Results 51 to 60 of about 672,406 (301)

A Bio-Wicking System to Prevent Frost Heave in Alaskan Pavements: Phase II Implementation [PDF]

open access: yes, 2019
Water within pavement layers is the major cause of pavement deterioration. High water content results in significant reduction in soil’s resilient behavior and an increase in permanent deformation.
Galinmoghadan, Javad   +2 more
core  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

A Retrospective Analysis of Itch Intensity and Comorbidities in Lichen Simplex Chronicus

open access: yesActa Dermato-Venereologica
Lichen simplex chronicus is a chronic pruritic skin condition that significantly impacts quality of life. This retrospective study analysed 125 patients with clinically confirmed lichen simplex chronicus seen at a tertiary academic centre to characterize
Kayla D. Mashoudy   +4 more
doaj   +1 more source

Insulating structure Patent [PDF]

open access: yes, 1961
Insulating system for receptacles of liquefied gases using wire cloth for forming frost ...
Burrows, D. L.
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Count me in! Gender and ethnic minority attainment in school science [PDF]

open access: yes, 2005
There is no single 'solution' to the 'problem' of under-achievement in school science by certain groups. Such under-achievement is strongly connected to the ways that society views the members of these groups.
Frost, Jennifer   +3 more
core   +1 more source

The urban heat island effect on frost damage of natural building stones [PDF]

open access: yes, 2019
Climate plays a major role in the weathering of building stones. This study specifically investigates the influence of the urban heat island (UHI)in Ghent, Belgium,on freeze-thaw (F-T) weathering ofnatural building stonesand their ...
Calle, Klaas   +5 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

The control of carbon dioxide cryodeposits [PDF]

open access: yes
An experimental study has been conducted to investigate the parameters affecting the cryodeposition of carbon dioxide frost. In the investigation carbon dioxide frost was cryodeposited from a helium-carbon dioxide mixture into a layer of fibrous ...
Sharpe, E. L.
core   +1 more source

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