Results 111 to 120 of about 2,549,001 (246)

Enzymatic Electrosynthesis for Sustainable CO2 Conversion: Advancing Circular Carbon Economy

Carbon Energy, EarlyView.
Enzymatic electrosynthesis (EES) offers molecular precision in synthesizing value‐added products from CO2. We highlight its distinct edge over alternative enzyme‐hybrid systems and analyze electron transfer pathways. Key strategies to overcome electron transfer bottlenecks and expand product diversity are addressed, and also data‐driven approaches for ...
Yan Xie, Jia Ouyang, Manu Suvarna, Xiangzhou Yuan, Matthew R. Hill, Uwe Bornscheuer, Huiyan Zhang, Yong Sik Ok   +7 more
wiley   +1 more source

Hot and Splicey: Kinesin Isoforms Seek Attention

Cytoskeleton, EarlyView.
ABSTRACT Kinesins family members (KIFs) are encoded in mammals by approximately 45 genes, which are grouped into 14 families based on structural and functional features. As cells increased in complexity, so too did the demand for specialized kinesin‐mediated processes, including intracellular transport, cytoskeletal organization, and cell division. One
C. Belhadi, M. A. Silverman
wiley   +1 more source

Genome-Wide Methylation and Gene Expression Changes in Newborn Rats following Maternal Protein Restriction and Reversal by Folic Acid. [PDF]

, 2013
A large body of evidence from human and animal studies demonstrates that the maternal diet during pregnancy can programme physiological and metabolic functions in the developing fetus, effectively determining susceptibility to later disease.
Irina G. Bogdarina (504027), Adrian J L Clark, Stupka, Elia, Langley-Evans Simon, Bogdarina, Irina, Stupka Elia, Altobelli, G, Gioia Altobelli (504026), Elia Stupka, Bogdarina, IG, Altobelli Gioia, Langley-Evans, Simon C., Simon Langley-Evans (367053), Langley-Evans, S, Gioia Altobelli, Bogdarina Irina G., Elia Stupka (23015), Clark, AJ, Clark Adrian J. L., Clark, Adrian J.C., Altobelli, Gioia, Simon Langley-Evans, Adrian J. L. Clark (367055), Irina G Bogdarina, Stupka, E   +24 more
core   +2 more sources

Expression Studies of the Obesity Candidate GeneFTOin Pig

Animal Biotechnology, 2009
Obesity is an increasing problem worldwide and research on candidate genes in good animal models is highly needed. The pig is an excellent model as its metabolism, organ size, and eating habits resemble that of humans. The present study is focused on the characterization of the fat mass and obesity associated gene (FTO) in pig.
Madsen, Majbritt Busk, Birck, Malene Muusfeldt, Fredholm, Merete, Cirera Salicio, Susanna   +3 more
openaire   +3 more sources

Pragmatic screening for autoimmune‐associated epilepsy in drug‐resistant epilepsy of unknown etiology in resource‐limited settings: A hypothesis‐generating study

Epileptic Disorders, EarlyView.
Abstract Objective To evaluate the feasibility of investigating autoimmune etiology in adults with drug‐resistant epilepsy (DRE) of unknown origin in resource‐limited settings and to develop a pragmatic, hypothesis‐generating screening approach to guide autoantibody testing. Methods A prospective observational study including adults with DRE of unknown
Tomásia O. de H. M. Frezatti, Ricardo L. Saute, Veriano Alexandre Júnior, Frederico N. Nakano, Marina T. R. P. Dalio, Tonicarlo R. Velasco, João P. Leite, Antônio Carlos dos Santos, Vanessa D. Marques, Américo C. Sakamoto   +9 more
wiley   +1 more source

Electrochemical Valence‐Regulated Biomimetic Nanozymes for Breast Cancer Metabolism Inhibition and Potentiated Catalytic Immunotherapy

Exploration, EarlyView.
MnOx nanozymes face low tumoricidal activity and PD‐L1‐mediated immune attenuation. Electrochemically regulated M‐MnOx with high oxidase activity was TCM‐wrapped into TMO. TMO targets tumors, triggers ICD, activates cGAS‐STING, antagonizes PD‐L1, and suppresses tumor recurrence, providing new insights for Mn‐based nanomaterials.
You Pan, Wei Cai, Meng Suo, Xiangqin Meng, Shengxin Ye, Yuping Tan, Xianqing Wei, Mingpu Yang, Pengyuan Qi, Zihang Yu, Kelong Fan, Shipeng Ning   +11 more
wiley   +1 more source

Genetic variation at the FTO locus influences RBL2 gene expression

, 2010
OBJECTIVE - Genome-wide association studies that compare the statistical association between thousands of DNA variations and a human trait have detected 958 loci across 127 different diseases and traits.
Carless, M., MacCluer, J., Blangero, J., Curran, J., Göring, H., Cole, S., Dyer, T., Moses, Eric, Johnson, M., Jowett, J., Comuzzie, A.   +10 more
core   +2 more sources

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Connexin 36 as a Regulator of Consummatory Behaviour [PDF]

, 2014
Gap junctions enable metabolic and electrical coupling of adjacent cells. Connexin 36 (Cx36) is a gap junction protein found predominantly in mammalian neurons.
Christian, David
core  

Investigation of a Patient With a Partial Trisomy 16q Including the Fat Mass and Obesity Associated Gene (FTO): Fine Mapping and FTO Gene Expression Study

, 2010
A female patient with a partial trisomy 16q was described previously. Her clinical characteristics included obesity, severe anisomastia, moderate to severe mental retardation, attention deficit hyperactivity disorder, dysmorphic facies, and contractions ...
Paul Eijk, Han, J.C., Maria Nesterova, Delemarre-van de Waa, H., Heutink, P., Linda van den Berg, Nesterova, M., Eijk, P., Henriette Delemarre‐van de Waal, Peter Heutink, Berg, L. van den, Ylstra, B., Waal, H.A. Delemarre-van d, Bauke Ylstra, Joan C. Han, Constantine A. Stratakis, Stratakis, C.A.   +16 more
core   +1 more source