Results 21 to 30 of about 3,632,451 (277)
An Imaging and Systems Modeling Approach to Fibril Breakage Enables Prediction of Amyloid Behavior [PDF]
, 2013 Delineating the nanoscale properties and the dynamic assembly and disassembly behaviors of amyloid fibrils is key for technological applications that use the material properties of amyloid fibrils, as well as for developing treatments of amyloid ...
Xue, Wei-Feng +3 more
core +1 more source
Segmental Polymorphism in a Functional Amyloid [PDF]
Biophysical Journal, 2011 Although amyloid fibrils are generally considered to be causative or contributing agents in amyloid diseases, several amyloid fibrils are also believed to have biological functions. Among these are fibrils formed by Pmel17 within melanosomes, which act as a template for melanin deposition. We use solid-state NMR to show that the molecular structures of
Hu, Kan-Nian +3 more
openaire +2 more sources
Microorganisms, 2021 The pathogen Staphylococcus aureus is recognized as one of the most frequent causes of biofilm-associated infections. The recently identified phenol-soluble modulin (PSM) peptides act as the key molecular effectors of staphylococcal biofilm maturation ...
Masihuz Zaman, Maria Andreasen
doaj +1 more source
Fibril fragmentation in amyloid assembly and cytotoxicity: When size matters [PDF]
, 2010 Amyloid assemblies are associated with several debilitating human disorders. Understanding the intra- and extracellular assembly of normally soluble proteins and peptides into amyloid aggregates and how they disrupt normal cellular functions is therefore
Xue, Wei-Feng +7 more
core +1 more source
Functional Amyloids Signal Their Arrival [PDF]
Science Signaling, 2009 Several peptide and protein hormones are stored in an amyloid configuration in secretory granules.
Matthew P, Badtke +2 more
openaire +2 more sources
Genes Involved in Biofilm Matrix Formation of the Food Spoiler Pseudomonas fluorescens PF07
Frontiers in Microbiology, 2022 The extracellular matrix is essential for the biofilm formation of food spoilers. Pseudomonas fluorescens PF07 is a previous isolate from spoiled marine fish; however, the genes involved in the extracellular matrix formation of PF07 biofilms remain ...
Miao Guo +7 more
doaj +1 more source
Mitochondrial β-amyloid in Alzheimer's disease [PDF]
, 2011 This research is supported by Alzheimer's Research UK, the Wellcome Trust and the Biotechnology and Biological Sciences Research Council.It is well established that the intracellular accumulation of beta-amyloid is associated with Alzheimer’s disease and
Ainge, JA +23 more
core +1 more source
An Amyloid Core Sequence in the Major
mBio, 2019 The human fungal commensal Candida albicans can become a serious opportunistic pathogen in immunocompromised hosts. The C. albicans cell adhesion protein Als1p is a highly expressed member of a large family of paralogous adhesins.
Vida Ho +8 more
doaj +1 more source
Plants, 2021 Plant natriuretic peptides (PNPs) are hormones that have been extracted from many different species, with the Arabidopsis thaliana PNP (AtPNP-A) being the most studied among them.
Georgia I. Nasi +7 more
doaj +1 more source
Destruxin E Decreases Beta-Amyloid Generation by Reducing Colocalization of Beta-Amyloid-Cleaving Enzyme 1 and Beta-Amyloid Protein Precursor [PDF]
, 2009 Alzheimer-disease-associated beta-amyloid (A beta) is produced by sequential endoproteolysis of beta-amyloid protein precursor (beta APP): the extracellular portion is shed by cleavage in the juxtamembrane region by beta-amyloid-cleaving enzyme (BACE ...
Nakano, Yuko +27 more
core +1 more source