Results 141 to 150 of about 7,322,114 (249)

Oxidative stress-mediated activation of FTO exacerbates impairment of the epithelial barrier by up-regulating IKBKB via N6-methyladenosine-dependent mRNA stability in asthmatic mice exposed to PM2.5

Ecotoxicology and Environmental Safety
In order to comprehend the underlying mechanisms contributing to the development and exacerbation of asthma resulting from exposure to fine particulate matter (PM2.5), we established an asthmatic model in fat mass and obesity-associated gene knockdown ...
Anying Xiong, Xiang He, Shengbin Liu, Qin Ran, Lei Zhang, Junyi Wang, Manling Jiang, Bin Niu, Ying Xiong, Guoping Li   +9 more
doaj   +1 more source

Polimorfismo del alelo rs 9939609 en el gen FTO como factor de riesgo para el desarrollo de sobrepeso en niños ecuatorianos en edad pre-escolar [PDF]

, 2017
Obesity and overweight are diseases that have being increasing exponentially in the last years worldwide. There are environmental and genetic factors involved with the development and evolution of this condition.
Cabezas Reyes, María Cristina
core  

The FTO Gene and Measured Food Intake in 5‐ to 10‐Year‐Old Children Without Obesity

Obesity, 2019
Genetic variation in the first intron of FTO (e.g., single‐nucleotide polymorphism [SNP] rs9939609) is strongly associated with adiposity. This effect is thought to be mediated (at least in part) via increasing caloric intake, although the precise ...
L. Ranzenhofer, Laurel Mayer, Haley Davis, Hanna K. Mielke‐Maday, Hailey J McInerney, Rachel Korn, Nikita Gupta, A. Brown, J. Schebendach, M. Tanofsky-Kraff, V. Thaker, Wendy K. Chung, R. Leibel, B. Walsh, M. Rosenbaum   +14 more
semanticscholar   +1 more source

Association study of FTO gene single nucleotide polymorphism rs9939609 with body mass and oral microbiome in women from the Zagreb Region [PDF]

, 2016
Pretilost je rastući problem diljem svijeta. Nastaje kao posljedica kronične neravnoteže unosa i potrošnje energije. Etiologija pretilosti je vrlo složena, a procjenjuje se da su genetičke razlike među pojedincima uzrok 40 – 70% razlike u sklonosti ...
Škara, Lucija
core   +1 more source

Assessment of the FTO gene polymorphisms (rs1421085, rs17817449 and rs9939609) in exercise-trained men and women: the effects of a 4-week hypocaloric diet

Journal of the International Society of Sports Nutrition, 2019
BackgroundVariations in the fat mass and obesity-associated gene (FTO) are associated with obesity; however, it is unclear if changes in energy intake affect the adaptive response to caloric restriction in those with risk variants.
J. Antonio, S. Knafo, Madaline Kenyon, A. Ali, Cassandra Carson, Anya Ellerbroek, Cailey Weaver, Justin D Roberts, C. Peacock, Jaime L Tartar   +9 more
semanticscholar   +1 more source

Empirical Bayesian Approach to Testing Multiple Hypotheses with Separate Priors for Left and Right Alternatives [PDF]

, 1999
We consider a multiple hypotheses problem with directional alternatives in a decision theoretic framework. We obtain an empirical Bayes rule subject to a constraint on mixed directional false discovery rate (mdFDR≤α) under the semiparametric setting ...
Bansal, Naveen K., Maadooliat, Mehdi, Schrodi, Steven J.   +2 more
core   +1 more source

Association between Fat Mass and Obesity Associated (FTO) gene polymorphism (rs9939609) and lipid profile in type 2 diabetic obese Iraqi male

Iraq Medical Journal, 2018
Objective Investigation the risk of allele frequency of FTO gene polymorphism rs9939609 in obese male with type 2 diabetes mellitus (T2DM) and to examine the association of this polymorphism of FTO gene with BMI and lipid profile in obese Iraqi male ...
Fadhil Jawad Al-Tu’ma, Khamail Hassan Obed   +1 more
doaj  

Involvement of the FTO A > T polymorphism in body composition and lipid profile changes after aerobic training in adults with overweight and obesity

Diabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 4361-4365, May 2026.
Herik Fonseca, Glebia Cardoso, George Araújo, Eriklys Barreto, Mateus Ribeiro, Ana Pereira, Cecília Marinho, Bruno Sousa, Victor Ferreira, Lydiane Toscano, Raquel Silva, Thais Assis, Darlene Persuhn, Alexandre Silva   +13 more
wiley   +1 more source

FTO Gene Associates and Interacts with Obesity Risk, Physical Activity, Energy Intake, and Time Spent Sitting: Pilot Study in a Nigerian Population

Journal of Obesity, 2017
Fat mass and obesity-associated (FTO) gene influences obesity but studies have shown that environmental/lifestyle variables like physical activity (PA), time spent sitting (TSS), and energy intake might mediate the effect.
Bolaji Fatai Oyeyemi, Charles Ayorinde Ologunde, Ayonposi Bukola Olaoye, Nanfizat Abiket Alamukii   +3 more
doaj   +1 more source

Intellectual Property Management in Health and Agricultural Innovation: Executive Guide [PDF]

, 2007
Prepared by and for policy-makers, leaders of public sector research establishments, technology transfer professionals, licensing executives, and scientists, this online resource offers up-to-date information and strategies for utilizing the power of ...
Bennett, Alan B., Fernandez, Carlos, Graff, Gregory D., Kowalski, Stanley, Krattiger, Anatole, Mahoney, Richard T., Nelsen, Lita, Satyanarayana, Kanikaram, Thomson, Jennifer A.   +8 more
core   +2 more sources