Results 1 to 10 of about 21,838 (240)

Fructose-Bisphosphate Aldolase Mediating Pollen-Food Allergy Syndrome [PDF]

Journal of Asthma and Allergy
Lisha Li,* Junda Li,* Kai Guan Department of Allergy, Beijing Key Laboratory of Precision Medicine for Diagnosis and Treatment on Allergic Diseases, National Clinical Research Center for Dermatologic and Immunologic Diseases, Peking Union Medical
Li L, Li J, Guan K
doaj   +6 more sources

Epitope-Based Peptide Vaccine Against Fructose-Bisphosphate Aldolase of Using Immunoinformatics Approaches [PDF]

Bioinformatics and Biology Insights, 2018
Background: Mycetoma is a distinct body tissue destructive and neglected tropical disease. It is endemic in many tropical and subtropical countries.
Arwa A Mohammed, Ayman MH ALnaby, Solima M Sabeel, Fagr M AbdElmarouf, Amina I Dirar, Mostafa M Ali, Mustafa A Khandgawi, Abdelhameed M Yousif, Eman M Abdulgadir, Magdi A Sabahalkhair, Ayman E Abbas, Mohammed A Hassan   +11 more
doaj   +5 more sources

Design of Epitope-Based Peptide Vaccine against Pseudomonas aeruginosa Fructose Bisphosphate Aldolase Protein Using Immunoinformatics [PDF]

Journal of Immunology Research, 2020
Pseudomonas aeruginosa is a common pathogen that is responsible for serious hospital-acquired infections, ventilator-associated pneumonia, and various sepsis syndromes.
Mustafa Elhag, Ruaa Mohamed Alaagib, Nagla Mohamed Ahmed, Mustafa Abubaker, Esraa Musa Haroun, Sahar Obi Abd Albagi, Mohammed A. Hassan   +6 more
doaj   +6 more sources

Characterization of Fructose-1,6-Bisphosphate Aldolase 1 of Echinococcus multilocularis [PDF]

Veterinary Sciences, 2021
Glycolysis is one of the important ways by which Echinococcus multilocularis acquires energy. Fructose-1, 6-bisphosphate aldolase (FBA) plays an important role in this process, but it is not fully characterized in E. multilocularis yet.
Xuedong He, Jing Zhang, Yue Sun, Tianyan Lan, Xiaola Guo, Xiaoqiang Wang, Omnia M. Kandil, Mazhar Ayaz, Xuenong Luo, Houhui Song, Yadong Zheng   +10 more
doaj   +2 more sources

Multifunctional Fructose 1,6-Bisphosphate Aldolase as a Therapeutic Target [PDF]

Frontiers in Molecular Biosciences, 2021
Fructose 1,6-bisphosphate aldolase is a ubiquitous cytosolic enzyme that catalyzes the fourth step of glycolysis. Aldolases are classified into three groups: Class-I, Class-IA, and Class-II; all classes share similar structural features but low amino ...
David B. Pirovich, Akram A. Da’dara, Patrick J. Skelly   +2 more
doaj   +2 more sources

Epitope-Based Peptide Vaccine Design against Fructose Bisphosphate Aldolase of Candida glabrata: An Immunoinformatics Approach [PDF]

Journal of Immunology Research, 2021
Background. Candida glabrata is a human opportunistic pathogen that can cause life-threatening systemic infections. Although there are multiple effective vaccines against fungal infections and some of these vaccines are engaged in different stages of ...
Lina Mohamed Elamin Elhasan, Mohamed B. Hassan, Reham M. Elhassan, Fatima A. Abdelrhman, Essam A. Salih, Asma Ibrahim H, Amna A. Mohamed, Hozaifa S. Osman, Marwa Saad M. Khalil, Athar A. Alsafi, Abeer Babiker Idris, Mohamed A. Hassan   +11 more
doaj   +2 more sources

The fructose-bisphosphate, Aldolase A (ALDOA), facilitates DNA-PKcs and ATM kinase activity to regulate DNA double-strand break repair [PDF]

Scientific Reports, 2023
Glucose metabolism and DNA repair are fundamental cellular processes frequently dysregulated in cancer. In this study, we define a direct role for the glycolytic Aldolase A (ALDOA) protein in DNA double-strand break (DSB) repair.
Thais Sobanski, Amila Suraweera, Joshua T. Burgess, Iain Richard, Chee Man Cheong, Keyur Dave, Maddison Rose, Mark N. Adams, Kenneth J. O’Byrne, Derek J. Richard, Emma Bolderson   +10 more
doaj   +2 more sources

Interrogating the Role of the Two Distinct Fructose-Bisphosphate Aldolases of Bacillus methanolicus by Site-Directed Mutagenesis of Key Amino Acids and Gene Repression by CRISPR Interference [PDF]

Frontiers in Microbiology, 2021
The Gram-positive Bacillus methanolicus shows plasmid-dependent methylotrophy. This facultative ribulose monophosphate (RuMP) cycle methylotroph possesses two fructose bisphosphate aldolases (FBA) with distinct kinetic properties.
Kerstin Schultenkämper, Desirée D. Gütle, Marina Gil López, Laura B. Keller, Lin Zhang, Oliver Einsle, Jean-Pierre Jacquot, Volker F. Wendisch   +7 more
doaj   +2 more sources

A deeply branching thermophilic bacterium with an ancient acetyl-CoA pathway dominates a subsurface ecosystem. [PDF]

PLoS ONE, 2012
A nearly complete genome sequence of Candidatus 'Acetothermum autotrophicum', a presently uncultivated bacterium in candidate division OP1, was revealed by metagenomic analysis of a subsurface thermophilic microbial mat community.
Hideto Takami, Hideki Noguchi, Yoshihiro Takaki, Ikuo Uchiyama, Atsushi Toyoda, Shinro Nishi, Gab-Joo Chee, Wataru Arai, Takuro Nunoura, Takehiko Itoh, Masahira Hattori, Ken Takai   +11 more
doaj   +14 more sources

The metabolic enzyme fructose-1,6-bisphosphate aldolase acts as a transcriptional regulator in pathogenic Francisella

Nature Communications, 2017
The enzyme fructose-bisphosphate aldolase (FBA) plays central roles in glycolysis and gluconeogenesis. Here, Ziveri et al. show that FBA of the pathogen Francisella novicida acts, in addition, as a transcriptional regulator and is important for bacterial
Fabiola Tros, Ida Chiara Guerrera, Monique Barel   +2 more
exaly   +2 more sources