Results 111 to 120 of about 93,643 (333)

Frontotemporal dementia: diagnostic borders.

INFAD, 2018
Frontotemporal dementia (FTD) has a lower prevalence than Alzheimer Disease (AD), but its age of onset takes place earlier, between 50 and 60 years. For this reason, it supposes a great overload for caregivers and an increasing dependence for patients ...
Mª Cruz Pérez Lancho, Sergio García Bercianos   +1 more
doaj   +1 more source

Missense and silent tau gene mutations cause frontotemporal dementia with parkinsonism-chromosome 17 type, by affecting multiple alternative RNA splicing regulatory elements [PDF]

, 1999
Ian D’Souza, Parvoneh Poorkaj, Ming Hong, David Nochlin, Virginia M.‐Y. Lee, Thomas D. Bird, Gerard D. Schellenberg   +6 more
openalex   +1 more source

Low Frequency of Dementia with Lewy Bodies Diagnosis in a Colombian Memory Clinic

Movement Disorders Clinical Practice, EarlyView.
Abstract Background The global burden of dementia is increasing, particularly in low‐ and middle‐income countries. Dementia with Lewy bodies (DLB) is the second most common neurodegenerative dementia but remains underreported and frequently misdiagnosed. Its prevalence in Latin America is largely unknown.
Felipe Botero‐Rodríguez, José Manuel Santacruz‐Escudero, Miguel Germán Borda, Salomón Salazar‐Londoño, Carlos Cano‐Gutiérrez, Dag Aarsland, on behalf of COL‐DLB   +6 more
wiley   +1 more source

Research progress of behavioral variant frontotemporal dementia

Chinese Journal of Contemporary Neurology and Neurosurgery, 2015
There is no epidemiological data of frontotemporal dementia (FTD) in China. The application of updated diagnostic criteria, publishing of frontotemporal lobar degeneration (FTLD) consensus in China, development of multimodal imaging and biomarkers ...
Xiao-hua GU, Jun XU
doaj  

Substantia Nigra Iron Deposition in Lewy Body Disease: A Magnetic Resonance Imaging and Neuropathology Study

Movement Disorders, EarlyView.
Abstract Objective To compare iron deposition in the substantia nigra (SN) as measured with quantitative susceptibility mapping (QSM) on antemortem magnetic resonance imaging (MRI) between individuals with and without Lewy‐related pathology at autopsy. Methods We performed a retrospective cohort study including 54 participants who underwent autopsy and
Patricia Diaz‐Galvan, Scott A. Przybelski, Timothy G. Lesnick, Melissa E. Murray, Aivi Nguyen, Ross R. Reichard, Dennis W. Dickson, Daisuke Ono, Matthew L. Senjem, Christopher G. Schwarz, Jeffrey Gunter, Val Lowe, Leah K. Forsberg, Julie A. Fields, Rodolfo Savica, Jonathan Graff‐Radford, Vijay K. Ramanan, David Jones, Hugo Botha, Erik K. St. Louis, David Knopman, Gregory S. Day, Neill Graff‐Radford, Walter Kremers, Ronald C. Petersen, Clifford R. Jack Jr, Tanis J. Ferman, Bradley F. Boeve, Kejal Kantarci   +28 more
wiley   +1 more source

The temporal variant of frontotemporal dementia [PDF]

, 1997
Terri Edwards-Lee, Bruce L. Miller, D. Frank Benson, Jeffrey L. Cummings, Glenda Russell, Keith W. Boone, Ismaël Mena   +6 more
openalex   +1 more source

Generation and characterization of two induced pluripotent stem cell lines (ICGi052-A and ICGi052-B) from a patient with frontotemporal dementia with parkinsonism-17 associated with the pathological variant c.2013T>G in the MAPT gene

Вавиловский журнал генетики и селекции
Frontotemporal dementia with parkinsonism-17 is a neurodegenerative disease characterised by pathological aggregation of the tau protein with the formation of neurofibrillary tangles and subsequent neuronal death.
E. V. Grigor’eva, A. A. Malakhova, E. S. Yarkova, J. M. Minina, Y. V. Vyatkin, J. A. Nadtochy, E. A. Khabarova, J. A. Rzaev, S. P. Medvedev, S. M. Zakian   +9 more
doaj   +1 more source

Impaired Glymphatic Clearance, Measured Using Diffusion Tensor Image Analysis Along the Perivascular Space (DTI‐ALPS), is Linked to Poor Cognitive Outcomes in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Impaired glymphatic clearance may contribute to pathological accumulations in Parkinson's (PD), but how it interacts with other processes causing dementia remains unclear. Diffusion tensor image analysis along the perivascular space (DTI‐ALPS) has been proposed as an indirect proxy for glymphatic clearance. Objectives To clarify DTI‐
Angeliki Zarkali, George Thomas, Ross Paterson, Naomi Hannaway, Ivelina Dobreva, Amanda J. Heslegrave, Elena Veleva, Henrik Zetterberg, Rimona S. Weil   +8 more
wiley   +1 more source

Amyotrophic lateral sclerosis in a combination with frontotemporal dementia: A clinical case study

Heart Vessels and Transplantation
Objective: Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease affecting both central and peripheral motor neurons, presenting a significant challenge in modern neurology. This article discusses the multifactorial nature of ALS,
Nurzhan T. Dzhaparalieva, Eldana .B.Bolotbekova, Begimai B. Kadyrova, Irina A. Sverdlova, Asel T. Jusupova   +4 more
doaj   +1 more source

A Novel α‐Synuclein K58N Missense Variant in a Patient with Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Parkinson's disease (PD) is a complex multifactorial disorder with a genetic component in about 15% of cases. Multiplications and point mutations in SNCA gene, encoding α‐synuclein (aSyn), are linked to rare familial forms of PD. Objective Our goal was to assess the clinical presentation and the biological effects of a novel K58N ...
Mohammed Al‐Azzani, Sandrina Weber, Nagendran Ramalingam, Maria Ramón, Liana Shvachiy, Gonçalo Mestre, Michael Zech, Kevin Sicking, Alain Ibáñez de Opakua, Vidyashree Jayanthi, Leslie Amaral, Aishwarya Agarwal, Aswathy Chandran, Susana R. Chaves, Juliane Winkelmann, Claudia Trenkwalder, Maike Schwager, Silke Pauli, Ulf Dettmer, Claudio O. Fernández, Janin Lautenschläger, Markus Zweckstetter, Ruben Fernandez Busnadiego, Brit Mollenhauer, Tiago Fleming Outeiro   +24 more
wiley   +1 more source