Results 141 to 150 of about 53,213 (267)

Examining neuropsychiatric symptoms and functional decline in behavioral variant frontotemporal dementia. [PDF]

Int Rev Psychiatry
Morrow CB, Sah E, Onyike CU.
europepmc   +1 more source

Higher neighborhood deprivation is associated with accelerated disease progression in behavioral‐variant frontotemporal degeneration

Alzheimer's &Dementia: Behavior &Socioeconomics of Aging, Volume 1, Issue 4, December 2025.
Abstract INTRODUCTION Neighborhood deprivation is associated with shorter survival, cognitive impairment, and neurodegeneration in aging and Alzheimer's disease. However, the association of neighborhood deprivation with disease progression in behavioral‐variant frontotemporal degeneration (bvFTD) is unknown.
Rory Boyle, Nadia Dehghani, Sheina Emrani, Anil R. Wadhwani, Melanie Matyi, Katheryn A. Q. Cousins, Emma Rhodes, Brian Nelson, Shana D. Stites, Sharon X. Xie, Laynie Dratch, Vivianna M. Van Deerlin, Allison Snyder, David J. Irwin, Corey T. McMillan, Lauren Massimo   +15 more
wiley   +1 more source

Financial strain and depressive symptoms among parent‐child dyads coping with dementia, depression, or delirium

Alzheimer's &Dementia: Behavior &Socioeconomics of Aging, Volume 1, Issue 4, December 2025.
Abstract INTRODUCTION Two studies examined associations between financial strain and depressive symptoms among dyads of parents living with dementia, depression, or recent delirium and one adult child. METHODS Study 1 included 147 parent–child dyads in which the parent had early‐stage cognitive impairment. Study 2 included 115 parent–child dyads coping
Joan K. Monin, Holly Laws, Katie Newkirk, Kalisha Bonds Johnson, Richard H. Fortinsky   +4 more
wiley   +1 more source

Progranulin mutations and amyotrophic lateral sclerosis or amyotrophic lateral sclerosis-frontotemporal dementia phenotypes [PDF]

, 2006
Jennifer C. Schymick, Yi Yang, Peter M. Andersen, Jean Paul Vonsattel, M. J. Greenway, Parastoo Momeni, Joshua W. Elder, Adriano Chió, Gabriella Restagno, Wim Robberecht, Caroline Dahlberg, Odity Mukherjee, Alison Goate, Neill R. Graff‐Radford, Richard J. Caselli, M. Hutton, Jenny Gass, Ashley Cannon, Rosa Rademakers, Andrew Singleton, Orla Hardiman, Jeffrey D. Rothstein, John Hardy, Bryan J. Traynor   +23 more
openalex   +1 more source

She asked if she had dementia: Caregivers’ insights on lucidity in late stages of dementia and its impact

Alzheimer's &Dementia: Behavior &Socioeconomics of Aging, Volume 1, Issue 4, December 2025.
Abstract BACKGROUND Some persons with late‐stage Alzheimer's disease and related dementias (ADRD) and seemingly very minimal cognitive abilities have transient episodes of unexpected, spontaneous, meaningful, and relevant communication or behavior. This phenomenon, referred to as lucidity, is not well understood, although it is frequently observed by ...
Quinton D. Cotton, Robyn Birkeland, Dionne Bailey, Sesen Gidey, Kyungmin Kim, Maria I. Lapid, Lauren R. Bangerter, Yin Liu, Dawn M. Finnie, Joseph E. Gaugler, Joan M. Griffin   +10 more
wiley   +1 more source

Microstructural grey matter alterations in patients with behavioural variant frontotemporal dementia. [PDF]

Brain Commun
Akbarian B, Hett K, Phan T, Lee JJ, Eaton J, Donahue MJ, Darby RR.   +6 more
europepmc   +1 more source

PRMT1 in Health and Disease: Emerging Perspectives From Molecular Mechanisms to Therapeutic Strategies

MedComm, Volume 6, Issue 12, December 2025.
Protein arginine methyltransferase 1 (PRMT1) is a pivotal enzyme that catalyzes the asymmetric dimethylation of arginine residues, thereby functioning as a critical epigenetic regulator of diverse biological processes such as gene expression, RNA splicing, and DNA repair.
Yanqun Luo, Ying Gao, Xiaoliang Deng, Lei Wang, Tao Wu   +4 more
wiley   +1 more source

Association between higher cerebrospinal fluid levels of phosphorylated tau and reduced depressive symptoms in patients with cognitive decline

Psychiatry and Clinical Neurosciences Reports, Volume 4, Issue 4, December 2025.
Abstract Aim In individuals with cognitive decline, depressive symptoms can affect disease progression and quality of life. One factor that may be associated with depressive symptoms is phosphorylated tau (p‐tau). However, the association between p‐tau and depressive symptoms remains controversial.
Takashi Ozaki, Naoki Hashimoto, Hisashi Narita, Niki Udo, Shizuka Mito, Shin Nakagawa, Ichiro Kusumi, Takahiro A. Kato   +7 more
wiley   +1 more source

Executive function and the feasibility of clinical trials for frontotemporal dementia. [PDF]

Lancet Reg Health Eur
Coleman KKL, Finger E.
europepmc   +1 more source

Integrative proteomic analysis provides novel therapeutic insights for etiological subtypes of diabetes

Diabetes, Obesity and Metabolism, Volume 27, Issue 12, Page 6894-6904, December 2025.
Abstract Aims Type 2 diabetes (T2D) is a highly heterogeneous disease characterised by subtypes with variations in aetiology, disease progression, and risk of complications. However, potential drug targets for these subtypes have not been explored. This study aims to investigate potential drug targets by integrating proteomics.
Jiahe Wei, Hanzhang Wu, Ningjian Wang, Jiahao Zhu, Ranjit Mohan Anjana, Aleksandr V. Sokolov, Helgi B. Schiöth, Viswanathan Mohan, Xiao Tan   +8 more
wiley   +1 more source