Results 131 to 140 of about 98,352 (316)

p97 Disease Mutations Modulate Nucleotide-Induced Conformation to Alter Protein-Protein Interactions. [PDF]

open access: yes, 2016
The AAA+ ATPase p97/VCP adopts at least three conformations that depend on the binding of ADP and ATP and alter the orientation of the N-terminal protein-protein interaction (PPI) domain into up and down conformations.
Arkin, Michelle   +2 more
core  

STELLA-FTD: Examination of a Behavior Change Intervention for Frontotemporal Dementia Family Care Partners. [PDF]

open access: yesAlzheimers Dement Behav Socioecon Aging
Abstract INTRODUCTION Frontotemporal dementia (FTD) is the most common dementia in people under age 60. Although FTD is often characterized by behavioral symptoms, few national interventions address management of these symptoms. Here we describe our protocol for Support via Technology: Living and Learning with Advancing FTD (STELLA‐FTD), an ...
Lindauer A   +7 more
europepmc   +2 more sources

State and trait characteristics of anterior insula time-varying functional connectivity. [PDF]

open access: yes, 2020
The human anterior insula (aINS) is a topographically organized brain region, in which ventral portions contribute to socio-emotional function through limbic and autonomic connections, whereas the dorsal aINS contributes to cognitive processes through ...
Allen, Isabel   +18 more
core  

Frontotemporal dementia and parkinsonism linked to chromosome 17: A consensus conference [PDF]

open access: bronze, 1997
Norman L. Foster   +6 more
openalex   +1 more source

Frontotemporal dementia: Clinical aspects, genetics, and neuropathology of a family with a C9ORF72 expansion in Argentina

open access: yesBrain Pathology, EarlyView.
Immunohistochemistry for TDP‐43: (A)—Dentate gyrus; (B)—Temporal lobe. Abstract Frontotemporal dementia (FTD) is the second most common cause of early‐onset dementia, typically manifesting before the age of 65, with a mean onset at 58 years. FTD may encompass a spectrum of neurodegenerative disorders resulting from frontotemporal lobar degeneration ...
Karen Daniela Román   +13 more
wiley   +1 more source

Examining the relation between bilingualism and age of symptom onset in frontotemporal dementia [PDF]

open access: hybrid, 2023
Jessica de Leon   +9 more
openalex   +1 more source

Implant Therapy in Patients With Neurodegenerative Diseases—A Scoping Review

open access: yesClinical Oral Implants Research, EarlyView.
ABSTRACT Objectives The increasing longevity of populations has resulted in a growing number of older adults requiring prosthodontic care, including those with neurodegenerative diseases (NDs). Neurodegenerative diseases pose significant challenges to prosthodontic care, and it remains unclear whether implant therapy in this population achieves ...
Lysandre David   +5 more
wiley   +1 more source

Social cognition in amyotrophic lateral sclerosis [PDF]

open access: yes, 2011
Andersen   +6 more
core   +1 more source

Frontotemporal dementia [PDF]

open access: yesContinuum, 2007
Indre Viskontas, Bruce Miller
openaire   +1 more source

Disentangling the relationship between glucose, insulin and brain health: A UK Biobank study

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Background Glycaemic traits are associated with poorer brain health and dementia risk. Recent advances in genetic instruments for specific glycaemic markers enable an in‐depth investigation of the likely nature of associations and underlying mechanisms between diabetes‐related mechanisms and brain health and dementia.
Andrew C. Mason   +7 more
wiley   +1 more source

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