Results 11 to 20 of about 60,769 (251)
Journal of Biological Chemistry, 2022 Mutations in the SLC35C1 gene encoding the Golgi GDP-fucose transporter are known to cause leukocyte adhesion deficiency II. However, improvement of fucosylation in leukocyte adhesion deficiency II patients treated with exogenous fucose suggests the existence of an SLC35C1-independent route of GDP-fucose transport, which remains a mystery.
Edyta Skurska +6 more
openaire +2 more sources
Contemporary Clinical Dentistry, 2020 Background: Lack of noninvasive and economically feasible laboratory investigations in the early detection of cancer is a set-back in the prognosis of oral cancer (OC) patients.
Anandhi Sekar Arthisri +3 more
doaj +1 more source
Pathogenic Variants in Fucokinase Cause a Congenital Disorder of Glycosylation [PDF]
, 2018 FUK encodes fucokinase, the only enzyme capable of converting L-fucose to fucose-1-phosphate, which will ultimately be used for synthesizing GDP-fucose, the donor substrate for all fucosyltransferases.
Bearden, David R. +9 more
core +1 more source
Metabolomic and Transcriptomic Analyses of Escherichia coli for Efficient Fermentation of L-Fucose
Marine Drugs, 2019 L-Fucose, one of the major monomeric sugars in brown algae, possesses high potential for use in the large-scale production of bio-based products. Although fucose catabolic pathways have been enzymatically evaluated, the effects of fucose as a carbon ...
Jungyeon Kim +3 more
doaj +1 more source
Roles of Predicted Glycosyltransferases in the Biosynthesis of the Rhizobium etli CE3 O Antigen [PDF]
, 2013 The Rhizobium etli CE3 O antigen is a fixed-length heteropolymer. The genetic regions required for its synthesis have been identified, and the nucleotide sequences are known.
Noel, K. Dale +2 more
core +2 more sources
Assessment of serum fucose level among oral squamous cell carcinoma patients: A case-control study
Journal of Pharmacy and Bioallied Sciences, 2023 Background: Serum glycoproteins, which are made up of various monosaccharides, are altered in malignancy, a disorder of cellular conduct. L-fucose, a methyl pentose that serves as the last sugar in the majority of plasma glycoproteins, is one of the ...
Albert Ashem +5 more
doaj +1 more source
mBio, 2020 The opportunistic bacterium Pseudomonas aeruginosa produces the fucose-specific lectin LecB, which has been identified as a virulence factor. LecB has a tetrameric structure with four opposing binding sites and has been shown to act as a cross-linker ...
Roland Thuenauer +10 more
doaj +1 more source
Frontiers in Microbiology, 2020 Inflammatory bowel disease is associated with intestinal dysbiosis and with elevated antibody production toward microbial epitopes. The underlying processes linking the gut microbiota with inflammation are still unclear.
Katharina Kappler +4 more
doaj +1 more source
PLoS ONE, 2018 The fucose salvage pathway is a two-step process in which mammalian cells transform L-fucose into GDP-L-fucose, a universal fucose donor used by fucosyltransferases to modify glycans.
Tyler Keeley +4 more
doaj +1 more source
Std fimbriae-fucose interaction increases Salmonella-induced intestinal inflammation and prolongs colonization [PDF]
, 2019 Author summary The intestinal epithelium is a crucial biological interface, interacting with both commensal and pathogenic microorganisms. It’s lined with heavily glycosylated proteins and glycolipids which can act as both attachment sites and energy ...
Baines, J. +12 more
core +1 more source