Results 41 to 50 of about 4,306 (172)

Recent Consanguinity and Outbred Autozygosity Are Associated With Increased Risk of Late-Onset Alzheimer’s Disease

Frontiers in Genetics, 2021
Prior work in late-onset Alzheimer’s disease (LOAD) has resulted in discrepant findings as to whether recent consanguinity and outbred autozygosity are associated with LOAD risk.
Valerio Napolioni, Marzia A. Scelsi, Raiyan R. Khan, Andre Altmann, Michael D. Greicius   +4 more
doaj   +1 more source

Over‐Representation of Sperm‐Associated Deleterious Mutations Across Wild and Ex Situ Cheetah (Acinonyx jubatus) Populations

Molecular Ecology, Volume 35, Issue 16, August 2026.
ABSTRACT As purifying selection becomes less effective and inbreeding increases, small populations frequently develop an increased load of genome‐wide deleterious mutations. Reflecting this pattern, deleterious mutations in genes associated with fertility and immunity have previously been identified in the cheetah (Acinonyx jubatus), which has had a ...
Jessica A. Peers, Heather R. Sibley, Ellie E. Armstrong, Adrienne E. Crosier, Will J. Nash, Klaus‐Peter Koepfli, Wilfried Haerty   +6 more
wiley   +1 more source

Spatial inference of ancestor locations suggests northern refugia for canopy‐forming kelps in the Pacific Northwest

New Phytologist, Volume 251, Issue 4, Page 2248-2265, August 2026.
Population genetic structure in the Pacific Northwest for (a–c) Nereocystis and (d–f) Macrocystis. Summary Pockets of the formerly glaciated Pacific coastline of North America likely remained ice‐free throughout the Last Glacial Maximum (LGM). These areas may have served as refugia for terrestrial species, but less is known about their role in the ...
Jordan B. Bemmels, Kristy J. Kroeker, Stephen R. Palumbi, Rachael A. Bay, Kristen M. Gruenthal, Sandra C. Lindstrom, Matthew M. Osmond, Gregory L. Owens   +7 more
wiley   +1 more source

Improving the stability of discretization zeros with the Taylor method using a generalization of the fractional-order hold

International Journal of Applied Mathematics and Computer Science, 2014
Remarkable improvements in the stability properties of discrete system zeros may be achieved by using a new design of the fractional-order hold (FROH) circuit. This paper first analyzes asymptotic behaviors of the limiting zeros, as the sampling period T
Zeng Cheng, Liang Shan, Zhang Yuzhe, Zhong Jiaqi, Su Yingying   +4 more
doaj   +1 more source

Runs of Homozygosity and Quantitative Trait Locus/Association for Semen Parameters in Selected Chinese and South African Beef Cattle

Animals, 2022
In this study, runs of homozygosity (ROH) and quantitative trait locus/association (QTL) for semen parameters in selected Chinese and South African beef cattle breed were estimated.
Mamokoma Cathrine Modiba, Khathutshelo Agree Nephawe, Jun Wang, Nompilo Hlongwane, Khanyisile Hadebe, Wenfa Lu, Bohani Mtileni   +6 more
doaj   +1 more source

Large‐Scale Genomics Reveals Three‐Source Ancestry and Layered Adaptation to High Altitude in Tibetan Chickens

Advanced Science, Volume 13, Issue 42, 28 July 2026.
Whole‐genome analysis of 1,054 chickens reveals three ancestral sources (NWC, SYA, and SHF) with distinct temporal entry patterns into the Tibetan Plateau. Route‐specific selection scans, calibrated against a demographic null, suggest complementary functional enrichments—vascular homeostasis (NWC), calcium signaling and cardiac adaptation (SYA), and ...
Zongyi Zhao, Ruixue Nie, Hailu Fan, Tenzin Ngodroup, Li Zhu, Hongbin Pan, Bo Zhang, Hao Zhang   +7 more
wiley   +1 more source

Imputation in the Wild: Genome‐Wide Robustness and Fine‐Scale Limitations of Low‐Coverage Genomes in Endangered Species

Molecular Ecology Resources, Volume 26, Issue 5, July 2026.
ABSTRACT Low‐coverage whole‐genome sequencing (lcWGS) combined with genotype imputation is increasingly being used to generate large genomic datasets at reduced cost, offering a promising alternative for conservation genomics. Here, we use the Iberian lynx (Lynx pardinus), a species with extremely low genetic diversity, genetically differentiated ...
Lucía Mayor‐Fidalgo, Enrico Bazzicalupo, Laia Pérez‐Sorribes, Laura Soriano, José A. Godoy   +4 more
wiley   +1 more source

Genome-Wide Runs of Homozygosity Revealed Selection Signatures in Bos indicus

Frontiers in Genetics, 2020
Genome-wide runs of homozygosity (ROH) are suitable for understanding population history, calculating genomic inbreeding, deciphering genetic architecture of complex traits and diseases as well as identifying genes linked with agro-economic traits ...
S. P. Dixit, Sanjeev Singh, Indrajit Ganguly, Avnish Kumar Bhatia, Anurodh Sharma, N. Anand Kumar, Ajay Kumar Dang, S. Jayakumar   +7 more
doaj   +1 more source

Conservation Status of Two Italian Local Poultry Breeds: Faraona Camosciata and Oca Padovana

Animal Genetics, Volume 57, Issue 3, June 2026.
ABSTRACT The present study aimed to assess the conservation status and characterize the phenotypic and genomic diversity of two endangered Italian poultry genetic resources to guide their conservation plans. Blood samples and morphometric data were collected on 50 Faraona Camosciata (FAC, Numida meleagris) and 50 Oca Padovana (OPD, Anser anser) adult ...
Filippo Cendron, Enrico Bortoletto, Francesco Perini, Maristella Baruchello, Umberto Rosani, Emiliano Lasagna, Martino Cassandro, Mauro Penasa   +7 more
wiley   +1 more source

Assessing different metrics of pedigree and genomic inbreeding and inbreeding effect on growth, fertility, and feed efficiency traits in a closed-herd Nellore cattle population

BMC Genomics
Background The selection of individuals based on their predicted breeding values and mating of related individuals can increase the proportion of identical-by-descent alleles.
Ricardo D. Bem, Lorena F. Benfica, Delvan A. Silva, Eula R. Carrara, Luiz F. Brito, Henrique A. Mulim, Marcelo S. Borges, Joslaine N. S. G. Cyrillo, Roberta C. Canesin, Sarah F. M. Bonilha, Maria E. Z. Mercadante   +10 more
doaj   +1 more source