Results 91 to 100 of about 489,119 (312)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Postharvest Practices for Organically Grown Products

open access: yesContemporary Agriculture, 2018
Quality of produce cannot be improved after harvest, only maintained. Postharvest handling depends on the specific conditions of production, season, method of handling, and distance to market.
Ilić Zoran S.   +4 more
doaj   +1 more source

Outbreaks Associated with Fresh Produce: Incidence, Growth, and Survival of Pathogens in Fresh and Fresh‐Cut Produce [PDF]

open access: yesComprehensive Reviews in Food Science and Food Safety, 2003
L.J. Harris   +6 more
openaire   +1 more source

Channel Management and differentiation strategies: A case study from the market for fresh produce

open access: yes
The paper analyses the current differentiation strategies in the market for fresh produce. First a short review of the literature on channel structure and product differentiation is presented, in order to identify, on a theoretical grounding the ...
Sodano, Valeria, Hingley, Martin
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Fresh Grapefruit Supply-Chain Adjustments: Consolidation in Produce Packing?

open access: yes
This study evaluates long-term structural adjustments in fresh grapefruit packing under aggregate market pressures, including those from retail concentration.
Thornsbury, Suzanne   +2 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

U.S. Fresh Produce Wholesale Sector Trade Practices: Initial Survey Results

open access: yes
The wholesale sector is an intermediate stage in the supply chain of fresh produce. In general, business operations in this sector do not transform a specific product, but rather provide services related to the sale of the product.
Thornsbury, Suzanne   +1 more
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

CONSUMER FOOD SAFETY CONCERNS AND FRESH PRODUCE CONSUMPTION

open access: yes
The linear approximation of an almost ideal demand system model was used to measure the impacts of prices, expenditures, and consumer food safety concerns on the consumption of 14 major fresh produce categories in the United States for the period 1970-92.
Henneberry, Shida Rastegari   +2 more
core  

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