Results 21 to 30 of about 63,826 (347)

miRNAs as Regulators of Antidiabetic Effects of Fucoidans [PDF]

, 2019
open access articleDiabetes mellitus is a metabolic disease with a high mortality rate worldwide. MicroRNAs (miRNAs), and other small noncoding RNAs, serve as endogenous gene regulators through binding to specific sequences in RNA and modifying gene ...
Arroo, R. R. J., El-Seed, Hesham, Ismail, Amin, Lai, Shanshan, Liu, Dan, Wu, Desheng, Xiao, Jianbo, Zhao, Chao, Zou, Xiaobo   +8 more
core   +1 more source

Roles of Predicted Glycosyltransferases in the Biosynthesis of the Rhizobium etli CE3 O Antigen [PDF]

, 2013
The Rhizobium etli CE3 O antigen is a fixed-length heteropolymer. The genetic regions required for its synthesis have been identified, and the nucleotide sequences are known.
Noel, K. Dale, Ojeda, Kristylea J., Simonds, Laurie   +2 more
core   +2 more sources

The Pseudomonas aeruginosa Lectin LecB Causes Integrin Internalization and Inhibits Epithelial Wound Healing

mBio, 2020
The opportunistic bacterium Pseudomonas aeruginosa produces the fucose-specific lectin LecB, which has been identified as a virulence factor. LecB has a tetrameric structure with four opposing binding sites and has been shown to act as a cross-linker ...
Roland Thuenauer, Alessia Landi, Anne Trefzer, Silke Altmann, Sarah Wehrum, Thorsten Eierhoff, Britta Diedrich, Jörn Dengjel, Alexander Nyström, Anne Imberty, Winfried Römer   +10 more
doaj   +1 more source

Increased Antibody Response to Fucosylated Oligosaccharides and Fucose-Carrying Bacteroides Species in Crohn’s Disease

Frontiers in Microbiology, 2020
Inflammatory bowel disease is associated with intestinal dysbiosis and with elevated antibody production toward microbial epitopes. The underlying processes linking the gut microbiota with inflammation are still unclear.
Katharina Kappler, Yi Lasanajak, David F. Smith, Lennart Opitz, Thierry Hennet   +4 more
doaj   +1 more source

Detection of Bacterial α-l-Fucosidases with an Ortho-Quinone Methide-Based Probe and Mapping of the Probe-Protein Adducts

Molecules, 2022
Fucosidases are associated with several pathological conditions and play an important role in the health of the human gut. For example, fucosidases have been shown to be indicators and/or involved in hepatocellular carcinoma, breast cancer, and ...
Yvette M. C. A. Luijkx, Anniek J. Henselijn, Gerlof P. Bosman, Dario A. T. Cramer, Koen C. A. P. Giesbers, Esther M. van ‘t Veld, Geert-Jan Boons, Albert J. R. Heck, Karli R. Reiding, Karin Strijbis, Tom Wennekes   +10 more
doaj   +1 more source

Glycan analysis of the chicken synaptic plasma membrane glycoproteins - a major synaptic N-glycan carries the LewisX determinant [PDF]

, 2005
The majority of plasma membrane components are glycosylated. It is now widely accepted that this post-translational modification is crucial during the establishment, maintenance and function of the nervous system.
Koles, Kate, McDowell, William, Mileusnic, Radmila, Rose, Steven P.R.   +3 more
core   +4 more sources

Regulatory activity revealed by dynamic correlations in gene expression noise [PDF]

, 2008
Gene regulatory interactions are context dependent, active in some cellular states but not in others. Stochastic fluctuations, or 'noise', in gene expression propagate through active, but not inactive, regulatory links^(1,2).
Cox, Robert Sidney, III, Dunlop, Mary J., Elowitz, Michael B., Levine, Joseph H., Murray, Richard M.   +4 more
core   +2 more sources

Fucose as a nutrient ligand for Dikarya and a building block of early diverging lineages

IMA Fungus, 2023
Fucose is a deoxyhexose sugar present and studied in mammals. The process of fucosylation has been the primary focus in studies relating to fucose in animals due to the presence of fucose in Lewis antigens.
Małgorzata Orłowska, Drishtee Barua, Sebastian Piłsyk, Anna Muszewska   +3 more
doaj   +1 more source

In Silico and In Vitro Investigation of the Distribution and Expression of Key Genes in the Fucose Operon of Escherichia coli

Microorganisms, 2023
Many gut bacteria degrade polysaccharides, providing nutritional advantages to their hosts. Fucose, a mucin degradation product, was suggested as a communication molecule between the resident microbiota and external pathogens.
Nehal A. Saif, Yomna A. Hashem, Heba M. Amin, Ramy K. Aziz   +3 more
doaj   +1 more source

Fucose-Containing Sulfated Polysaccharides from Brown Seaweeds Inhibit Proliferation of Melanoma Cells and Induce Apoptosis by Activation of Caspase-3 in Vitro

Marine Drugs, 2011
Fucose-containing sulfated polysaccharides (FCSPs) extracted from seaweeds, especially brown macro-algae, are known to possess essential bioactive properties, notably growth inhibitory effects on tumor cells.
Anne S. Meyer, Jørn D. Mikkelsen, Marcel Tutor Ale, Hidekazu Tamauchi, Hiroko Maruyama   +4 more
doaj   +1 more source