Biotechnology for Biofuels and Bioproducts, 2023 Background The efficient production of sustainable biofuels is important for the reduction of greenhouse gas emissions. Clostridium thermocellum ATCC 27405 is a candidate for ethanol production from lignocellulosic biomass using consolidated ...
Steve R. Daley +2 more
doaj +1 more source
Adaptive evolution of the Streptococcus pyogenes regulatory aldolase LacD.1 [PDF]
, 2013 In the human-pathogenic bacterium Streptococcus pyogenes, the tagatose bisphosphate aldolase LacD.1 likely originated through a gene duplication event and was adapted to a role as a metabolic sensor for regulation of virulence gene transcription ...
Caparon, Michael, Cusumano, Zachary
core +2 more sources
Inhibitors of Class II fructose 1,6‐bisphosphate aldolase
The FASEB Journal, 2006 Fructose 1,6‐bisphosphate (FBP) aldolase (E.C. 4.1.2.13 ) catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3‐phosphate in the Calvin cycle, glycolysis and gluconeogenesis.
Geneviève Labbé +5 more
openaire +1 more source
Isomer activation controls stereospecificity of class I fructose-1,6-bisphosphate aldolases [PDF]
Journal of Biological Chemistry, 2017 Fructose-1,6-bisphosphate (FBP) aldolase, a glycolytic enzyme, catalyzes the reversible and stereospecific aldol addition of dihydroxyacetone phosphate (DHAP) and d-glyceraldehyde 3-phosphate (d-G3P) by an unresolved mechanism. To afford insight into the molecular determinants of FBP aldolase stereospecificity during aldol addition, a key ternary ...
Paul W. Heron, Jurgen Sygusch
openaire +2 more sources
Scientific Reports, 2017 Sugar 4-epimerization reactions are important for the production of rare sugars and their derivatives, which have various potential industrial applications.
Seon-Hwa Lee +6 more
doaj +1 more source
A deeply branching thermophilic bacterium with an ancient acetyl-CoA pathway dominates a subsurface ecosystem. [PDF]
PLoS ONE, 2012 A nearly complete genome sequence of Candidatus 'Acetothermum autotrophicum', a presently uncultivated bacterium in candidate division OP1, was revealed by metagenomic analysis of a subsurface thermophilic microbial mat community.
Hideto Takami +11 more
doaj +1 more source
Identification of Early Salt-Stress-Responsive Proteins in In Vitro Prunus Cultured Excised Roots
Plants, 2022 Fruit-tree rootstock selection is a challenge under a scenario of growing environmental stresses in which the soil and climate are greatly affected. Salinization is an increasing global process that severely affects soil fertility.
Emma Sevilla +5 more
doaj +1 more source
Genetic engineering of the Calvin cycle toward enhanced photosynthetic CO2 fixation in microalgae
Biotechnology for Biofuels, 2017 Background Photosynthetic microalgae are emerging as potential biomass feedstock for sustainable production of biofuels and value-added bioproducts. CO2 biomitigation through these organisms is considered as an eco-friendly and promising alternative to ...
Bo Yang +7 more
doaj +1 more source
Deletion of transketolase triggers a stringent metabolic response in promastigotes and loss of virulence in amastigotes of Leishmania mexicana [PDF]
, 2018 Transketolase (TKT) is part of the non-oxidative branch of the pentose phosphate pathway (PPP). Here we describe the impact of removing this enzyme from the pathogenic protozoan Leishmania mexicana.
A Chokkathukalam +78 more
core +10 more sources
Straightforward chemo-enzymatic synthesis of new aminocyclitols, analogues of valiolamine and their evaluation as glycosidase inhibitors. [PDF]
, 2006 An efficient fructose-1,6-bisphosphate aldolase mediated synthesis of new aminocyclitol analogues of valiolamine is described. The one-pot process where four stereocentres are created involves the formation of two carbon–carbon bonds. One is catalysed by
Ahbala, Mustapha +3 more
core +3 more sources