Fucosyltransferases in Schistosoma mansoni development [PDF]
Glycobiology, 2001 Glycoconjugate-bound fucose, abundant in the parasite Schistosoma mansoni, has been found in the form of Fucalpha1,3GlcNAc, Fucalpha1,2Fuc, Fucalpha1,6GlcNAc, and perhaps Fucalpha1,4GlcNAc linkages. Here we quantify fucosyltransferase activities in three developmental stages of S. mansoni.
E T, Marques +5 more
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The role of the mobile proton in fucose migration [PDF]
, 2019 Fucose migration reactions represent a substantial challenge in the analysis of fucosylated glycan structures by mass spectrometry. In addition to the well-established observation of transposed fucose residues in glycan-dissociation product ions, recent ...
Helden, Gert von +7 more
core +1 more source
A new superfamily of protein-O-fucosyltransferases, 2-fucosyltransferases, and 6-fucosyltransferases: phylogeny and identification of conserved peptide motifs [PDF]
Glycobiology, 2003 The presence of three conserved peptide motifs shared by alpha2-fucosyltransferases, alpha6-fucosyltransferases, the protein-O-fucosyltransferase family 1 (POFUT1) and a newly identified protein-O-fucosyltransferase family 2 (POFUT2), together with evidence that the present genes encoding for these enzymes have originated from a common ancestor by ...
Ivan, Martinez-Duncker +4 more
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Viruses, 2020 Innate resistance to viral infections can be attributed to mutations in genes involved in the immune response, or to the receptor/ligand. A remarkable example of the latter is the recently described Mendelian trait resistance to clinically important and ...
Sumit Sharma +3 more
doaj +1 more source
Salmonella Degrades the Host Glycocalyx Leading to Altered Infection and Glycan Remodeling. [PDF]
, 2016 Complex glycans cover the gut epithelial surface to protect the cell from the environment. Invasive pathogens must breach the glycan layer before initiating infection.
Arabyan, Narine +11 more
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C-Terminal Truncation of α 1,6-Fucosyltransferase from Rhizobium Sp. does not Annul the Transferase Activity of the Enzyme [PDF]
, 2002 6 pages.-- PMID: 11814863 [PubMed].Recently we have over-expressed the enzyme a 1,6-fucosyltransferase from Rhizobium sp. in Escherichia coli. In this heterologous system the enzyme was mainly expressed as inclusion bodies and the one that was expressed ...
Bastida, Agatha +2 more
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CHIMIA, 2006 Research over the past two decades has uncovered numerous biological roles for carbohydrates, e.g. in cell adhesion processes, signal transduction, malignant transformation, or viral and bacterial cell-surface recognition.
Said Rabbani +2 more
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The fucose salvage pathway inhibits invadopodia formation and extracellular matrix degradation in melanoma cells. [PDF]
PLoS ONE, 2018 The fucose salvage pathway is a two-step process in which mammalian cells transform L-fucose into GDP-L-fucose, a universal fucose donor used by fucosyltransferases to modify glycans.
Tyler Keeley +4 more
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Human α1,3/4 Fucosyltransferases [PDF]
Journal of Biological Chemistry, 2000 residues, in addition to a free Cys residue that lies near the binding site for GDP-fucose (Holmes, E. H.,
Eric H. Holmes +9 more
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Exploring the diverse biological significance and roles of fucosylated oligosaccharides
Frontiers in Molecular BiosciencesLong since, carbohydrates were thought to be used just as an energy source and structural material. However, in recent years, with the emergence of the field of glycobiology and advances in glycomics, much has been learned about the biological role of ...
Burcu Pekdemir, Sercan Karav
doaj +1 more source