Results 11 to 20 of about 61,412 (311)
Untersuchungen über die Fucose [PDF]
Berichte der deutschen chemischen Gesellschaft, 1907 n ...
Mayer, Willy, Tollens, B.
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The Metabolism of l-Fucose [PDF]
Journal of Biological Chemistry, 1968 Abstract Guanosine diphosphate l-fucose pyrophosphorylase was purified approximately 46-fold from extracts of porcine liver. The purified enzyme was specific for guanosine triphosphate and l-fucose 1-phosphate, and exhibited a requirement for magnesium ions. The partially purified pyrophosphorylase preparation was used to prepare an l-fucose-containing
Edward C. Heath, Hanako Ishihara
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Developing a Fluorescent Inducible System for Free Fucose Quantification in Escherichia coli
Biosensors, 2023 L-Fucose is a monosaccharide abundant in mammalian glycoconjugates. In humans, fucose can be found in human milk oligosaccharides (HMOs), mucins, and glycoproteins in the intestinal epithelium.
Samantha Nuñez +2 more
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The Threonine That Carries Fucose, but Not Fucose, Is Required for Cripto to Facilitate Nodal Signaling [PDF]
Journal of Biological Chemistry, 2007 Cripto is a membrane-bound co-receptor for Nodal, a member of the transforming growth factor-beta superfamily. Mouse embryos lacking either Cripto or Nodal have the same lethal phenotype at embryonic day 7.5. Previous studies suggest that O-fucosylation of the epidermal growth factor-like (EGF) repeat in Cripto is essential for the facilitation of ...
Pamela Stanley +5 more
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Frontiers in Cellular and Infection Microbiology, 2023 IntroductionPrevious studies reported that fucose plays a protective role in inhibiting pathogens. Fusobacterium nucleatum (Fn) was recently found to promote the progression of colitis. However, the effects of fucose on Fn are poorly understood.
Caihan Duan +6 more
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Microbiology Spectrum, 2022 The trypanosomatid protozoan parasite Leishmania has a significant impact on human health globally. Understanding the pathways associated with virulence within this significant pathogen is critical for identifying novel vaccination and chemotherapy ...
Gloria Polanco +3 more
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Fucose, placental evolution and the glycocode [PDF]
Glycobiology, 2011 A family of 13 fucosyltransferase genes has evolved to catalyze the addition of fucose in various linkage positions to nascent glycoproteins. Null mutations in mice are unearthing unsuspected functions for glycoprotein fucosylation that affect embryo implantation and growth of the conceptus.
Aplin, John, Jones, Carolyn JP
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Biological functions of fucose in mammals [PDF]
Glycobiology, 2017 Fucose is a 6-deoxy hexose in the l-configuration found in a large variety of different organisms. In mammals, fucose is incorporated into N-glycans, O-glycans and glycolipids by 13 fucosyltransferases, all of which utilize the nucleotide-charged form, GDP-fucose, to modify targets. Three of the fucosyltransferases, FUT8, FUT12/POFUT1 and FUT13/POFUT2,
Michael Schneider +4 more
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Effects of L-fucose supplementation on the viability of cancer cell lines
Makara Journal of Health Research, 2020 Background: Fucose is a deoxyhexose sugar. While the biological roles of L-fucose remain unclear, the sugar is known to accelerate the malignant potential of cancer cells.
Muhammad Alif Mazlan +2 more
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Pathogenic Variants in Fucokinase Cause a Congenital Disorder of Glycosylation [PDF]
, 2018 FUK encodes fucokinase, the only enzyme capable of converting L-fucose to fucose-1-phosphate, which will ultimately be used for synthesizing GDP-fucose, the donor substrate for all fucosyltransferases.
Bearden, David R. +9 more
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