Results 31 to 40 of about 308,404 (341)
Functional Amyloids Signal Their Arrival [PDF]
Science Signaling, 2009 Several peptide and protein hormones are stored in an amyloid configuration in secretory granules.
Matthew P, Badtke +2 more
openaire +2 more sources
Early affective changes and increased connectivity in preclinical Alzheimer's disease. [PDF]
, 2018 IntroductionAffective changes precede cognitive decline in mild Alzheimer's disease and may relate to increased connectivity in a "salience network" attuned to emotionally significant stimuli.
Bilgel, Murat +7 more
core +1 more source
Plants, 2021 Plant natriuretic peptides (PNPs) are hormones that have been extracted from many different species, with the Arabidopsis thaliana PNP (AtPNP-A) being the most studied among them.
Georgia I. Nasi +7 more
doaj +1 more source
Measuring cortical connectivity in Alzheimer's disease as a brain neural network pathology: Toward clinical applications [PDF]
, 2016 Objectives: The objective was to review the literature on diffusion tensor imaging as well as resting-state functional magnetic resonance imaging and electroencephalography (EEG) to unveil neuroanatomical and neurophysiological substrates of Alzheimer ...
BABILONI, CLAUDIO +6 more
core +1 more source
Amyloids — a functional coat for microorganisms [PDF]
Nature Reviews Microbiology, 2005 Amyloids are filamentous protein structures approximately 10 nm wide and 0.1-10 mum long that share a structural motif, the cross-beta structure. These fibrils are usually associated with degenerative diseases in mammals. However, recent research has shown that these proteins are also expressed on bacterial and fungal cell surfaces.
Gebbink, M.F.B.G. +4 more
openaire +3 more sources
Molecules, 2022 TIR-domain-containing adapter-inducing interferon-β (TRIF) is an innate immune protein that serves as an adaptor for multiple cellular signalling outcomes in the context of infection. TRIF is activated via ligation of Toll-like receptors 3 and 4.
Max O. D. G. Baker +7 more
doaj +1 more source
Why musical memory can be preserved in advanced Alzheimer's disease [PDF]
, 2015 Musical memory is relatively preserved in Alzheimer's disease and other dementias. In a 7 Tesla functional MRI study employing multi-voxel pattern analysis, Jacobsen et al.
Chételat, Gael +4 more
core +2 more sources
Epigallocatechin Gallate Remodelling of Hfq Amyloid-Like Region Affects Escherichia coli Survival
Pathogens, 2018 Hfq is a pleiotropic regulator that has key roles in the control of genetic expression. The protein noticeably regulates translation efficiency and RNA decay in Gram-negative bacteria, due to the Hfq-mediated interaction between small regulatory ...
David Partouche +7 more
doaj +1 more source
Fold modulating function: bacterial toxins to functional amyloids [PDF]
Frontiers in Microbiology, 2014 Many bacteria produce cytolytic toxins that target host cells or other competing microbes. It is well known that environmental factors control toxin expression, however, recent work suggests that some bacteria manipulate the fold of these protein toxins to control their function.
Syed, Adnan K., Boles, Blaise R.
openaire +3 more sources
Prions, prionoid complexes and amyloids: the bad, the good and something in between
Swiss Medical Weekly, 2017 Prions are infectious agents causing transmissible spongiform encephalopathies in humans and animals. These protein-based particles template conformational changes in a host-encoded prion protein to an insoluble self-like conformation.
Iva Hafner-Bratkovič
doaj +1 more source