Results 131 to 140 of about 53,213 (267)

Increased granulovacuolar degeneration in the thalamus and higher neurofibrillary tangle Braak stages in bipolar disorder

open access: yesPsychiatry and Clinical Neurosciences, EarlyView.
Aim Recent neuropathological studies suggest that the accumulation of neurodegenerative disease–associated proteins in subcortical structures may contribute to mood symptoms. Animal models have highlighted the role of the paraventricular thalamic nucleus (PVT) in bipolar disorder (BD) pathophysiology.
Akito Nagakura   +6 more
wiley   +1 more source

Changes in the cortical GABAergic inhibitory system with ageing and ageing‐related neurodegenerative diseases

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend With ageing and age‐related neurodegenerative diseases, the amount of GABA and GABAergic inhibition as well as the modulation (indicated by sine wave) of GABAergic inhibition is reduced, whereas excitation is increased. In many parts of the brain, this leads to a mismatch of facilitatory (green neurons) and inhibitory (red ...
Wolfgang Taube, Benedikt Lauber
wiley   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney   +4 more
wiley   +1 more source

Large language models for bioinformatics

open access: yesQuantitative Biology, Volume 14, Issue 1, March 2026.
Abstract With the rapid advancements in large language model technology and the emergence of bioinformatics‐specific language models (BioLMs), there is a growing need for a comprehensive analysis of the current landscape, computational characteristics, and diverse applications.
Wei Ruan   +54 more
wiley   +1 more source

Medicaid expansion and diagnosis experiences of people with frontotemporal dementia

open access: yesAlzheimer's &Dementia: Behavior &Socioeconomics of Aging, Volume 1, Issue 4, December 2025.
Abstract INTRODUCTION Timely and accurate diagnosis of frontotemporal dementia (FTD) is essential for improving patient quality of life and alleviating caregiver burden. However, individuals with FTD often face barriers to care due to limited insurance coverage.
Catherine E. A. Scipion   +3 more
wiley   +1 more source

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