Results 91 to 100 of about 21,388 (227)
Associations between TMEM106B C‐terminal fragment aggregation, age, and TDP‐43 or tau pathology
Brain Pathology, EarlyView.TMEM106B C‐terminal fragment (CTF) aggregation represents an age‐associated, common, diffuse phenomenon emerging after midlife with a weak association with TDP‐43 or tau pathology. These findings suggest that TMEM106B fibrillization may define a distinct axis of protein aggregation in the aging human brain. Abstract Transmembrane protein 106B (TMEM106B)
Albert Acewicz +5 more
wiley +1 more source
Neuropsychological Evaluation of the Frontotemporal Dementia
, 2016 Diagnosis of Frontotemporal dementia (FTD) requires -besides brain imagining- a careful evaluation of diverse aspects including genetic and neuropathological, behavioural problems and cognitive processes.
Martínez Cuitiño Carricaburo, María Macarena +2 more
core +1 more source
, 2021 Frontotemporal dementia (FTD) is a neurodegenerative disorder of insidious onset, and the term encompasses several entities. It is mostly sporadic. Epidemiologically, its prevalence as a dementia is third behind Alzheimer's disease and dementia with ...
Miruzzi, Mark
core
Epidemiological Survey of Frontotemporal Lobar Degeneration in Tottori Prefecture, Japan
Dementia and Geriatric Cognitive Disorders Extra, 2012 Background: The prevalence of frontotemporal lobar degeneration (FTLD) in Japan is unknown. An epidemiological survey study of FTLD was undertaken in Tottori Prefecture, a district in the western region of Japan.
Kenji Wada-Isoe +10 more
doaj +1 more source
Proteostasis of organelles in aging and disease
The FEBS Journal, EarlyView.Cells rely on regulated proteostasis mechanisms to keep their internal compartments functioning properly. When these mechanisms fail, damaged proteins accumulate, disrupting organelles, such as the nucleus, mitochondria, endoplasmic reticulum, Golgi, and lysosomes, as well as membraneless organelles, such as stress granules, processing bodies, the ...
Yara Nabawi +5 more
wiley +1 more source
Early onset frontotermporal dementia and alzheimers disease: diagnosis, treatment and care
, 2007 This research investigated two groups of patients diagnosed with dementia before the age of sixty-five. The patients were diagnosed with Alzheimer's Disease (AD, n = 25) and Frontotemporal Dementia (FTD, n = 37).
Rudge, John
core
Journal of Advanced Nursing, EarlyView.ABSTRACT Aim To explore how family resilience emerges and unfolds in dementia. Design Qualitative meta‐synthesis using thematic synthesis. Data Sources PubMed, CINAHL, Web of Science, PsycINFO were searched from inception through August 26, 2025. Methods Studies examining family‐level resilience, adaptation or coping in home‐based dementia care using ...
Yoosun Yang, Jun‐Ah Song
wiley +1 more source
, 2022 “Frontotemporal dementia” (FTD) is a clinical syndrome characterized by the focal involvement of the frontal and/or temporal lobes. FTD has three clinical phenotypes: the behavioral variant and two linguistic subtypes, namely, non-fluent/agrammatic ...
Caramelli, Paulo +17 more
core +1 more source
Journal of Neuropsychology, EarlyView.Abstract We aimed at validating the Mini Social Cognition and Emotional Assessment (Mini‐SEA) in a German cohort of mildly impaired behavioural‐variant frontotemporal dementia (bvFTD) patients and healthy controls. The Mini‐SEA comprises the Facial Emotion Recognition Test (FERT) and the Faux Pas Test (FPT) measuring Theory of Mind (ToM) abilities in ...
Cem Doğdu +27 more
wiley +1 more source
Major Depression and Onset of Frontotemporal Dementia
Neuropsychiatric Disease and Treatment, 2022 Małgorzata Urban-Kowalczyk,1 Magdalena Kasjaniuk,2 Janusz Śmigielski,3 Magdalena Kotlicka-Antczak1 1Department of Affective and Psychotic Disorders, Medical University of Lodz, Lodz, Poland; 2Central Teaching Hospital of the Medical ...
Urban-Kowalczyk M +3 more
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