Results 21 to 30 of about 5,550 (234)

Lipopolysaccharide diversity evolving in Helicobacter pylori communities through genetic modifications in fucosyltransferases. [PDF]

open access: yesPLoS ONE, 2008
Helicobacter pylori persistently colonizes the gastric mucosa of half the human population. It is one of the most genetically diverse bacterial organisms and subvariants are continuously emerging within an H. pylori population.
Christina Nilsson   +5 more
doaj   +1 more source

Fucosylated Antigens in Cancer: An Alliance toward Tumor Progression, Metastasis, and Resistance to Chemotherapy

open access: yesFrontiers in Oncology, 2018
Aberrant glycosylation of tumor cells is recognized as a universal hallmark of cancer pathogenesis. Overexpression of fucosylated epitopes, such as type I (H1, Lewisa, Lewisb, and sialyl Lewisa) and type II (H2, Lewisx, Lewisy, and sialyl Lewisx) Lewis ...
Athanasios Blanas   +4 more
doaj   +1 more source

Pathogenic Variants in Fucokinase Cause a Congenital Disorder of Glycosylation [PDF]

open access: yes, 2018
FUK encodes fucokinase, the only enzyme capable of converting L-fucose to fucose-1-phosphate, which will ultimately be used for synthesizing GDP-fucose, the donor substrate for all fucosyltransferases.
Bearden, David R.   +9 more
core   +1 more source

Human T cell glycosylation and implications on immune therapy for cancer [PDF]

open access: yes, 2020
Glycosylation is an important post-translational modification, giving rise to a diverse and abundant repertoire of glycans on the cell surface, collectively known as the glycome.
Callewaert, Nico   +3 more
core   +1 more source

.ALPHA.1,3-Fucosyltransferases.

open access: bronzeTrends in Glycoscience and Glycotechnology, 1996
Erika Staudacher
openalex   +3 more sources

Fucosyltransferase 1 and 2 play pivotal roles in breast cancer cells. [PDF]

open access: yes, 2019
FUT1 and FUT2 encode alpha 1, 2-fucosyltransferases which catalyze the addition of alpha 1, 2-linked fucose to glycans. Glycan products of FUT1 and FUT2, such as Globo H and Lewis Y, are highly expressed on malignant tissues, including breast cancer ...
Chang, Nai-Chuan   +9 more
core   +2 more sources

Fucosyltransferases Regulated by Fusobacterium Nucleatum and Act as Novel Biomarkers in Colon Adenocarcinoma

open access: yesJournal of Inflammation Research, 2023
Pengfei Wang,1,2,* Xuxu Liu,1,2,* Jingjing Yu,1,2 Ziang Meng,1,2 Zhenyi Lv,1,2 Ce Shang,1,2 Qi Geng,1,2 Dawei Wang,1,2 Dongbo Xue,1,2 Long Li3 1Department of General Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin ...
Wang P   +9 more
doaj  

Post-Synthetic Defucosylation of AGP by Aspergillus nidulans α-1,2-Fucosidase Expressed in Arabidopsis Apoplast Induces Compensatory Upregulation of α-1,2-Fucosyltransferases. [PDF]

open access: yesPLoS ONE, 2016
Cell walls are essential components of plant cells which perform a variety of important functions for the different cell types, tissues and organs of a plant.
Gennady V Pogorelko   +4 more
doaj   +1 more source

Alpha-(1,6)-fucosyltransferase (FUT8) affects the survival strategy of osteosarcoma by remodeling TNF/NF-κB2 signaling

open access: yesCell Death and Disease, 2021
Glycosylation is an important modification of membrane proteins that results in functional changes in many cellular activities, from cell-cell recognition to regulatory signaling.
Shanyi Lin   +7 more
doaj   +1 more source

Human fucosyltransferase 6 enables prostate cancer metastasis to bone [PDF]

open access: yes, 2014
Background: The interaction between human prostate cancer (PCa) cells and bone marrow (BM) endothelium follows a rolling-and-adhesion cascade mediated by E-selectin ligand (ESL): E-selectin.
Barthel, S R   +6 more
core   +1 more source

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