The "Sweet" crosstalk between refractory leukemia cells and vascular niche. [PDF]
Cheng H.
europepmc +1 more source
Divergent Enzymatic Synthesis of a Comprehensive Type‑1 Glycan Determinant Library. [PDF]
Bai G +6 more
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Escherichia coli expressing the kpsM gene exacerbates drug-induced liver injury through up-regulating α1,2-fucosyltransferase and disturbing the host taurine metabolism-from animal models and clinical studies. [PDF]
Gao W +15 more
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Rotavirus Infection as a Contributor to Early-Onset Type 1 Diabetes: Review and Recommendations. [PDF]
Rogers MAM, Rogers SO.
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The Interplay Between CA19-9 and the Lewis Blood Group System: Implications for the Diagnosis of Gallbladder Cancer. [PDF]
Liu Y +6 more
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Genomic structure and promoter analysis of the human α 1,6-fucosyltransferase gene (FUT 8)
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Recently, studies have shown that Fucosylation plays an important role in the invasion and metastatic process of CSLCs. Understanding the expression pattern of fucosyltransferase (FUT) genes may help to suggest better-targeted therapy strategies for esophageal squamous cell carcinoma (ESCC). The study aimed to address the expression pattern of FUT gene
Zahra Sadeghzadeh +3 more
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Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer. It is an aggressive malignancy associated with poor prognosis because of recurrence, metastasis, and treatment resistance. Aberrant glycosylation of cancer cells triggers their migration and invasion and is considered one of the most important prognostic cancer ...
Kazuhiro, Tada +13 more
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Substrate Preference and Interplay of Fucosyltransferase 8 and N-Acetylglucosaminyltransferases
Journal of the American Chemical Society, 2017The core fucosylation of N-glycans on glycoproteins is catalyzed by fucosyltransferase 8 (FUT8) in mammalian cells and is involved in various biological functions, such as protein function, cancer progression, and postnatal development. The substrate specificity of FUT8 toward bi-antennary N-glycans has been reported, but it is unclear with regard to ...
Tzu-Hao Tseng +6 more
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A rare form of congenital disorder of glycosylation (CDG) was recently discovered in individuals with biallelic mutations in fucosyltransferase 8 (FUT8). The clinical characteristics of patients with FUT8-CDG include intrauterine growth retardation, feeding difficulties, hypotonia, microcephaly, seizures, short stature, developmental delay, and ...
Anna, Schweigert, Raymond G, Areaux
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