhancing Bromelain Recovery from Pineapple By-Products: A Sustainable Approach for Value Addition and Waste Reduction

Foods
Pineapple by-products are good sources of bromelain, a complex enzyme with commercial applications. This study evaluated the feasibility of producing bromelain powders from pineapple waste using an organic solvent-free approach.
Peter G. Chiarelli, Bismarck Martinez, Takashi Nakamura, Kevin Mis Solval   +3 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Microbiota asociada al cultivo de banano en Costa Rica y otras regiones: conceptos e implicaciones en el manejo del cultivo

Agronomía Costarricense
Introducción. La microbiota es un conjunto diverso de microorganismos que, al asociarse con las plantas, aporta beneficios clave, como la supresión de enfermedades, la tolerancia al estrés abiótico y la mejora en la adquisición de nutrientes.
Jose Pablo Vargas-Fernández, Laura Brenes-Guillén, Ronald Romero-Calderón, Lidieth Uribe-Lorío, Lorena Uribe-Lorío   +4 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Recent Advances in Reducing Food Losses in the Supply Chain of Fresh Agricultural Produce

, 2020
Fruits and vegetables are highly nutritious agricultural produce with tremendous human health benefits. They are also highly perishable and as such are easily susceptible to spoilage, leading to a reduction in quality attributes and induced food loss ...
Guangnan Chen, Abraham Kabutey, Onwude, Daniel I., Eke-emezie, Nnanna, Alfadhl Yahya Khaled, Nnanna Eke-emezie, Khaled, Alfadhl Yahya, Al Khaled, Al Fadhl Yahya, Sturm, Barbara, Chen, Guangnan, Barbara Sturm, Kabutey, Abraham, Daniel I. Onwude   +12 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Evaluation of Bacteriological Profile of the Fresh Produce in Beheira Governorate, Egypt

, 2017
The consumption of fresh produce has increased significantly in the recent decades. So far, no data are available on the bacteriological burden and the prevalence of foodborne pathogens in fresh produce of Beheira Governorate.
Moustafa El-Naggar, Ahmed Abdel-Mawgood, Zakia A. Olama, Zakia Olama, Abdelatty Saleh, Abdelatty M. Saleh, Moustafa Y. El-Naggar, Ahmed L. Abdel-Mawgood   +7 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source