Results 11 to 20 of about 5,422 (250)

AtFUT4 and AtFUT6 Are Arabinofuranose-Specific Fucosyltransferases [PDF]

Frontiers in Plant Science, 2021
The bulk of plant biomass is comprised of plant cell walls, which are complex polymeric networks, composed of diverse polysaccharides, proteins, polyphenolics, and hydroxyproline-rich glycoproteins (HRGPs).
Maria J. Soto, Maria J. Soto, Maria J. Soto, Pradeep Kumar Prabhakar, Pradeep Kumar Prabhakar, Pradeep Kumar Prabhakar, Hsin-Tzu Wang, Hsin-Tzu Wang, Hsin-Tzu Wang, Jason Backe, Jason Backe, Digantkumar Chapla, Digantkumar Chapla, Max Bartetzko, Ian M. Black, Parastoo Azadi, Parastoo Azadi, Maria J. Peña, Maria J. Peña, Fabian Pfrengle, Fabian Pfrengle, Kelley W. Moremen, Kelley W. Moremen, Breeanna R. Urbanowicz, Breeanna R. Urbanowicz, Breeanna R. Urbanowicz, Michael G. Hahn, Michael G. Hahn, Michael G. Hahn   +28 more
doaj   +7 more sources

The contribution of fucosyltransferases to cancer biology [PDF]

Brazilian Journal of Biology
Fucosyltransferases are enzymes that transfer L-fucose residues from a donor substrate to target molecules. These enzymes are encoded by genes known as FUTs (FUT1 to FUT-11), along with POFUT1 and 2.
A. O. Vasconcelos, L. M. Vieira, C. R. C. Rocha, E. I. C. Beltrão   +3 more
doaj   +3 more sources

Intestinal Fut2 deficiency exacerbated alcohol-related liver disease by disrupting nicotinamide metabolism. [PDF]

Clin Transl Med
Loss of intestinal epithelial fucosylation exacerbates alcohol‐related liver injuries. Intestinal epithelial deletion of Fut2 disrupts nicotinamide (NAM) metabolism due to the decline in bacterial nicotinamidase (PncA). Supplemented with pncA overexpressed E.coli to restore gut PncA levels can improve liver damage in alcohol‐induced intestinal ...
Chen L, Yin Z, Shang L, Yuan H, Gao W, Wang S, Wang S, Hou X, Yang S, Chu H.   +9 more
europepmc   +2 more sources

FUT8 (fucosyltransferase 8 (alpha (1,6) fucosyltransferase)) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on FUT8 (fucosyltransferase 8 (alpha (1,6) fucosyltransferase)), with data on DNA, on the protein encoded, and where the gene is implicated.
Ihara, H, Gao, CX, Ikeda, Y, Taniguchi, N   +3 more
openaire   +3 more sources

Fucosylation with fucosyltransferase VI or fucosyltransferase VII improves cord blood engraftment [PDF]

Cytotherapy, 2014
Background aims: Advantages associated with the use of cord blood (CB) transplantation include the availability of cryopreserved units, ethnic diversity and lower incidence of graft-versus-host disease compared with bone marrow or mobilized peripheral blood. However, poor engraftment remains a major obstacle.
Junjun Lu, Katayoun Rezvani, Hong Yang, Gianpietro Dotti, Laurence J.N. Cooper, Nina Shah, Ian K. McNiece, Xiaoying Liu, Indreshpaul Kaur, Leonard P. Miller, Barbara Savoldo, Michael W. Thomas, Simrit Parmar, Richard E. Champlin, Simon N. Robinson, Catherine M. Bollard, Patrick A. Zweidler-McKay, Amer Najjar, Paul J. Simmons, Beatriz Martín-Antonio, Elizabeth J. Shpall   +20 more
openaire   +3 more sources

Subcellular localisation of cerebral fucosyltransferase [PDF]

FEBS Letters, 1984
GDP‐fucose : asialofetuin fucosyltransferase from sheep brain was fractionated on a sucrose gradient into two activity peaks. Using purification on Ficoll adapted from the proposed method [(1980) J. Neurochem. 35, 281‐296], double localisation of cerebral fucosyltransferase was confirmed and the subcellular active fractions identified as light ...
Broquet, P., Serres-Guillaumond, M., Baubichon-Cortay, H., Peschard, Mj, Louisot, P.   +4 more
openaire   +3 more sources

FUT8 Alpha-(1,6)-Fucosyltransferase in Cancer [PDF]

International Journal of Molecular Sciences, 2021
Aberrant glycosylation is a universal feature of cancer cells that can impact all steps in tumour progression from malignant transformation to metastasis and immune evasion. One key change in tumour glycosylation is altered core fucosylation. Core fucosylation is driven by fucosyltransferase 8 (FUT8), which catalyses the addition of α1,6-fucose to the ...
Kayla Bastian, Emma Scott, David J. Elliott, Jennifer Munkley   +3 more
openaire   +4 more sources

A new superfamily of protein-O-fucosyltransferases,  2-fucosyltransferases, and  6-fucosyltransferases: phylogeny and identification of conserved peptide motifs [PDF]

Glycobiology, 2003
The presence of three conserved peptide motifs shared by alpha2-fucosyltransferases, alpha6-fucosyltransferases, the protein-O-fucosyltransferase family 1 (POFUT1) and a newly identified protein-O-fucosyltransferase family 2 (POFUT2), together with evidence that the present genes encoding for these enzymes have originated from a common ancestor by ...
Martinez-Duncker, I., Mollicone, R., Candelier, J.J., Breton, C., Oriol, R.   +4 more
openaire   +3 more sources

Fucosyltransferases in Schistosoma mansoni development [PDF]

Glycobiology, 2001
Glycoconjugate-bound fucose, abundant in the parasite Schistosoma mansoni, has been found in the form of Fucalpha1,3GlcNAc, Fucalpha1,2Fuc, Fucalpha1,6GlcNAc, and perhaps Fucalpha1,4GlcNAc linkages. Here we quantify fucosyltransferase activities in three developmental stages of S. mansoni.
Mette Strand, Yoshitaka Ichikawa, J. T. August, Ronald L. Schnaar, Ernesto T. A. Marques, Gerald W. Hart   +5 more
openaire   +3 more sources

An essential, kinetoplastid-specific GDP-Fuc: β-D-Gal α-1,2-fucosyltransferase is located in the mitochondrion of Trypanosoma brucei

eLife, 2021
Fucose is a common component of eukaryotic cell-surface glycoconjugates, generally added by Golgi-resident fucosyltransferases. Whereas fucosylated glycoconjugates are rare in kinetoplastids, the biosynthesis of the nucleotide sugar GDP-Fuc has been ...
Giulia Bandini, Sebastian Damerow, Maria Lucia Sempaio Guther, Hongjie Guo, Angela Mehlert, Jose Carlos Paredes Franco, Stephen Beverley, Michael AJ Ferguson   +7 more
doaj   +1 more source