Salmonella Degrades the Host Glycocalyx Leading to Altered Infection and Glycan Remodeling. [PDF]
, 2016 Complex glycans cover the gut epithelial surface to protect the cell from the environment. Invasive pathogens must breach the glycan layer before initiating infection.
Arabyan, Narine +11 more
core +1 more source
Genetic signatures for Helicobacter pylori strains of West African origin. [PDF]
PLoS ONE, 2017 Helicobacter pylori is a genetically diverse bacterial species that colonizes the stomach in about half of the human population. Most persons colonized by H.
Kennady K Bullock +6 more
doaj +1 more source
At the nexus of three kingdoms: the genome of the mycorrhizal fungus Gigaspora margarita provides insights into plant, endobacterial and fungal interactions. [PDF]
, 2020 As members of the plant microbiota, arbuscular mycorrhizal fungi (AMF, Glomeromycotina) symbiotically colonize plant roots. AMF also possess their own microbiota, hosting some uncultivable endobacteria.
Amselem, Joëlle +12 more
core +3 more sources
Exploring the diverse biological significance and roles of fucosylated oligosaccharides
Frontiers in Molecular BiosciencesLong since, carbohydrates were thought to be used just as an energy source and structural material. However, in recent years, with the emergence of the field of glycobiology and advances in glycomics, much has been learned about the biological role of ...
Burcu Pekdemir, Sercan Karav
doaj +1 more source
Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation [PDF]
, 2017 Joint modeling of a number of phenotypes using multivariate methods has often been neglected in genome-wide association studies and if used, replication has not been sought. Modern omics technologies allow characterization of functional phenomena using a
Aulchenko, Yurii S. +14 more
core +3 more sources
α-1,6-Fucosyltransferase Is Essential for Myogenesis in Zebrafish
Cells, 2022 Glycosylation is an important mechanism regulating various biological processes, including intercellular signaling and adhesion. α-1,6-fucosyltransferase (Fut8) belongs to a family of enzymes that determine the terminal structure of glycans. Fut8 is widely conserved from Caenorhabditis elegans to humans, and its mutants have been reported in humans ...
Nozomi Hayashiji +7 more
openaire +3 more sources
GDP-L-fucose : synthesis and role in inflammation [PDF]
, 2007 GDP-L-fucose: synthesis and role in inflammation The migration of leukocytes from intravascular locations to extravascular sites is essential to the immune responses.
Niittymäki, Jaana
core
Sialic acids in biological and therapeutic processes: opportunities and challenges [PDF]
, 2015 It is now well documented that carbohydrates play multiple roles in biological processes, and hence are interesting targets for chemical biology and medicinal chemistry programmes.
Helen MI Osborn +3 more
core +1 more source
Intestinal Barrier Glycosylation for Gut Physiology and Pathology
Barrier Immunity, EarlyView.ABSTRACT The intestinal barrier is a selective structure that safeguards the body from external threats while permitting nutrient absorption and immune surveillance. It consists of the outer mucus layer, the intermediate layer of intestinal epithelial cells (IECs), and the inner layer of immune cells. The proteins in the mucus layer and within IECs are
Girak Kim, Deji Ye, Yikun Yao, Chuan Wu
wiley +1 more source
QTL study reveals candidate genes underlying host resistance in a Red Queen model system.
PLoS Genetics, 2023 Specific interactions of host and parasite genotypes can lead to balancing selection, maintaining genetic diversity within populations. In order to understand the drivers of such specific coevolution, it is necessary to identify the molecular ...
Maridel Fredericksen +4 more
doaj +1 more source