Results 21 to 30 of about 5,886 (212)

Associations of genome-wide and regional autozygosity with 96 complex traits in old order Amish

BMC Genomics, 2023
Background: Autozygosity, the proportion of the genome that is homozygous by descent, has been associated with variation in multiple health-related traits impacting evolutionary fitness. Autozygosity (FROH) is typically measured from runs of homozygosity
Megan T. Lynch, Kristin A. Maloney, Huichun Xu, James A. Perry, Regeneron Genetics Center, Alan R. Shuldiner, Braxton D. Mitchell   +6 more
doaj   +1 more source

Investigating inbreeding in the turkey (Meleagris gallopavo) genome

Poultry Science, 2021
: The detrimental effects of increased homozygosity due to inbreeding have prompted the development of methods to reduce inbreeding. The detection of runs of homozygosity (ROH), or contiguous stretches of homozygous marker genotypes, can be used to ...
Sarah M. Adams, Martijn F.L. Derks, Bayode O. Makanjuola, Gabriele Marras, Ben J. Wood, Christine F. Baes   +5 more
doaj   +1 more source

Comparative evaluation of genomic inbreeding parameters in seven commercial and autochthonous pig breeds

Animal, 2020
Single nucleotide polymorphism (SNP) genotyping tools, which can analyse thousands of SNPs covering the whole genome, have opened new opportunities to estimate the inbreeding level of animals directly using genome information.
G. Schiavo, S. Bovo, F. Bertolini, S. Tinarelli, S. Dall’Olio, L. Nanni Costa, M. Gallo, L. Fontanesi   +7 more
doaj   +1 more source

Discrete-time Model Reference Control of Milling Forces under Fractional Order Holds. Part I: Known Plant [PDF]

, 2006
This paper introduces a novel model-reference discrete-time control scheme applied to milling processes. The novelty of the scheme relies on the use of a fractional order hold (FROH) instead of a traditional ZOH used in the manufacturing literature to ...
De la Sen, Manuel, M. de la Sen, De la Sen Parte, Manuel, A. Ibeas, L. Rubio, Rubio, Luis, Rubio Rodriguez, Luis   +6 more
core   +1 more source

Assessment of runs of homozygosity islands and estimates of genomic inbreeding in Gyr (Bos indicus) dairy cattle

BMC Genomics, 2018
Background Runs of homozygosity (ROH) are continuous homozygous segments of the DNA sequence. They have been applied to quantify individual autozygosity and used as a potential inbreeding measure in livestock species. The aim of the present study was (i)
Elisa Peripolli, Nedenia Bonvino Stafuzza, Danísio Prado Munari, André Luís Ferreira Lima, Renato Irgang, Marco Antonio Machado, João Cláudio do Carmo Panetto, Ricardo Vieira Ventura, Fernando Baldi, Marcos Vinícius Gualberto Barbosa da Silva   +9 more
doaj   +1 more source

Water-rich C-type asteroids as early solar system carbonate factories [PDF]

, 2023
Micrometeorites represent a major potential source of volatiles for the early Earth, although often overlooked due to their small sizes and the effects of atmospheric entry.
Williams, Lynda B., Nava, Jacopo, Suttle, MD, Castillo-Rogez, Julie, Froh, Victoria, Castillo-Rogez, J, Nava, J, Bose, M, Williams, LB, Froh, V, Folco, Luigi, Suttle, Martin D., Folco, L, Bose, Maitrayee   +13 more
core   +1 more source

Runs of homozygosity analysis and genomic inbreeding estimation in Sumba Ongole cattle (Bos indicus) using a BovineSNP50K BeadChip [PDF]

Veterinary World
Background and Aim: Runs of homozygosity (ROH) is a biocomputational technique for identifying homozygous regions in the genomics of livestock. This study aimed to determine the ROH in Sumba Ongole (SO) bulls (n = 48) using the BovineSNP50K BeadChip ...
Widya Pintaka Bayu Putra, Hartati Hartati, Redi Aditama, Eko Handiwirawan, Endang Tri Margawati, Simon Elieser   +5 more
doaj   +1 more source

Genomic inbreeding measures applied to a population of mice divergently selected for birth weight environmental variance

Frontiers in Genetics, 2023
This study aimed to compare different inbreeding measures estimated from pedigree and molecular data from two divergent mouse lines selected for environmental birth weight during 26 generations.
Candela Ojeda-Marín, Isabel Cervantes, Nora Formoso-Rafferty, Juan Pablo Gutiérrez   +3 more
doaj   +1 more source

Autozygosity islands and ROH patterns in Nellore lineages: evidence of selection for functionally important traits

BMC Genomics, 2018
Background The aim of this study was to assess genome-wide autozygosity in a Nellore cattle population and to characterize ROH patterns and autozygosity islands that may have occurred due to selection within its lineages.
Elisa Peripolli, Julia Metzger, Marcos Vinícius Antunes de Lemos, Nedenia Bonvino Stafuzza, Sabrina Kluska, Bianca Ferreira Olivieri, Fabieli Louise Braga Feitosa, Mariana Piatto Berton, Fernando Brito Lopes, Danísio Prado Munari, Raysildo Barbosa Lôbo, Cláudio de Ulhoa Magnabosco, Fernando Di Croce, Jason Osterstock, Sue Denise, Angélica Simone Cravo Pereira, Fernando Baldi   +16 more
doaj   +1 more source

Assessing runs of homozygosity reveals production traits of Kazakh sheep breeds [PDF]

Brazilian Journal of Biology
Sheep breeding in Kazakhstan is one of the main local roles in animal husbandry. This article presents the results of a study of the genetic indicators of sheep breeds in Kazakhstan, in relation to their meat and wool productivity.
A. Khamzina, D. Smagulov, K. Dossybayev, J. Kantanen, K. Khamzin   +4 more
doaj   +1 more source