Results 131 to 140 of about 98,352 (316)
p97 Disease Mutations Modulate Nucleotide-Induced Conformation to Alter Protein-Protein Interactions. [PDF]
The AAA+ ATPase p97/VCP adopts at least three conformations that depend on the binding of ADP and ATP and alter the orientation of the N-terminal protein-protein interaction (PPI) domain into up and down conformations.
Arkin, Michelle +2 more
core
STELLA-FTD: Examination of a Behavior Change Intervention for Frontotemporal Dementia Family Care Partners. [PDF]
Abstract INTRODUCTION Frontotemporal dementia (FTD) is the most common dementia in people under age 60. Although FTD is often characterized by behavioral symptoms, few national interventions address management of these symptoms. Here we describe our protocol for Support via Technology: Living and Learning with Advancing FTD (STELLA‐FTD), an ...
Lindauer A +7 more
europepmc +2 more sources
State and trait characteristics of anterior insula time-varying functional connectivity. [PDF]
The human anterior insula (aINS) is a topographically organized brain region, in which ventral portions contribute to socio-emotional function through limbic and autonomic connections, whereas the dorsal aINS contributes to cognitive processes through ...
Allen, Isabel +18 more
core
Frontotemporal dementia and parkinsonism linked to chromosome 17: A consensus conference [PDF]
Norman L. Foster +6 more
openalex +1 more source
Immunohistochemistry for TDP‐43: (A)—Dentate gyrus; (B)—Temporal lobe. Abstract Frontotemporal dementia (FTD) is the second most common cause of early‐onset dementia, typically manifesting before the age of 65, with a mean onset at 58 years. FTD may encompass a spectrum of neurodegenerative disorders resulting from frontotemporal lobar degeneration ...
Karen Daniela Román +13 more
wiley +1 more source
Examining the relation between bilingualism and age of symptom onset in frontotemporal dementia [PDF]
Jessica de Leon +9 more
openalex +1 more source
Implant Therapy in Patients With Neurodegenerative Diseases—A Scoping Review
ABSTRACT Objectives The increasing longevity of populations has resulted in a growing number of older adults requiring prosthodontic care, including those with neurodegenerative diseases (NDs). Neurodegenerative diseases pose significant challenges to prosthodontic care, and it remains unclear whether implant therapy in this population achieves ...
Lysandre David +5 more
wiley +1 more source
Disentangling the relationship between glucose, insulin and brain health: A UK Biobank study
Abstract Background Glycaemic traits are associated with poorer brain health and dementia risk. Recent advances in genetic instruments for specific glycaemic markers enable an in‐depth investigation of the likely nature of associations and underlying mechanisms between diabetes‐related mechanisms and brain health and dementia.
Andrew C. Mason +7 more
wiley +1 more source

