L-fucose administration ameliorates chronic social defeat stress-induced depressive-like behaviors by restoring GDP-fucose biosynthetic activation and core fucosylation [PDF]
Frontiers in ImmunologyChronic psychosocial stress is a major driver of depression, yet the glycometabolic mechanisms linking stress exposure to neuroinflammation and synaptic dysfunction remain poorly understood.
Meng Zheng +13 more
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Fucose migration: where to ? [PDF]
, 2022 Fucose is a ubiquitous monosaccharide linked to the core of major classes of glycans and the identification of fucose location is one critical bottleneck in glycomics. This is due to the remarkable inclination of the fucosyl residue to migrate to neighboring throughout mass spectrometric analysis.
Baptiste Moge +3 more
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Protein oxidation of fucose environments (POFE) reveals fucose–protein interactions [PDF]
Chemical SciencePOFE (Protein Oxidation of Fucose Environments) method utilizes proximity-based oxidative proteomics to decipher cellular fucosylated glycoprotein interactions.
Yixuan Xie +6 more
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Structure of the fucose mutarotase fromStreptococcus pneumoniaein complex with
Acta Crystallographica Section F Structural Biology and Crystallization Communications, 2011 Streptococcus pneumoniaerelies on a variety of carbohydrate-utilization pathways for both colonization of its human host and full virulence during the development of invasive disease. One such pathway is the fucose-utilization pathway, a component of which is fucose mutarotase (SpFcsU), an enzyme that performs the interconversion between α-L-fucose and
Melanie A, Higgins, Alisdair B, Boraston
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Mode of Molecular Recognition of l-Fucose by Fucose-Binding Legume Lectins
Biochemical and Biophysical Research Communications, 2000 Recognition of cell surface carbohydrate moieties by lectins plays a vital role in many a biological process. Fucosyated residues are often implicated as key recognition markers in many cellular processes. In particular, the aspects of molecular recognition of fucose by fucose-bindinglectins UEA 1 and LTA pose a special case because no crystal ...
Thomas, Celestine J, Surolia, Avadhesha
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Enhanced Quality and Metabolic Profile of Fermented Milk Through Fucose Supplementation with Lactobacillus helveticus [PDF]
MoleculesFermented milk represents an excellent carrier for probiotics, and the incorporation of different carbon sources during fermentation can profoundly affect microbial metabolism.
Shunyu Wang +6 more
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Campylobacter jejuni uses energy taxis and a dehydrogenase enzyme for l-fucose chemotaxis
mBio, 2023 Campylobacter jejuni is a leading cause of bacterial diarrhea worldwide, and infection in infants is associated with growth stunting in low- and middle-income countries. Approximately half of all C. jejuni isolates are asaccharolytic, while the remainder
Bibi Zhou +6 more
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Rational design of GDP‑d‑mannose mannosyl hydrolase for microbial l‑fucose production
Microbial Cell Factories, 2023 Background l‑Fucose is a rare sugar that has beneficial biological activities, and its industrial production is mainly achieved with brown algae through acidic/enzymatic fucoidan hydrolysis and a cumbersome purification process.
Cong Fu +9 more
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Production of perdeuterated fucose from glyco-engineered bacteria [PDF]
, 2020 L-Fucose and L-fucose-containing polysaccharides, glycoproteins or glycolipids play an important role in a variety of biological processes. L-Fucose-containing glycoconjugates have been implicated in many diseases including cancer and rheumatoid ...
Forsyth, V Trevor, Trevor +6 more
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Frontiers in Cellular and Infection Microbiology, 2023 IntroductionPrevious studies reported that fucose plays a protective role in inhibiting pathogens. Fusobacterium nucleatum (Fn) was recently found to promote the progression of colitis. However, the effects of fucose on Fn are poorly understood.
Caihan Duan +6 more
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