Fructose is a simple sugar found in many foods. Common table sugar is made of equal amounts fructose and glucose. Similarly, high-fructose corn syrup, commonly used to sweeten foods, contains a mixture of fructose and glucose.
Wendy J. Dahl+2 more
doaj +5 more sources
A role for the increased intake of dietary fructose in general and high-fructose corn syrup (HFCS) in particular in the current obesity epidemic has been proposed. Consumed fructose and glucose have different rates of gastric emptying, are differentially absorbed from the gastrointestinal tract, result in different endocrine profiles, and have ...
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Metabolite-mediated catalyst conversion of PFK and PFP [PDF]
Metabolites known to occur in the cytosol of photosynthetic leaf cells were found to mediate the reversible conversion of pyrophosphate—D-fructose-6-phosphate 1-phosphotransferase (PFP) to phosphofructokinase (PFK) in partially purified preparations from
Balogh, Arpad+5 more
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Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK
The major energy source for most cells is glucose, from which ATP is generated via glycolysis and/or oxidative metabolism. Glucose deprivation activates AMP-activated protein kinase (AMPK), but it is unclear whether this activation occurs solely via ...
Chensong Zhang+18 more
semanticscholar +1 more source
Fructose in obesity and cognitive decline: is it the fructose or the excess energy? [PDF]
We read with interest the review by Lakhan and Kirchgessner, proposing that high fructose intake promotes obesity, metabolic syndrome, diabetes, and cognitive decline. Their focus on the role of fructose seems premature due to confounding from energy and the heavy reliance on low quality evidence from animal models.
Vanessa Ha+10 more
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GLUT5 (SLC2A5) enables fructose-mediated proliferation independent of ketohexokinase
Background Fructose is an abundant source of carbon and energy for cells to use for metabolism, but only certain cell types use fructose to proliferate.
Roger J. Liang+14 more
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High-fructose corn syrup enhances intestinal tumor growth in mice
A sweetener's not-so-sweet effects Obesity increases an individual's risk of developing many types of cancer, including colorectal cancer. One of the factors driving the rise in obesity rates is thought to be the use of high-fructose corn syrup (HFCS) as
Marcus D. Goncalves+20 more
semanticscholar +1 more source
Effect of cyclosporine on hepatic energy status and on fructose metabolism after portacaval shunt in dog as monitored by phosphorus‐31 nuclear magnetic resonance spectroscopy in vivo [PDF]
The effect of cyclosporin A on the hepatic energy status and intracellular pH of the liver and its response to a fructose challenge has been investigated using in vivo phosphorus‐31 nuclear magnetic resonance spectroscopy in dogs.
Atkinson+37 more
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Protective Role of S-Adenosylmethionine Against Fructose-Induced Oxidative Damage in Obesity [PDF]
Introduction. It has been shown that S-adenosylmethionine (S-AMe) stimulates glutathione synthesis and increases cell resistance to the cytotoxic action of free radicals and pro-inflammatory cytokines. The aim of this study was to determine the effect of
Bratoeva, Kameliya Zh+3 more
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Fructose modulates cardiomyocyte excitation-contraction coupling and Ca²⁺ handling in vitro. [PDF]
BACKGROUND: High dietary fructose has structural and metabolic cardiac impact, but the potential for fructose to exert direct myocardial action is uncertain.
Kimberley M Mellor+5 more
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