Results 21 to 30 of about 5,550 (234)
Lipopolysaccharide diversity evolving in Helicobacter pylori communities through genetic modifications in fucosyltransferases. [PDF]
Helicobacter pylori persistently colonizes the gastric mucosa of half the human population. It is one of the most genetically diverse bacterial organisms and subvariants are continuously emerging within an H. pylori population.
Christina Nilsson +5 more
doaj +1 more source
Aberrant glycosylation of tumor cells is recognized as a universal hallmark of cancer pathogenesis. Overexpression of fucosylated epitopes, such as type I (H1, Lewisa, Lewisb, and sialyl Lewisa) and type II (H2, Lewisx, Lewisy, and sialyl Lewisx) Lewis ...
Athanasios Blanas +4 more
doaj +1 more source
Pathogenic Variants in Fucokinase Cause a Congenital Disorder of Glycosylation [PDF]
FUK encodes fucokinase, the only enzyme capable of converting L-fucose to fucose-1-phosphate, which will ultimately be used for synthesizing GDP-fucose, the donor substrate for all fucosyltransferases.
Bearden, David R. +9 more
core +1 more source
Human T cell glycosylation and implications on immune therapy for cancer [PDF]
Glycosylation is an important post-translational modification, giving rise to a diverse and abundant repertoire of glycans on the cell surface, collectively known as the glycome.
Callewaert, Nico +3 more
core +1 more source
.ALPHA.1,3-Fucosyltransferases.
Erika Staudacher
openalex +3 more sources
Fucosyltransferase 1 and 2 play pivotal roles in breast cancer cells. [PDF]
FUT1 and FUT2 encode alpha 1, 2-fucosyltransferases which catalyze the addition of alpha 1, 2-linked fucose to glycans. Glycan products of FUT1 and FUT2, such as Globo H and Lewis Y, are highly expressed on malignant tissues, including breast cancer ...
Chang, Nai-Chuan +9 more
core +2 more sources
Pengfei Wang,1,2,* Xuxu Liu,1,2,* Jingjing Yu,1,2 Ziang Meng,1,2 Zhenyi Lv,1,2 Ce Shang,1,2 Qi Geng,1,2 Dawei Wang,1,2 Dongbo Xue,1,2 Long Li3 1Department of General Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin ...
Wang P +9 more
doaj
Post-Synthetic Defucosylation of AGP by Aspergillus nidulans α-1,2-Fucosidase Expressed in Arabidopsis Apoplast Induces Compensatory Upregulation of α-1,2-Fucosyltransferases. [PDF]
Cell walls are essential components of plant cells which perform a variety of important functions for the different cell types, tissues and organs of a plant.
Gennady V Pogorelko +4 more
doaj +1 more source
Glycosylation is an important modification of membrane proteins that results in functional changes in many cellular activities, from cell-cell recognition to regulatory signaling.
Shanyi Lin +7 more
doaj +1 more source
Human fucosyltransferase 6 enables prostate cancer metastasis to bone [PDF]
Background: The interaction between human prostate cancer (PCa) cells and bone marrow (BM) endothelium follows a rolling-and-adhesion cascade mediated by E-selectin ligand (ESL): E-selectin.
Barthel, S R +6 more
core +1 more source

