Results 31 to 40 of about 6,810 (206)

Reasons for the culling of cows depending on the level of homozygosity and genomic inbreeding of fathers

Аграрная наука Евро-Северо-Востока
The causes of cow mortality were studied depending on the level of homozygosity and genomic inbreeding of sires. Genomic data from 307 Holstein and Black-and-White bulls with 34,280 daughters were used.
I. S. Nedashkovsky, A. F. Konte, A. A. Sermyagin, D. N. Koltsov, V. V. Volkova   +4 more
doaj   +1 more source

Improving the Asymptotic Properties of Discrete System Zeros in Fractional-Order Hold Case

Journal of Applied Mathematics, 2013
Remarkable improvements in the asymptotic properties of discrete system zeros may be achieved by properly adjusted fractional-order hold (FROH) circuit.
Cheng Zeng, Shan Liang, Yingying Su
doaj   +1 more source

Genomic measures of inbreeding coefficients and genome-wide scan for runs of homozygosity islands in Iranian river buffalo, Bubalus bubalis

BMC Genetics, 2020
Background Consecutive homozygous fragments of a genome inherited by offspring from a common ancestor are known as runs of homozygosity (ROH). ROH can be used to calculate genomic inbreeding and to identify genomic regions that are potentially under ...
Seyed Mohammad Ghoreishifar, Hossein Moradi-Shahrbabak, Mohammad Hossein Fallahi, Ali Jalil Sarghale, Mohammad Moradi-Shahrbabak, Rostam Abdollahi-Arpanahi, Majid Khansefid   +6 more
doaj   +1 more source

Captive Breeding of the Chinese Alligator Reduces Inbreeding but Increases Genetic Load

Integrative Zoology, EarlyView.
Captive breeding of the Chinese alligator successfully reduced genomic inbreeding but increased the burden of deleterious mutations. Genomic analyses indicate that managing both genetic diversity and genetic load is essential for the long‐term conservation of this critically endangered species.
Yihang Fan, Tao Pan, Nicolas Dussex, Tianming Lan   +3 more
wiley   +1 more source

Genomic Diversity of the Endangered Guinan Toad‐Headed Lizard and Its Conservation Implications

Integrative Zoology, EarlyView.
We produced HiFi long reads and assembled a high‐quality genome for the Guinan toad‐headed lizard—Phrynocephalus guinanensis—and present a comprehensive conservation genomics assessment. Our findings clearly show population structure, a reduced genetic diversity pattern, and a strong bottleneck in demographic history, reaffirming the endangered status ...
Ying Chen, Song Tan, Yiru Wang, Xia Qiu, Da Kang, Weizhao Yang   +5 more
wiley   +1 more source

Loss‐of‐Function Variants in CCDC189 Cause Human Oligoasthenoteratozoospermia by Disrupting Sperm Flagellar and Acrosomal Architecture

Andrology, EarlyView.
ABSTRACT Background Oligoasthenoteratozoospermia (OAT), characterized by reduced sperm count, impaired motility, and abnormal morphology, is a major cause of male infertility with substantial genetic heterogeneity. However, the underlying genetic etiology remains unresolved in a large proportion of affected individuals.
Jianteng Zhou, Ghulam Mustafa, Tingting Lin, Jingwei Ye, Huan Zhang, Hanwei Jiang, Kexin Yang, Guoning Huang, Qinghua Shi   +8 more
wiley   +1 more source

Characterizing Runs of Homozygosity and Inbreeding in American Mink Using SNP Data and Pedigree Information

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT Inbreeding increases the likelihood of deleterious recessive alleles becoming homozygous and consequently affecting economically important traits. Runs of homozygosity (ROH), the continuous homozygous segments of the genome and the higher than expected homozygosity (HOM) are genomic indicators of inbreeding, quantified as FROH and FHOM ...
Persia Carol Thapa, Duy Ngoc Do, Pourya Davoudi, Ghader Manafiazar, Younes Miar   +4 more
wiley   +1 more source

Runs of Homozygosity and NetView analyses provide new insight into the genome-wide diversity and admixture of three German cattle breeds.

PLoS ONE, 2019
Angler (RVA) and Red-and-White dual-purpose (RDN) cattle were in the past decades crossed with influential Red Holstein (RH) sires. However, genome-wide diversity studies in these breeds are lacking.
Sowah Addo, Stefanie Klingel, Dirk Hinrichs, Georg Thaller   +3 more
doaj   +1 more source

Genome-wide detection of genetic structure and runs of homozygosity analysis in Anhui indigenous and Western commercial pig breeds using PorcineSNP80k data

BMC Genomics, 2022
Background Runs of homozygosity (ROH) are continuous homozygous regions typically located in the DNA sequence of diploid organisms. Identifications of ROH that lead to reduced performance can provide valuable insight into the genetic architecture of ...
Yao Jiang, Xiaojin Li, Jiali Liu, Wei Zhang, Mei Zhou, Jieru Wang, Linqing Liu, Shiguang Su, Fuping Zhao, Hongquan Chen, Chonglong Wang   +10 more
doaj   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger, Yuxi Zhou, Jiawen Yong, Lei Wang, Sabine Ruf, Joerg Meyle   +5 more
wiley   +1 more source