Results 111 to 120 of about 74,907,945 (195)

FUT6 Suppresses the Proliferation, Migration, Invasion, and Epithelial–Mesenchymal Transition of Esophageal Carcinoma Cells via the Epidermal Growth Factor Receptor/Extracellular Signal-Regulated Kinase Signaling Pathway

The Turkish Journal of Gastroenterology
Background/Aims: Esophageal cancer (ESCA) is a high-incidence disease worldwide, of which the 5-year survival rate remains dismal since the cellular basis of ESCA remains largely unclear.
Jianle Lao, Yanmin Pang, Hongming Chen, Xiqiang Tang, Rizhu Li, Danlei Tong, Ping Qiu, Qianli Tang   +7 more
doaj   +1 more source

The α(1,3)Fucosyltransferase Fuc-TVII Controls Leukocyte Trafficking through an Essential Role in L-, E-, and P-selectin Ligand Biosynthesis

, 1996
α(1,3)Fucosylated oligosaccharides represent components of leukocyte counterreceptors for E- and P-selectins and of L-selectin ligands expressed by lymph node high endothelial venules (HEV).
Kelly, Robert J, Hindsgaul, Ole, Malý, Petr, Petryniak, Bronislawa, Lowe, John B, Smith, Peter L, Gersten, Kevin M, Cheng, Guiying, Isogai, Yukihiro, Marks, Rory M, Camper, Sally A, Camphausen, Ray T, von Andrian, Ulrich H, Rogers, Clare E, Thall, Aron D, Saunders, Thomas L, Sullivan, Francis X   +16 more
core   +1 more source

Molecular Characterization of Secretor Typeα(1, 2)-fucosyltransferase Gene Deficiency in the Philippine Population

, 2012
[[abstract]] We analyzed the seven mutations which are responsible for the deficiency of the secretor type α(1,2)-fucosyltransferase gene product, Se enzyme, in the Philippine population. One hundred and one unrelated Filipinos in Taiwan were studied.
Peng, C. T. ; Tsai, C. H. ; Lin, T. P. ; Perng, L. I. ; Kao, M. C. ; Yang, T. Y. ; Wang, Nancy M. ; Liu, T. C. ; Lin, S. F. ; Chang, J. G.
core  

α1,4-Fucosyltransferase Activity: A Significant Function in the Primate Lineage has Appeared Twice Independently

, 2002
International audienceIn the animal kingdom the enzymes that catalyze the formation of alpha1,4 fucosylated-glycoconjugates are known only in apes (chimpanzee) and humans.
Germot, Agnès, Dupuy, Fabrice, Marenda, Mickaël, Blancher, Antoine, Oriol, Rafaël, Julien, Raymond, Maftah, Abderrahman   +6 more
core   +1 more source

Fucosyltransferase 8 modulates receptor tyrosine kinase activation and temozolomide resistance in glioblastoma cells.

American journal of cancer research
Alteration of extracellular glycosylation is a hallmark of malignant characteristics. In this study, we revealed that fucosyltransferase 8 (FUT8), an enzyme that mediates the core fucosylation of N-linked glycosylation, is an important regulator of malignant characteristics in human glioma that acts by modifying the activities of both the HGF receptor (
Kuo-Chen, Wei, You-Cheng, Lin, Chia-Hua, Chen, Yin-Hung, Chu, Chiung-Yin, Huang, Wen-Chieh, Liao, Chiung-Hui, Liu   +6 more
openaire   +1 more source

Trafficking and localization studies of recombinant α1,3-fucosyltransferase VI stably expressed in CHO cells [PDF]

, 2017
Peripheral α1,3-fucosylation of glycans occurs by the action of either one of five different α1,3-fucosyltransferases (Fuc-Ts) cloned to date. Fuc-TVI is one of the α1,3-fucosyltransferases which is capable to synthesize selectin ligands.
Berger, Eric G., Katopodis, Andreas G., Bowen, Benjamin R., Borsig, Lubor   +3 more
core  

Fucosyltransferase 8 (FUT8) and core fucose expression in oxidative stress response

Fucosyltransferase 8 (FUT8) and core fucose expression in oxidative stress response
GlycoMaple is a new tool to predict glycan structures based on the expression levels of 950 genes encoding glycan biosynthesis-related enzymes and proteins using RNA-seq data. The antioxidant response, protecting cells from oxidative stress, has been focused on because its activation may relieve pathological conditions, such as neurodegenerative ...
openaire   +1 more source

Fucosyltransferase 8 as a driver of melanoma metastasis: a new target for melanoma therapy?

Translational Cancer Research, 2017
Chi-Huey Wong, Tsui-Ling Hsu
openaire   +1 more source

Fig. S1 from Fucosyltransferase 8 facilitates EMT in glioblastoma cells through the remodeling of TGF-β receptor core fucosylation

The correlation analysis of other transcription factors with FUT8. Scatter plots showing the correlations between C1GALT1 expression and that of the top eight transcription factors excluding E2F4, namely E2F, E2F-1, E2F-2, E2F-3a, E2F-5, Egr-2, and POU3F1, in the patients including lower grade glioma (LGG) and GBM from the TCGA database (Pearson’s ...
Xu, Bo, Zhang, Zhengrong, Yu, You, Ao, Xin, Zhang, Mingzhu, Yang, Mengjiao, Zhang, Zhenwang, Wei, Mingjie, Shan, Shigang, Zhu, He, Su, Yanting   +10 more
openaire   +1 more source