Results 141 to 150 of about 2,549,001 (246)
Introdução: O número de indivíduos com sobrepeso e obesidade está aumentando, e a busca por entender mecanismo relacionados a esta doença se mostram cada vez mais importantes.
Moraes, Vitor Nolasco de
core +1 more source
ABSTRACT Background Obesity's global rise has outpaced the effectiveness of “one‐size‐fits‐all” prevention and treatment strategies. The promise of precision medicine lies in addressing the etiological and biological diversity of obesity and transforming it into actionable endotypes.
Nadia Abu Samra +13 more
wiley +1 more source
ABSTRACT Mediation analysis identifies variables that explain the causal pathways linking an exposure (here genetic susceptibility to obesity) to an outcome (here obesity‐related traits), offering potential targets for weight management interventions.
Benoît Boulanger +5 more
wiley +1 more source
Understanding Exosomes in Hair Regeneration
Abstract Background Alopecia is a prevalent condition correlated with significant psychosocial challenges, while contemporary treatments exhibit variable efficacy, require extended use, and may cause adverse effects. This review aimed to comprehensively assess exosome‐mediated interventions as a novel cell‐free regenerative approach for hair ...
Paras Ahmad +3 more
wiley +1 more source
The role of FTO genotype in the effect of FTO gene expression level on change in body mass index and body composition has not been studied. This study aimed to investigate the role of FTO genotype in the association between change in the expression level
Gholamalizadeh, M. (Maryam) +12 more
core
Understanding extracellular vesicles in antiaging
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad +3 more
wiley +1 more source
Association of Genetic Polymorphisms in the Human FTO Gene and Obesity: Systematic Review and Meta-Analysis [PDF]
The aim of the study is to perform a systematic review and meta-analysis to determine whether the Fat Mass and Obesity-associated (FTO) polymorphisms influenced obesity and which Single Nucleotide Polymorphisms (SNPs) raised the risk of obesity.
Md Nor, Norazmir +4 more
core +1 more source
Crosstalk between FTO gene polymorphism (rs9939609) and obesity-related traits among Bangladeshi population. [PDF]
Shill LC, Alam MR.
europepmc +1 more source
Hypoxia and hypercapnia elicit overlapping but distinct skeletal muscle toxicities
Abstract figure legend Hypoxia and hypercapnia cause overlapping skeletal muscle phenotypes, including atrophy, change in myofibre metabolic profile and myogenic response to injury. Both signals operate via distinct cellular pathways. Abstract Skeletal muscle dysfunction is strongly associated with elevated mortality in acute and chronic pulmonary ...
Joseph Balnis, Ariel Jaitovich
wiley +1 more source

