Results 1 to 10 of about 1,155,621 (272)
In Situ Characterization of Hfq Bacterial Amyloid: A Fourier-Transform Infrared Spectroscopy Study [PDF]
Pathogens, 2019 Hfq is a bacterial protein that regulates gene expression at the post-transcriptional level in Gram-negative bacteria. We have previously shown that Escherichia coli Hfq protein, and more precisely its C-terminal region (CTR), self-assembles into an ...
David Partouche +5 more
doaj +6 more sources
Accelerated Amyloid Beta Pathogenesis by Bacterial Amyloid FapC [PDF]
Advanced Science, 2020 The gut–brain axis has attracted increasing attention in recent years, fueled by accumulating symptomatic, physiological, and pathological findings. In this study, the aggregation and toxicity of amyloid beta (Aβ), the pathogenic peptide associated with ...
Ibrahim Javed +10 more
doaj +11 more sources
Identification and characterization of the Hfq bacterial amyloid region DNA interactions [PDF]
BBA Advances, 2021 Nucleic acid amyloid proteins interactions have been observed in the past few years. These interactions often promote protein aggregation. Nevertheless, molecular basis and physiological consequences of these interactions are still poorly understood ...
Florian Turbant +6 more
doaj +4 more sources
Bacterial Extracellular DNA Promotes β-Amyloid Aggregation [PDF]
Microorganisms, 2021 Alzheimer’s disease is associated with prion-like aggregation of the amyloid β (Aβ) peptide and the subsequent accumulation of misfolded neurotoxic aggregates in the brain.
George Tetz, Victor Tetz
doaj +5 more sources
Molecules, 2022 Functional amyloid is produced by many organisms but is particularly well understood in bacteria, where proteins such as CsgA (E. coli) and FapC (Pseudomonas) are assembled as functional bacterial amyloid (FuBA) on the cell surface in a carefully ...
Thorbjørn Vincent Sønderby +2 more
doaj +3 more sources
Surveillance of Amyloid Deposition and Bacterial Contamination in Chicken Liver from Meat Market
The Journal of Poultry Science, 2014 From the standpoint of poultry meat hygiene, amyloid deposition and bacterial contamination in livers of 197 mature white layer chickens from a slaughterhouse and 100 young broiler breeder chickens from 5 different retail butcher shops were examined ...
Naotaka Ishiguro +3 more
doaj +3 more sources
Functional bacterial amyloid increases Pseudomonas biofilm hydrophobicity and stiffness [PDF]
Frontiers in Microbiology, 2015 The success of Pseudomonas species as opportunistic pathogens derives in great part from their ability to form stable biofilms that offer protection against chemical and mechanical attack.
Guanghong eZeng +8 more
doaj +2 more sources
QRB Discovery, 2022 Interactions between proteins and single-stranded DNA (ssDNA) are crucial for many fundamental biological processes, including DNA replication and genetic recombination.
Krzysztof Kubiak +10 more
doaj +1 more source
The Amyloid Region of Hfq Riboregulator Promotes DsrA:rpoS RNAs Annealing
Biology, 2021 Hfq is a bacterial RNA chaperone which promotes the pairing of small noncoding RNAs to target mRNAs, allowing post-transcriptional regulation. This RNA annealing activity has been attributed for years to the N-terminal region of the protein that forms a ...
Florian Turbant +3 more
doaj +1 more source
Apomorphine Targets the Pleiotropic Bacterial Regulator Hfq
Antibiotics, 2021 Hfq is a bacterial regulator with key roles in gene expression. The protein notably regulates translation efficiency and RNA decay in Gram-negative bacteria, thanks to its binding to small regulatory noncoding RNAs. This property is of primary importance
Florian Turbant +6 more
doaj +1 more source