Results 121 to 130 of about 7,322,114 (249)
Hypothalamic FTO is associated with the regulation of energy intake not feeding reward
Background Polymorphism in the FTO gene is strongly associated with obesity, but little is known about the molecular bases of this relationship. We investigated whether hypothalamic FTO is involved in energy-dependent overconsumption of food.
Radomska Katarzyna J +7 more
doaj +1 more source
Dietary fat and total energy intake modifies the association of genetic profile risk score on obesity: evidence from 48 170 UK Biobank participants [PDF]
Background: Obesity is a multifactorial condition influenced by both genetics and lifestyle. The aim of this study was to investigate whether the association between a validated genetic profile risk score for obesity (GPRS-obesity) and body mass index ...
Anderson, Jana +13 more
core +1 more source
Interaction between the FTO gene, body mass index and depression: meta-analysis of 13701 individuals
Background Depression and obesity are highly prevalent, and major impacts on public health frequently co-occur. Recently, we reported that having depression moderates the effect of the FTO gene, suggesting its implication in the association between ...
M. Rivera +37 more
semanticscholar +1 more source
Despite significant advances, most academic research fails to result in medical products that benefit patients. This guide shares five key steps to help researchers close that gap: set clear goals, test thoroughly, protect ideas, build diverse teams, and partner with industry.
Cristina Oldani +4 more
wiley +1 more source
FTO gene variant modulates the neural correlates of visual food perception
Variations in the fat mass and obesity associated (FTO) gene are currently the strongest known genetic factor predisposing humans to non-monogenic obesity. Recent experiments have linked these variants to a broad spectrum of behavioural alterations, including food choice and substance abuse. Yet, the underlying neurobiological mechanisms by which these
Anne B. Kühn +7 more
openaire +4 more sources
Introduction The modifying effect of FTO gene expression level on change in body mass index and body composition has not been studied before. This study aimed to investigate the association between change in the expression level of the FTO gene and ...
S. Doaei +12 more
semanticscholar +1 more source
RNA Modifications: Current Understandings and Future Perspectives
Types of RNA modification. We have summarized the currently common types of RNA modifications, including ac4C, m6A, m1A, m5C, m3C, m7G, and ψ, and visually characterized their features through structural formulas. The characteristic structures are marked with a background color different from the background color.
Shiyu Xiao +7 more
wiley +1 more source
Purpose: The present study was carried out to investigate the association of fatty acid-binding protein 2 (FABP2) and fat mass and obesity-associated (FTO) gene polymorphism with primary open-angle glaucoma (POAG) cases and controls.
Shania Abbas +4 more
doaj +1 more source
The (fat mass and obesity associated) gene codes for a novel member of the non-heme dioxygenase superfamily [PDF]
This article is available from: http://www.biomedcentral.com/1471-2091/8/23[Background] Genetic variants in the FTO (fat mass and obesity associated) gene have been associated with an increased risk of obesity.
Andrade, Miguel A. +1 more
core +3 more sources
The fat mass and obesity-associated (FTO) gene has been shown to be associated with obesity in different populations. However, this association in the Chinese population has been controversial.
Zhiyong Dong +6 more
doaj +1 more source

