Results 91 to 100 of about 74,907,945 (195)

Golgi fucosyltransferase 1 reveals its important role in α-1,4-fucose modification of N-glycan in CRISPR Phaeodactylum tricornutum

, 2023
Phaeodactylum tricornutum (Pt) is a critical microbial cell factory to produce a wide spectrum of marketable products including recombinant biopharmaceutical N-glycoproteins.
Weizhou Chen, Jianchao Yang, Xihui Xie, Hua Du, Jichen Chen, Xiaojuan Liu, Hong Du, Yangmin Gong, Zhengyi Liu, Edmond Sanganyado   +9 more
core   +1 more source

Non-Secretor Status Due to FUT2 Stop Mutation Is Associated with Reduced Rotavirus Infections but Not with Other Enteric Pathogens in Rwandan Children

Microorganisms
Enteric pathogens remain a health threat for children in low-income countries. A single nucleotide polymorphism (SNP) in the FUT2 gene that precludes the expression of fucosyltransferase 2 has been reported to influence the susceptibility to rotavirus ...
Jean Bosco Munyemana, Jean Claude Kabayiza, Eric Seruyange, Staffan Nilsson, Gustaf E. Rydell, Anna Martner, Maria E. Andersson, Magnus Lindh   +7 more
doaj   +1 more source

Reinigung, Charakterisierung und Klonierung einer alpha1.6- Fucosyltransferase aus Gastropoden

, 2014
Es wäre hilfreich einen tieferen Einblick in die Gastropoden Glykobiologie zu gewinnen,da Strukturen und Mechanismen die nicht in höheren Tieren vorhanden sind als Werkzeug für die Schädlingsbekämpfung gezielt eingesetzt werden könnten.Der Schwerpunkt ...
Lucini, Chantal
core   +2 more sources

Fucosyltransferase 8 facilitates EMT in glioblastoma cells through the remodelling of TGF-β receptor core fucosylation

Open Biology
Abstract Fucosyltransferase 8 (FUT8), a glycosyltransferase responsible for core fucosylation, is overexpressed in numerous cancers and promotes many malignant processes such as cell proliferation, invasion and migration. Transforming growth factor-β (TGF-β) stimulation promotes epithelial–mesenchymal transition (EMT), a pivotal ...
Bo Xu, Zhengrong Zhang, You Yu, Xin Ao, Mingzhu Zhang, Mengjiao Yang, Zhenwang Zhang, Mingjie Wei, Shigang Shan, He Zhu, Yanting Su   +10 more
openaire   +2 more sources

FUT3–B3GNT3 interaction promotes pancreatic cancer progression and chemoresistance via NF-κB signaling mediated autophagy

European Journal of Medical Research
Pancreatic ductal adenocarcinoma (PDAC) is prone to drug resistance and a role for fucosyltransferase 3 (FUT3) is increasingly recognized. The current study investigated the mechanisms by which FUT3 contributes to PDAC.
Lei Jin, Wenjie Han, Junwei Zou, Xiaolei Tang, Peng Chen, Hao Xie, Bing Zhou, Daohai Qian, Yue Yu   +8 more
doaj   +1 more source

Mechanism of human alpha-1,3-fucosyltransferase V : glycosidic cleavage occurs prior to nucleophilic attack

, 1997
α-1,3-Fucosyltransferase V (FucT V) catalyzes the transfer of l-fucose from the donor sugar guanosine 5'-diphospho-β-l-fucose (GDP-Fuc) to an acceptor sugar.
Hung, Shang-Cheng, Burkart, Michael D., Wittmann, Valentin, Wong, Chi-Huey, Murray, Brion W., Michael D. Burkart, Brion W. Murray, Shang-Cheng Hung, Chi-Huey Wong, Valentin Wittmann   +9 more
core   +1 more source

Core Fucosylation Represses SMURF1‐Dependent Degradation of CD47 to Promote Tumor Immune Evasion

Advanced Science
Glycosylation, the covalent attachment of glycans to proteins, lipids, and RNAs, is fundamental in regulating diverse biological processes. Glycosylation patterns are aberrantly altered in the tumor microenvironment and closely associated with tumor ...
Yuting Cao, Siyuan Chai, Mingyang Li, Xiaoming Chen, Jiating Hu, Bingyi Lin, Liming Wu, Wen Yi, Qiang Zhu   +8 more
doaj   +1 more source

Comparative whole genome re-sequencing analysis in upland New Rice for Africa: insights into the breeding history and respective genome compositions

Rice, 2018
Background Increasing rice demand is one of the consequences of the steadily improving socio-economic status of the African countries. New Rice for Africa (NERICA), which are interspecific hybrids between Asian and African rice varieties, are one of ...
Naoki Yamamoto, Richard Garcia, Tomohiro Suzuki, Celymar Angela Solis, Yuichi Tada, Ramaiah Venuprasad, Ajay Kohli   +6 more
doaj   +1 more source

Molecular Analysis of Secretor Type α(1,2)-fucosyltransferase Gene Mutations in the Chinese and Thai Populations

, 2012
[[abstract]]Keywords:FUT2 = α(1, 2)-fucosyltransferase (Se) gene;FUT3 = α(1,3/1,4)-fucosyltransferase (Le) gene;nt = nucleotide;PCR = polymerase chain reaction;RBC(s) = red cell(s) BACKGROUND: The human Lewis histo-blood group system belongs to a family ...
Chang, J. G. ; Yang, T. Y. ; Liu, T. C. ; Lin, T. P. ; Hu, C. J. ; Kao, M. C. ; Wang, Nancy M. ; Tsai, F. J. ; Peng, C. T. ; Tsai, C. H.
core  

Synthetic Potential of Fucosyltransferase III for the Synthesis of Fluorescent-Label Milk Oligosaccharides

, 2005
Various fundamental biologic roles of milk oligosaccharides have been recognized; however, their structure-affinity relationship is still not fully revealed.
Beatrice Wagner, S. Rabbani, F. Compostella, B. Ernst, Laura Franchini, Luigi Panza, Beat Ernst, Federica Compostella, B. Wagner, L. Franchini, L. Panza, Said Rabbani, Franchini, Laura, Rabbani, Said, Compostella, Federica, Panza, Luigi, Wagner, Beatrice, Ernst, Beat   +17 more
core   +1 more source