Results 11 to 20 of about 63,826 (347)
The trypanosomatid protozoan parasite Leishmania has a significant impact on human health globally. Understanding the pathways associated with virulence within this significant pathogen is critical for identifying novel vaccination and chemotherapy ...
Gloria Polanco +3 more
doaj +1 more source
Intestinal stem cells (ISCs) are critical for the development and rapid turnover of intestinal epithelium. The regulatory effects of gut microbiota and their metabolites on ISCs stemness remain elusive.
Caihan Duan +7 more
doaj +1 more source
Effects of L-fucose supplementation on the viability of cancer cell lines
Background: Fucose is a deoxyhexose sugar. While the biological roles of L-fucose remain unclear, the sugar is known to accelerate the malignant potential of cancer cells.
Muhammad Alif Mazlan +2 more
doaj +1 more source
Developing a Fluorescent Inducible System for Free Fucose Quantification in Escherichia coli
L-Fucose is a monosaccharide abundant in mammalian glycoconjugates. In humans, fucose can be found in human milk oligosaccharides (HMOs), mucins, and glycoproteins in the intestinal epithelium.
Samantha Nuñez +2 more
doaj +1 more source
Mutations in the SLC35C1 gene encoding the Golgi GDP-fucose transporter are known to cause leukocyte adhesion deficiency II. However, improvement of fucosylation in leukocyte adhesion deficiency II patients treated with exogenous fucose suggests the existence of an SLC35C1-independent route of GDP-fucose transport, which remains a mystery.
Edyta Skurska +6 more
openaire +2 more sources
Background: Lack of noninvasive and economically feasible laboratory investigations in the early detection of cancer is a set-back in the prognosis of oral cancer (OC) patients.
Anandhi Sekar Arthisri +3 more
doaj +1 more source
Pathogenic Variants in Fucokinase Cause a Congenital Disorder of Glycosylation [PDF]
FUK encodes fucokinase, the only enzyme capable of converting L-fucose to fucose-1-phosphate, which will ultimately be used for synthesizing GDP-fucose, the donor substrate for all fucosyltransferases.
Bearden, David R. +9 more
core +1 more source
The role of the mobile proton in fucose migration [PDF]
Fucose migration reactions represent a substantial challenge in the analysis of fucosylated glycan structures by mass spectrometry. In addition to the well-established observation of transposed fucose residues in glycan-dissociation product ions, recent ...
Helden, Gert von +7 more
core +1 more source
Metabolomic and Transcriptomic Analyses of Escherichia coli for Efficient Fermentation of L-Fucose
L-Fucose, one of the major monomeric sugars in brown algae, possesses high potential for use in the large-scale production of bio-based products. Although fucose catabolic pathways have been enzymatically evaluated, the effects of fucose as a carbon ...
Jungyeon Kim +3 more
doaj +1 more source
Assessment of serum fucose level among oral squamous cell carcinoma patients: A case-control study
Background: Serum glycoproteins, which are made up of various monosaccharides, are altered in malignancy, a disorder of cellular conduct. L-fucose, a methyl pentose that serves as the last sugar in the majority of plasma glycoproteins, is one of the ...
Albert Ashem +5 more
doaj +1 more source

