Results 1 to 10 of about 6,409 (197)

AtFUT4 and AtFUT6 Are Arabinofuranose-Specific Fucosyltransferases

Frontiers in Plant Science, 2021
The bulk of plant biomass is comprised of plant cell walls, which are complex polymeric networks, composed of diverse polysaccharides, proteins, polyphenolics, and hydroxyproline-rich glycoproteins (HRGPs).
Maria J. Soto, Maria J. Soto, Maria J. Soto, Pradeep Kumar Prabhakar, Pradeep Kumar Prabhakar, Pradeep Kumar Prabhakar, Hsin-Tzu Wang, Hsin-Tzu Wang, Hsin-Tzu Wang, Jason Backe, Jason Backe, Digantkumar Chapla, Digantkumar Chapla, Max Bartetzko, Ian M. Black, Parastoo Azadi, Parastoo Azadi, Maria J. Peña, Maria J. Peña, Fabian Pfrengle, Fabian Pfrengle, Kelley W. Moremen, Kelley W. Moremen, Breeanna R. Urbanowicz, Breeanna R. Urbanowicz, Breeanna R. Urbanowicz, Michael G. Hahn, Michael G. Hahn, Michael G. Hahn   +28 more
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Fucosyltransferases Regulated by Fusobacterium Nucleatum and Act as Novel Biomarkers in Colon Adenocarcinoma

Journal of Inflammation Research, 2023
Pengfei Wang,1,2,* Xuxu Liu,1,2,* Jingjing Yu,1,2 Ziang Meng,1,2 Zhenyi Lv,1,2 Ce Shang,1,2 Qi Geng,1,2 Dawei Wang,1,2 Dongbo Xue,1,2 Long Li3 1Department of General Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin ...
Wang P, Liu X, Yu J, Meng Z, Lv Z, Shang C, Geng Q, Wang D, Xue D, Li L   +9 more
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Structural Insights in Mammalian Sialyltransferases and Fucosyltransferases: We Have Come a Long Way, but It Is Still a Long Way Down

Molecules, 2021
Mammalian cell surfaces are modified with complex arrays of glycans that play major roles in health and disease. Abnormal glycosylation is a hallmark of cancer; terminal sialic acid and fucose in particular have high levels in tumor cells, with positive ...
Ravneet Kaur Grewal, Abdul Rajjak Shaikh, Suresh Gorle, Manjeet Kaur, Paula Alexendra Videira, Luigi Cavallo, Mohit Chawla   +6 more
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The contribution of fucosyltransferases to cancer biology [PDF]

Brazilian Journal of Biology
Fucosyltransferases are enzymes that transfer L-fucose residues from a donor substrate to target molecules. These enzymes are encoded by genes known as FUTs (FUT1 to FUT-11), along with POFUT1 and 2.
A. O. Vasconcelos, L. M. Vieira, C. R. C. Rocha, E. I. C. Beltrão   +3 more
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FUT10 and FUT11 are protein O-fucosyltransferases that modify protein EMI domains. [PDF]

Nat Chem Biol
O-Fucosylation plays crucial roles in various essential biological events. Alongside the well-established O-fucosylation of epidermal growth factor-like repeats by protein O-fucosyltransferase 1 (POFUT1) and thrombospondin type 1 repeats by POFUT2, we ...
Hao H, Yuan Y, Ito A, Eberand BM, Tjondro H, Cielesh M, Norris N, Moreno CL, Maxwell JWC, Neely GG, Payne RJ, Kebede MA, Urbauer RJB, Passam FH, Larance M, Haltiwanger RS.   +15 more
europepmc   +2 more sources

Fucosylation in digestive inflammatory diseases and cancers: From mechanical studies to clinical translation [PDF]

Genes and Diseases
Fucosylation is a post-translational modification that attaches fucose to glycoproteins or glycolipids, thereby influencing their biological functions. Consequently, fucosylation proves indispensable for many biological processes, such as ligand–receptor
Caihan Duan, Junhao Wu, Zhe Wang, Xiaohua Hou, Chaoqun Han   +4 more
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The ABC type fucose operon regulated by XtrSs through CcpA contributes to Streptococcus suis survival in macrophages [PDF]

Virulence
Streptococcus suis (S. suis), an important zoonotic pathogen, poses a huge threat to the pig industry and human health. The fucose operon (FCS) is found in many bacteria that utilize host glycosylation modifications, contributing to bacterial growth and ...
Song Liang, Yumin Zhang, Shidan Zhang, Qiankun Bai, Xinming Pan, Jianan Liu, Qibing Gu, Huochun Yao, Guangjin Liu   +8 more
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Characterisation of FUT4 and FUT6 α-(1 → 2)-fucosyltransferases reveals that absence of root arabinogalactan fucosylation increases Arabidopsis root growth salt sensitivity. [PDF]

PLoS ONE, 2014
Plant type II arabinogalactan (AG) polysaccharides are attached to arabinogalactan proteins (AGPs) at hydroxyproline residues, and they are very diverse and heterogeneous structures.
Theodora Tryfona, Tina E Theys, Tanya Wagner, Katherine Stott, Kenneth Keegstra, Paul Dupree   +5 more
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Structure, function, and implications of fucosyltransferases in health and disease [PDF]

Nature Communications
Fucosylation is a ubiquitous glycosylation event that shapes cellular communication and immunity. Catalyzed by fucosyltransferases (FUTs), this reaction encompasses diverse substrates, mechanisms, and biologic consequences. In this Review, we explore the
Mattia Ghirardello, Inmaculada Yruela, Pedro Merino, Robert Sackstein, Ignacio Sanz-Martínez, Ramón Hurtado-Guerrero   +5 more
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Fucose as a nutrient ligand for Dikarya and a building block of early diverging lineages [PDF]

IMA Fungus, 2023
Fucose is a deoxyhexose sugar present and studied in mammals. The process of fucosylation has been the primary focus in studies relating to fucose in animals due to the presence of fucose in Lewis antigens.
Małgorzata Orłowska, Drishtee Barua, Sebastian Piłsyk, Anna Muszewska   +3 more
doaj   +2 more sources