Results 31 to 40 of about 174,095 (266)
Role of sphingolipids in the transport of prosaposin to the lysosomes
Journal of Lipid Research, 1999 Prosaposin is the precursor of four lysosomal saposins that promote the degradation of glycosphingolipids (GSLs) by acidic hydrolases. GSLs contain a hydrophobic ceramide moiety, which acts as a membrane anchor, and a hydrophilic oligosaccharide chain ...
Stephane Lefrancois +4 more
doaj +1 more source
Fumonisin B1: A Tool for Exploring the Multiple Functions of Sphingolipids in Plants
Frontiers in Plant Science, 2020 Fumonisin toxins are produced by Fusarium fungal pathogens. Fumonisins are structural analogs of sphingosine and potent inhibitors of ceramide synthases (CerSs); they disrupt sphingolipid metabolism and cause disease in plants and animals.
Hong-Yun Zeng, Chun-Yu Li, N. Yao
semanticscholar +1 more source
The aflatoxin B1-fumonisin B1 toxicity in BRL-3A hepatocytes is associated to induction of cytochrome P450 activity and arachidonic acid metabolism [PDF]
, 2017 Human oral exposure to aflatoxin B1 (AFB1) and fumonisin B1 (FB1) is associated with increased hepatocellular carcinoma. Although evidence suggested interactive AFB1–FB1 hepatotoxicity, the underlying mechanisms remain mostly unidentified.
Arias, Silvina Lorena +5 more
core +1 more source
Assessment of Human Exposure to Fumonisin B1
Journal of Food Protection, 1998 Fumonisin B1 is currently regarded as the most significant mycotoxin produced by Fusarium spp. It has carcinogenic properties and may play a role in the etiology of human esophageal cancer. The human population is exposed to fumonisin B1 primarily by intake of fumonisin B1-contaminated maize. Maize consumed in the Netherlands is imported from all parts
de Nijs, M +4 more
openaire +5 more sources
Biosensors & bioelectronics, 2020 Compared to the traditional heterogeneous assays, a homogeneous immunoassay is a preferred format for its simplicity. By cloning and isolating luminescent proteins from bioluminescent organisms, bioluminescence has been widely used for various biological
Tawfiq Alsulami +5 more
semanticscholar +1 more source
Toxins, 2015 A high-resolution liquid chromatography-Orbitrap mass spectrometry (LC-Orbitrap MS) method was developed for simultaneous determination of 20 Fusarium toxins (nivalenol, fusarenon-X, deoxynivalenol, 3-acetyl deoxynivalenol, 15-acetyl deoxynivalenol, HT-2
Masayoshi Tamura +5 more
doaj +1 more source
The low intestinal and hepatic toxicity of hydrolyzed fumonisin B1 correlates with its inability to alter the metabolism of sphingolipids [PDF]
, 2012 Fumonisins are mycotoxins frequently found as natural contaminants in maize, where they are produced by the plant pathogen Fusarium verticillioides. They are toxic to animals and exert their effects through mechanisms involving disruption of sphingolipid
Bracarense, Ana-Paula +8 more
core +2 more sources
Türkiye’de Üretilen Mısırlarda Mikotoksin Düzeylerinin ve GDO Varlığının Araştırılması
Turkish Journal of Agriculture: Food Science and Technology, 2019 Ülkemizde mısır üretimindeki artış bir yandan sürerken, bir yandan da dünyada mısırın soyadan sonra en çok genetiği değiştirilmiş ürün olması nedeniyle tüketicinin mısır ile ilgili algısı her geçen gün daha olumsuz olmaktadır.
Sanem Argın, Sibel Şimşek Yazıcı
doaj +1 more source
Integrating gene expression, ecology and mycotoxin production by Fusarium and Aspergillus species in relation to interacting environmental factors [PDF]
, 2016 Environmental factors, such as water availability (water activity, aw), temperature and their interactions, have a significant impact on the life cycle of mycotoxigenic fungi.
Magan, Naresh, Medina-Vayá, Ángel
core +1 more source
Investigation of Naturally Occurring Fumonisin B1 and Glycated Fumonisin B1 in Korean Feedstuffs
Annals of Chromatography and Separation Techniques, 2015 Mycotoxins are potentially dangerous contaminants of livestock feeds. In this study, we measured the levels of fumonisin B1 and glycated fumonisin B1 in feedstuffs and then investigated the ability of the extrusion heating regimen to convert the most prevalent mycotoxin contaminant, fumonisin B1, to a less toxic glycated form.
Jongsung Ahn +2 more
openaire +1 more source