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Results 61 to 70 of about 5,886 (212)

Genome‐Wide Assessment Reveals Ancestral Differences in Homozygosity Patterns Potentially Linked to Parkinson's Disease Etiology

Movement Disorders, Volume 41, Issue 5, Page 1128-1140, May 2026.
Abstract Background Recessive genetic variation and extended runs of homozygosity (ROHs) may contribute to the unexplained heritability of Parkinson's disease (PD), particularly in diverse and understudied populations. Objective We conducted the first large‐scale, multi‐ancestral investigation of PD to examine the impact of genome‐wide homozygosity on ...
Kathryn Step +680 more
wiley +1 more source

„Lasst uns froh und bunter sein“ – Interkulturelles Lernen im Religionsunterricht am Beispiel der besonderen Weihnachtsgeschichte des Herrn Schmidt

, 2023
Lerke S, Scholz M. „Lasst uns froh und bunter sein“ – Interkulturelles Lernen im Religionsunterricht am Beispiel der besonderen Weihnachtsgeschichte des Herrn Schmidt. In: Janus R, ed.
Lerke, Stephanie, Scholz, Marcel, Janus, Richard +2 more
core

Synteny Enabled Upgrade of the Galapagos Giant Tortoise Genome Improves Inferences of Runs of Homozygosity

Ecology and Evolution
The utility and importance of whole‐genome sequences are recognized across various fields, including evolution and conservation. However, for some taxa, like extinct species, using methods to generate contiguous genomes that rely on high‐quality DNA is ...
Evelyn L. Jensen +7 more
doaj +1 more source

Comparative genome-wide analysis of Ovis aries in Saudi Arabia highlighting inbreeding and genetic isolation of the Najdi sheep breed

Frontiers in Genetics
IntroductionSheep (Ovis aries) farming through traditional practices plays a vital role in the socio-economic development of the Kingdom of Saudi Arabia (KSA). Genetic relationships among KSA sheep breeds remain poorly characterized.MethodsIn this study,
Abdulrahman K. Aldawish +9 more
doaj +1 more source

Population Genomics Reveals Genetic Diversity, Introgression, and Genetic Differentiation in Tianshan Mountains Western Honeybees (Apis mellifera)

Evolutionary Applications, Volume 19, Issue 5, May 2026.
ABSTRACT The Tianshan Mountains, which host two native subspecies of western honeybees, represent the easternmost natural distribution limit of Apis mellifera. The managed Xinjiang black honeybee (XJ), introduced a century ago and designated as a Chinese National Animal Genetic Resource, has expanded rapidly under anthropogenic management.
Gulinuer Tulaxi +10 more
wiley +1 more source

“From Concern to Caring: A Journey to understanding Biblical Charity”

, 2012
Dr.
Froh, Charles
core

[Evander B. Schley's 'Froh Heim' Estate, Far Hills, NJ]

, 1932
The mining industrialist Evander B. Schley built his estate Froh Heim circa 1923. This Spanish-style home was designed by architects Peabody, Wilson & Brown of New York. Additional alterations were made by architect F. Burrall Hoffman, Jr.
Richie, Robert Yarnall, 1908-1984
core +1 more source

Whole-genome sequencing reveals patterns of runs of homozygosity underlying genetic diversity and selection in domestic rabbits

BMC Genomics
Background Runs of homozygosity (ROH) are continuous segments of homozygous genotypes inherited from both parental lineages. These segments arise due to the transmission of identical haplotypes. The genome-wide patterns and hotspot regions of ROH provide
Xinxin Ping +6 more
doaj +1 more source

A peptide inhibitor of C-jun N-terminal kinase modulates hepatic damage and the inflammatory response after hemorrhagic shock and resuscitation

, 2008
Hemorrhage and resuscitation (H/R) leads to phosphorylation of mitogen-activated stress kinases, an event that is associated with organ damage. Recently, a specific, cell-penetrating, protease-resistant inhibitory peptide of the mitogen-activated protein
M. Lehnert +17 more
core +1 more source

Genome-Wide Characterization of Selection Signatures and Runs of Homozygosity in Ugandan Goat Breeds

Frontiers in Genetics, 2018
Both natural and artificial selection are among the main driving forces shaping genetic variation across the genome of livestock species. Selection typically leaves signatures in the genome, which are often characterized by high genetic differentiation ...
Robert B. Onzima +9 more
doaj +1 more source

runs of homozygosity
inbreeding
genomic inbreeding

inbreeding coefficient
autozygosity
homozygosity

genetic diversity
inbreeding depression
local breeds