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Sulfated polysaccharide from <i>Phyllophorella kohkutiensis</i>: Extraction, purification, and bioactivity assessment. [PDF]
Aramsangtienchai P +6 more
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Novel insights into the host cell glycan binding profile of human metapneumovirus. [PDF]
Van Den Bergh A +4 more
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Fucosylated chondroitin sulfate diversity in sea cucumbers: A review
Carbohydrate Polymers, 2014Fucosylated chondroitin sulfate (FucCS) is structurally distinct glycosaminoglycans found from the sea cucumber body wall consisted of chondroitin sulfate type backbone with attached sulfated or non-sulfated fucose side chain. Structurally this compound plays an important role in maintaining the body wall integrity and possesses a wide spectrum of ...
Pang Myron +2 more
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Carbohydrate Polymers, 2021
Sea cucumbers were nutritional food and traditional Chinese medicine. In this study, fucosylated chondroitin sulfate from sea cucumber Stichopus chloronotus (fCS-Sc), a potential anticoagulant agent and immunological adjuvant, was investigated for its immune activation effects on RAW 264.7 macrophage for the first time.
Shuxin, Jiang +6 more
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Sea cucumbers were nutritional food and traditional Chinese medicine. In this study, fucosylated chondroitin sulfate from sea cucumber Stichopus chloronotus (fCS-Sc), a potential anticoagulant agent and immunological adjuvant, was investigated for its immune activation effects on RAW 264.7 macrophage for the first time.
Shuxin, Jiang +6 more
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The structure of a fucosylated chondroitin sulfate from the sea cucumber Cucumaria frondosa
Carbohydrate Polymers, 2017A fucosylated chondroitin sulfate (FCS) CF was isolated from the sea cucumber Cucumaria frondosa and purified by anion-exchange chromatography. Chemical and NMR spectroscopic methods were applied for the structural characterization of this biopolymer. The backbone of CF was found to consist of chondroitin sulfate A and E fragments together with rather ...
Nadezhda E, Ustyuzhanina +5 more
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Carbohydrate Polymers, 2016
This study aimed at investigating the chain conformation and physicochemical properties of fucosylated chondroitin sulfate extracted from sea cucumber Apostichopus japonicas (Aj-fCS). By using HPSEC-MALLS-Visc-RI, Mw, z(1/2), Rh and [η] for Aj-fCS were determined as 58.0±4.4kDa, 21.8±1.3nm, 12.5±1.3nm and 27.8±0.5mL/g respectively.
Xiaoqi Xu +4 more
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This study aimed at investigating the chain conformation and physicochemical properties of fucosylated chondroitin sulfate extracted from sea cucumber Apostichopus japonicas (Aj-fCS). By using HPSEC-MALLS-Visc-RI, Mw, z(1/2), Rh and [η] for Aj-fCS were determined as 58.0±4.4kDa, 21.8±1.3nm, 12.5±1.3nm and 27.8±0.5mL/g respectively.
Xiaoqi Xu +4 more
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Carbohydrate Polymers, 2013
A method for depolymerization of a novel fucosylated chondroitin sulfate from Pearsonothuria graeffei (fCS-Pg) using (60)Co irradiation in water solution was developed in the current study. Fragments with varying molecular weights were obtained by (60)Co irradiation at different dosages and sample concentrations.
Nian, Wu +8 more
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A method for depolymerization of a novel fucosylated chondroitin sulfate from Pearsonothuria graeffei (fCS-Pg) using (60)Co irradiation in water solution was developed in the current study. Fragments with varying molecular weights were obtained by (60)Co irradiation at different dosages and sample concentrations.
Nian, Wu +8 more
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Chemical Synthesis of Fucosylated Chondroitin Sulfate Oligosaccharides
The Journal of Organic Chemistry, 2020Fucosylated chondroitin sulfates (FuCSs) are a unique type of polysaccharides occurring in sea cucumber that show a variety of biological activities. In particular, well-defined FuCS oligosaccharides, consisting of a trisaccharide repeating unit of β-d-GalNAc(4,6-diS)-(1→4)-[α-l-Fuc(2,4-diS)-(1→3)]-β-d-GlcUA, display potent anticoagulant activity via ...
Liangzhong Zhang +3 more
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Chemical Fucosylation of a Polysaccharide: A Semisynthetic Access to Fucosylated Chondroitin Sulfate
Biomacromolecules, 2015Chemical O-glycosylation of polysaccharides is an almost unexplored reaction. This is mainly due to the difficulties in derivatizing such complex biomacromolecules in a quantitative manner and with a fine control of the obtained structural parameters.
LAEZZA, ANTONIO +6 more
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