Results 141 to 150 of about 15,826 (205)

Association of the FTO gene polymorphism with the features of the clinical course of tuberculosis infection. [PDF]

BMC Infect Dis
Zhang J, Wang MJ, Jiang F, He JQ.
europepmc   +1 more source

Beyond a Metabolite: Lactylation as a Pivotal Regulator of Colorectal Cancer Pathogenesis and Treatment Resistance

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
This review elucidates how lactylation, a novel histone modification driven by lactate, regulates colorectal cancer pathogenesis. We summarize its roles in tumor progression, metastasis, stemness, immunosuppression, and therapy resistance, and discusses the promising therapeutic strategies of targeting the lactylation pathway.
Shuilan Yao, Yun Liang, Xinwen Liang, Qisheng Su, Xiaohong Li   +4 more
wiley   +1 more source

Effects of FTO Gene rs9939609 and rs17817449 Polymorphisms on Insulin Resistance in Turkish Children With Obesity. [PDF]

J Diabetes
Köksal M, Ünlü Söğüt M, Kabalı S.
europepmc   +1 more source

Targeted metabolomics suggests a probable role of the FTO gene in the kynurenine pathway in prediabetes. [PDF]

PeerJ, 2022
Chailurkit LO, Chanprasertyothin S, Thongmung N, Sritara P, Ongphiphadhanakul B.   +4 more
europepmc   +1 more source

Construction of an O2‐responsive engineering bioreactor for enhanced indole‐3‐propionic acid production and deoxynivalenol detoxification

Responsive Materials, Volume 4, Issue 3, August 2026.
An oxygen‐responsive living bioreactor was engineered via interspecies protoplast fusion, converting oxygen from an inhibitory stress into a programmable signal for sustained indole‐3‐propionic acid (IPA) production. This genetically encoded bioreactor enables robust aerobic operation and therapeutic efficacy of deoxynivalenol detoxification in vivo ...
Ning Ma, Jiakun Shen, Kun Cai, Wenxi Zhao, Chuan Feng, Xingyao Wang, Yangyang Liu, Dongyan Zhang, Xi Ma   +8 more
wiley   +1 more source

Impact of fat mass and obesity-associated (FTO) gene variants on adult obesity and overweight: a comprehensive meta-analysis. [PDF]

BMC Endocr Disord
Eghbali M, Iranmanesh M, Hatami N, Mobaderi T, Ghadikolaei OA, Cheraghi S.   +5 more
europepmc   +1 more source

Is FTO a type 2 diabetes susceptibility gene? [PDF]

Diabetologia, 2012
openaire   +2 more sources

PACS2 at Mitochondria‐Associated Membranes: A Central Regulator of Cardiovascular and Metabolic Diseases

Journal of Cellular and Molecular Medicine, Volume 30, Issue 16, August 2026.
ABSTRACT Cardiovascular and metabolic diseases (CVMDs), which are characterized by metabolic dysregulation and cardiovascular impairment, constitute a major global cause of mortality, thus highlighting the urgent need for novel therapeutic strategies. Phosphofurin acidic cluster sorting protein 2 (PACS2), a multifunctional adapter protein localized to ...
Baiyi Tang, Hui Wang, Jie Ouyang
wiley   +1 more source

Association of fetal FTO gene variants with maternal postload glucose levels in pregnancy. [PDF]

Int J Obes (Lond)
Firneisz G, Nádasdi Á, Nemes BA, Németh L, Rosta K, Harreiter J, Kautzky-Willer A, Somogyi A, Benyó Z.   +8 more
europepmc   +1 more source

Type 2 diabetes linked FTO gene variant rs8050136 is significantly associated with gravidity in gestational diabetes in a sample of Bangladeshi women: Meta-analysis and case-control study. [PDF]

PLoS One, 2023
Amin USM, Rahman TA, Hasan M, Tofail T, Hasanat MA, Seraj ZI, Salimullah M.   +6 more
europepmc   +1 more source