Progranulin mutations and amyotrophic lateral sclerosis or amyotrophic lateral sclerosis-frontotemporal dementia phenotypes [PDF]
, 2006 Jennifer C. Schymick +23 more
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Frontotemporal dementia mutant tau (P301L) locks Fyn in an open, active conformation conducive to nanoclustering [PDF]
, 2020 Christopher Small +5 more
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Artificial Intelligence Methods Based Hierarchical Classification of Frontotemporal Dementia to Improve Diagnostic Predictability [PDF]
, 2021 Km Poonam +2 more
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Category fluency and creative potential in semantic aphasia
Journal of Neuropsychology, EarlyView.Abstract Creative cognition involves linking weakly or unrelated concepts, enabled by semantic control (inhibiting dominant associations to retrieve weaker ones) or through spreading activation within the semantic system. Semantic aphasia (SA) patients have impaired semantic control despite relatively preserved semantic representations.
Hannah E. Thompson +4 more
wiley +1 more source
Prosocial deficits in behavioral variant frontotemporal dementia relate to reward network atrophy [PDF]
, 2017 Virginia E. Sturm +9 more
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Talking therapies for anxiety and depression in people affected by dementia: A scoping meta‐review
Psychology and Psychotherapy: Theory, Research and Practice, EarlyView.Abstract Background Symptoms of anxiety and depression are common in people affected by dementia (people with dementia and family carers). There are many reviews of psychological interventions to reduce stress and distress in people with dementia and family carers, but little cross‐fertilisation with the evidence base underpinning NHS Talking Therapies
Georgina Charlesworth +2 more
wiley +1 more source
, 2021 Frontotemporal dementia (FTD) is a neurodegenerative disorder of insidious onset, and the term encompasses several entities. It is mostly sporadic. Epidemiologically, its prevalence as a dementia is third behind Alzheimer's disease and dementia with Lewy bodies (Bang et al., 2018).
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The Journal of Physiology, EarlyView.Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney +4 more
wiley +1 more source
Familial Frontotemporal Dementia-Associated Presenilin-1 c.548G>T Mutation Causes Decreased mRNA Expression and Reduced Presenilin Function in Knock-In Mice [PDF]
, 2012 Hirotaka Watanabe +4 more
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