Results 21 to 30 of about 41,130 (245)
Microbiology Spectrum, 2022 The trypanosomatid protozoan parasite Leishmania has a significant impact on human health globally. Understanding the pathways associated with virulence within this significant pathogen is critical for identifying novel vaccination and chemotherapy ...
Gloria Polanco +3 more
doaj +1 more source
Effects of L-fucose supplementation on the viability of cancer cell lines
Makara Journal of Health Research, 2020 Background: Fucose is a deoxyhexose sugar. While the biological roles of L-fucose remain unclear, the sugar is known to accelerate the malignant potential of cancer cells.
Muhammad Alif Mazlan +2 more
doaj +1 more source
Gut Microbes, 2023 Intestinal stem cells (ISCs) are critical for the development and rapid turnover of intestinal epithelium. The regulatory effects of gut microbiota and their metabolites on ISCs stemness remain elusive.
Caihan Duan +7 more
doaj +1 more source
Developing a Fluorescent Inducible System for Free Fucose Quantification in Escherichia coli
Biosensors, 2023 L-Fucose is a monosaccharide abundant in mammalian glycoconjugates. In humans, fucose can be found in human milk oligosaccharides (HMOs), mucins, and glycoproteins in the intestinal epithelium.
Samantha Nuñez +2 more
doaj +1 more source
Contemporary Clinical Dentistry, 2020 Background: Lack of noninvasive and economically feasible laboratory investigations in the early detection of cancer is a set-back in the prognosis of oral cancer (OC) patients.
Anandhi Sekar Arthisri +3 more
doaj +1 more source
Metabolomic and Transcriptomic Analyses of Escherichia coli for Efficient Fermentation of L-Fucose
Marine Drugs, 2019 L-Fucose, one of the major monomeric sugars in brown algae, possesses high potential for use in the large-scale production of bio-based products. Although fucose catabolic pathways have been enzymatically evaluated, the effects of fucose as a carbon ...
Jungyeon Kim +3 more
doaj +1 more source
mBio, 2020 The opportunistic bacterium Pseudomonas aeruginosa produces the fucose-specific lectin LecB, which has been identified as a virulence factor. LecB has a tetrameric structure with four opposing binding sites and has been shown to act as a cross-linker ...
Roland Thuenauer +10 more
doaj +1 more source
Cellular Fucosylation Inhibitors Based on Fluorinated Fucose-1-Phosphates [PDF]
, 2020 Fucosylation of glycans impacts a myriad of physiological and pathological processes. Inhibition of fucose expression emerges as a potential therapeutic avenue for example in cancer, inflammation, and infection.
Marek, Noga +7 more
core +2 more sources
Fucose-Functionalized Precision Glycomacromolecules Targeting Human Norovirus Capsid Protein
, 2018 Norovirus infection is the major cause of nonbacterial gastroenteritis in humans and has been the subject of numerous studies investigating the virus’s biophysical properties and biochemical function with the aim of deriving novel and highly potent entry
Alvaro Mallagaray +31 more
core +2 more sources
Frontiers in Microbiology, 2020 Inflammatory bowel disease is associated with intestinal dysbiosis and with elevated antibody production toward microbial epitopes. The underlying processes linking the gut microbiota with inflammation are still unclear.
Katharina Kappler +4 more
doaj +1 more source