Results 171 to 180 of about 13,321 (212)

Site-Specific Analysis of Core and Antenna Fucosylation on Serum Glycoproteins.

Analytical Chemistry
Fucosylation is an important structural feature of glycans and plays an essential role in the regulation of glycoprotein functions. Fucosylation can be classified into core- (CF) and antenna-fucosylation (AF, also known as (sialyl-) Lewis) based on the ...
Jun Li, Didi Liu, Yingjie Zhang, Jiechen Shen, Wei Dan, Zexuan Chen, Shisheng Sun   +6 more
semanticscholar   +1 more source

Hepatic GDP-fucose transporter SLC35C1 attenuates cholestatic liver injury and inflammation by inducing CEACAM1 N153 fucosylation

Hepatology
Background and Aims: Inflammatory response is crucial for bile acid (BA)-induced cholestatic liver injury, but molecular mechanisms remain to be elucidated.
Liangjun Zhang, Pingfan Xie, Mingqiao Li, Xiaoxun Zhang, Shuke Fei, N. Zhao, Ling Li, Qiaoling Xie, Ziqian Xu, Wan Tang, Guanyu Zhu, Zhixian Zhu, Zuzhi Xu, Jianwei Li, Chengcheng Zhang, James L. Boyer, Wen-sheng Chen, Shi-Ying Cai, Qiong-Jing Pan, Jin Chai   +19 more
semanticscholar   +1 more source

Stereoselective Organocatalytic Fucosylation with Isothioureas

Organic Letters
This letter describes a catalytic, α-selective glycosylation of fucosyl chloride donors mediated by a nucleophilic thiourea. This reaction is highly selective in forming both α-fucosyl and α-2-deoxy-2-azido-fucosylated glycosides, including sterically encumbered linkages. Both conformationally flexible and constrained donors participate, giving good to
Charles Enlow, Riley N. Brown, Trevor E. Hoodenpyle, Connor J. Smith, Bhaswati Ghosh, Abram J. Axelrod   +5 more
openaire   +2 more sources

Dissociation Profile of Protonated Fucosyl Glycopeptides and Quantitation of Fucosylation Levels of Glycoproteins by Mass Spectrometry

Journal of Proteome Research, 2008
Mass spectrometry of glycopeptides is an efficient strategy for profiling glycans at specific sites in glycoproteins. To assess the reliability of this method for determining the fucosylation levels of glycoproteins, we conducted mass spectrometry of fucosylated glycopeptides from transferrin and haptoglobin.
Michiko, Tajiri, Machiko, Kadoya, Yoshinao, Wada   +2 more
openaire   +2 more sources

Biological Function of Fucosylation in Cancer Biology

Journal of Biochemistry, 2007
Fucosylation is one of the most common modifications involving oligosaccharides on glycoproteins or glycolipids. Fucosylation comprises the attachment of a fucose residue to N-glycans, O-glycans and glycolipids. O-Fucosylation, which is a special type of fucosylation, is very important for Notch signalling.
Eiji, Miyoshi, Kenta, Moriwaki, Tsutomu, Nakagawa   +2 more
openaire   +2 more sources

Fucosylation and Cancer

2009
Fucosylation is one of the most common modifications involving oligosaccharides on glycoproteins or glycolipids. Fucosylation comprises the attachment of a fucose residue to N-glycans, O-glycans, and glycolipids. O-Fucosylation, a special type of fucosylation, is very important for Notch signaling.
openaire   +1 more source

CEBPB regulates the migration, invasion and EMT of breast cancer cells by inhibiting THBS2 expression and O-fucosylation.

Human Molecular Genetics, 2023
Liqiang Qi, Bo Sun, Beibei Yang, Su Lu
semanticscholar   +1 more source

Fucosylated Glycans in Innate and Adaptive Immmunity

2005
Mammalian glycans are characterized by fucose modifications. Some of these are constitutively expressed, whereas others are under temporal, developmental, and lineage-specific control. These modifications include fucose in alpha1,3-linkage to aspragine-linked, lipid-linked and serine/threonine-linked glycans.
openaire   +2 more sources

Fucosylation

Journal of the American College of Cardiology
Harrison W. Farber, Noah C. Schoenberg
openaire   +1 more source

Congenital disorders of glycosylation with defective fucosylation

Journal of Inherited Metabolic Disease, 2021
Tooba Momen, Christian Thiel, Johannes Mayr   +2 more
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