Results 11 to 20 of about 5,550 (234)

Host Cell Response to Rotavirus Infection with Emphasis on Virus–Glycan Interactions, Cholesterol Metabolism, and Innate Immunity

Viruses, 2023
Although rotavirus A (RVA) is the primary cause of acute viral gastroenteritis in children and young animals, mechanisms of its replication and pathogenesis remain poorly understood.
Molly Raque, Sergei A. Raev, Yusheng Guo, Maryssa K. Kick, Linda J. Saif, Anastasia N. Vlasova   +5 more
doaj   +1 more source

AtFUT4 and AtFUT6 Are Arabinofuranose-Specific Fucosyltransferases

Frontiers in Plant Science, 2021
The bulk of plant biomass is comprised of plant cell walls, which are complex polymeric networks, composed of diverse polysaccharides, proteins, polyphenolics, and hydroxyproline-rich glycoproteins (HRGPs).
Maria J. Soto, Maria J. Soto, Maria J. Soto, Pradeep Kumar Prabhakar, Pradeep Kumar Prabhakar, Pradeep Kumar Prabhakar, Hsin-Tzu Wang, Hsin-Tzu Wang, Hsin-Tzu Wang, Jason Backe, Jason Backe, Digantkumar Chapla, Digantkumar Chapla, Max Bartetzko, Ian M. Black, Parastoo Azadi, Parastoo Azadi, Maria J. Peña, Maria J. Peña, Fabian Pfrengle, Fabian Pfrengle, Kelley W. Moremen, Kelley W. Moremen, Breeanna R. Urbanowicz, Breeanna R. Urbanowicz, Breeanna R. Urbanowicz, Michael G. Hahn, Michael G. Hahn, Michael G. Hahn   +28 more
doaj   +1 more source

Acute and chronic lung inflammation drives changes in epithelial glycans

Frontiers in Immunology, 2023
IntroductionAsthma is the most common chronic inflammatory disease and it is characterized by leukocyte infiltration and tissue remodeling, with the latter generally referring to collagen deposition and epithelial hyperplasia.
Carlos A. Alvarez, Emily Qian, Emily Qian, Leandre M. Glendenning, Kalob M. Reynero, Emily N. Kukan, Brian A. Cobb   +6 more
doaj   +1 more source

FUT8 (fucosyltransferase 8 (alpha (1,6) fucosyltransferase)) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on FUT8 (fucosyltransferase 8 (alpha (1,6) fucosyltransferase)), with data on DNA, on the protein encoded, and where the gene is implicated.
Ihara, H, Gao, CX, Ikeda, Y, Taniguchi, N   +3 more
openaire   +2 more sources

Fucosyltransferases: structure/function studies [PDF]

Glycobiology, 2001
Alpha3-fucosyltransferases (alpha3-FucTs) catalyze the final step in the synthesis of a range of important glycoconjugates that function in cell adhesion and lymphocyte recirculation. Six members of this family of enzymes have been cloned from the human genome, and their expression pattern has been shown to be highly regulated. Each enzyme has a unique
T, de Vries, R M, Knegtel, E H, Holmes, B A, Macher   +3 more
openaire   +2 more sources

Fucosylation with fucosyltransferase VI or fucosyltransferase VII improves cord blood engraftment [PDF]

Cytotherapy, 2014
Background aims: Advantages associated with the use of cord blood (CB) transplantation include the availability of cryopreserved units, ethnic diversity and lower incidence of graft-versus-host disease compared with bone marrow or mobilized peripheral blood. However, poor engraftment remains a major obstacle.
Simon N, Robinson, Michael W, Thomas, Paul J, Simmons, Junjun, Lu, Hong, Yang, Simrit, Parmar, Xiaoying, Liu, Nina, Shah, Beatriz, Martín-Antonio, Catherine, Bollard, Gianpietro, Dotti, Barbara, Savoldo, Laurence J, Cooper, Amer, Najjar, Katayoun, Rezvani, Indreshpaul, Kaur, Ian K, McNiece, Richard E, Champlin, Leonard P, Miller, Patrick A, Zweidler-McKay, Elizabeth J, Shpall   +20 more
openaire   +2 more sources

FUT3 facilitates glucose metabolism of lung adenocarcinoma via activation of NF-κB pathway

BMC Pulmonary Medicine, 2023
Objective Fucosyltransferases (FUTs) molecules have been identified to be involved in carcinogenesis of malignant tumors. Nevertheless, the biological function of fucosyltransferases-3 (FUT3) in lung adenocarcinoma (LUAD) malignant phenotype remains ...
Lanlan Lin, Xiaohui Chen, Guofu Lin, Luyang Chen, Yuan Xu, Yiming Zeng   +5 more
doaj   +1 more source

An essential, kinetoplastid-specific GDP-Fuc: β-D-Gal α-1,2-fucosyltransferase is located in the mitochondrion of Trypanosoma brucei

eLife, 2021
Fucose is a common component of eukaryotic cell-surface glycoconjugates, generally added by Golgi-resident fucosyltransferases. Whereas fucosylated glycoconjugates are rare in kinetoplastids, the biosynthesis of the nucleotide sugar GDP-Fuc has been ...
Giulia Bandini, Sebastian Damerow, Maria Lucia Sempaio Guther, Hongjie Guo, Angela Mehlert, Jose Carlos Paredes Franco, Stephen Beverley, Michael AJ Ferguson   +7 more
doaj   +1 more source

Publisher Correction: Functional characterization of Schistosoma mansoni fucosyltransferases in Nicotiana benthamiana plants

Scientific Reports, 2021
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Kim van Noort, Dieu‑Linh Nguyen, Verena Kriechbaumer, Chris Hawes, Cornelis H. Hokke, Arjen Schots, Ruud H. P. Wilbers   +6 more
doaj   +1 more source

Structural Insights in Mammalian Sialyltransferases and Fucosyltransferases: We Have Come a Long Way, but It Is Still a Long Way Down

Molecules, 2021
Mammalian cell surfaces are modified with complex arrays of glycans that play major roles in health and disease. Abnormal glycosylation is a hallmark of cancer; terminal sialic acid and fucose in particular have high levels in tumor cells, with positive ...
Ravneet Kaur Grewal, Abdul Rajjak Shaikh, Suresh Gorle, Manjeet Kaur, Paula Alexendra Videira, Luigi Cavallo, Mohit Chawla   +6 more
doaj   +1 more source