Results 41 to 50 of about 308,404 (341)
Calcium in the initiation, progression and as an effector of Alzheimer's disease pathology. [PDF]
, 2009 The cause(s) of sporadic Alzheimer's disease (sAD) are complex and currently poorly understood. They likely result from a combination of genetic, environmental, proteomic and lipidomic factors that crucially occur only in the aged brain.
Green, Kim N
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Force Sensitivity in
mSphere, 2016 Many fungal adhesins have short, β-aggregation-prone sequences that play important functional roles, and in the Candida albicans adhesin Als5p, these sequences cluster the adhesins after exposure to shear force.
Cho X. J. Chan +6 more
doaj +1 more source
Proteinopathy, oxidative stress and mitochondrial dysfunction: cross talk in alzheimer’s disease and parkinson’s disease [PDF]
, 2017 Alzheimer's disease and Parkinson's disease are two common neurodegenerative diseases of the elderly people that have devastating effects in terms of morbidity and mortality.
Chakrabarti, S. +3 more
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Frontiers in Aging Neuroscience, 2021 Objective: Amnesia in Alzheimer's disease (AD) appears early and could be caused by encoding deficiency, consolidation dysfunction, and/or impairment in the retrieval of stored memory information. The relationship between AD pathology biomarker β-amyloid
Binyin Li +14 more
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Manipulation of lipid rafts in neuronal cells [PDF]
, 2010 Lipid rafts are specialized plasma membrane micro-domains highly enriched in cholesterol, sphingolipids and glycosylphosphatidylinositol (GPI) anchored proteins.
Eckert, Gunter P.
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An Amyloid Core Sequence in the Major
mBio, 2019 The human fungal commensal Candida albicans can become a serious opportunistic pathogen in immunocompromised hosts. The C. albicans cell adhesion protein Als1p is a highly expressed member of a large family of paralogous adhesins.
Vida Ho +8 more
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AmyPro: a database of proteins with validated amyloidogenic regions [PDF]
, 2017 Soluble functional proteins may transform into insoluble amyloid fibrils that deposit in a variety of tissues. Amyloid formation is a hallmark of age-related degenerative disorders.
De Baets, G. +4 more
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eLife, 2022 Synergistic-aggregation and cross-seeding by two different proteins/peptides in the amyloid aggregation are well evident in various neurological disorders including Alzheimer’s disease.
Debdeep Chatterjee +16 more
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Hypoxic regulation of ion channel function and expression [PDF]
, 2002 Acute hypoxia regulates the activity of specific ion channels in a rapid and reversible manner. Such effects underlie appropriate cellular responses to hypoxia which are designed to initiate cardiorespiratory reflexes and contribute importantly to other ...
Peers, C.
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The Sheaths of Methanospirillum Are Made of a New Type of Amyloid Protein
Frontiers in Microbiology, 2018 The genera Methanospirillum and Methanosaeta contain species of anaerobic archaea that grow and divide within proteinaceous tubular sheaths that protect them from environmental stressors.
Line Friis Bakmann Christensen +6 more
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