Results 131 to 140 of about 7,322,114 (249)
Scientific Reports, 2019 Obesity is a well-known risk factor for multiple diseases including multiple sclerosis (MS). Polymorphisms in the fat-mass obesity (FTO) gene have been consistently found to be associated with obesity, and recently found to increase the risk of ...
Ahmad E. Al-Serri +2 more
semanticscholar +1 more source
Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.ABSTRACT Breast cancer, a malignant tumour that frightens women, ruthlessly claims the lives of tens of thousands of women around the world every year. However, the mechanism by which YTHDF3 regulates the occurrence and development of breast cancer is still imperfect.
ZiQian Liu +8 more
wiley +1 more source
Genetic Markers as Instrumental Variables:An Application to Child Fat Mass and Academic Achievement [PDF]
The use of genetic markers as instrumental variables (IV) is receiving increasing attention from economists. This paper examines the conditions that need to be met for genetic variants to be used as instruments.
Carol Propper +4 more
core +3 more sources
Expression Studies of the Obesity Candidate GeneFTOin Pig
Animal Biotechnology, 2009 Obesity is an increasing problem worldwide and research on candidate genes in good animal models is highly needed. The pig is an excellent model as its metabolism, organ size, and eating habits resemble that of humans. The present study is focused on the characterization of the fat mass and obesity associated gene (FTO) in pig.
Madsen, Majbritt Busk +3 more
openaire +3 more sources
Genes and Diseases, 2017 Obesity is a common disorder that has a significant impact on human health as it may lead to many serious diseases and sometimes morbidity. Previous genome-wide association studies (GWAS) confirmed that there is a relationship between some variants in ...
Samar Samir Abdelmajed +4 more
semanticscholar +1 more source
International Journal of General Medicine, 2020 Lubna Ibrahim Al Asoom,1 Dina Tariq Al Afandi,2 Aseel Salah Al Abdulhadi,3 Nazish Rafique,1 Shahanas Chathoth,4 Ahmad A Al Sunni1 1Physiology Department, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia; 2Pediatrics ...
Al Asoom LI +5 more
doaj
m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade [PDF]
, 2019 Melanoma is one of the most deadly and therapy-resistant cancers. Here we show that N6-methyladenosine (m6A) mRNA demethylation by fat mass and obesity-associated protein (FTO) increases melanoma growth and decreases response to anti-PD-1 blockade ...
Aplin, Andrew E. +10 more
core +1 more source
BMC Medical Genetics, 2017 BackgroundVariations within fat mass and obesity associated (FTO) gene had crosstalk with obesity risk in European and some Asian populations. This study was designed to investigate FTO rs9939609 association with metabolic syndrome (MetS) as well as ...
Mina S. Khella +3 more
semanticscholar +1 more source
Interaction between FTO gene variants and lifestyle factors on metabolic traits in an Asian Indian population [PDF]
, 2016 Background Lifestyle factors such as diet and physical activity have been shown to modify the association between fat mass and obesity–associated (FTO) gene variants and metabolic traits in several populations; however, there are no gene-lifestyle ...
AE Taylor +61 more
core +3 more sources
Acta Obstetricia et Gynecologica Scandinavica, 2015 Jaroslav A Hubacek +5 more
openaire +3 more sources