Results 51 to 60 of about 769,889 (306)
International Journal of Molecular Sciences, 2023 B-cell receptor (BCR) is a B cell hallmark surface complex regulating multiple cellular processes in normal as well as malignant B cells. Igα (CD79a)/Igβ (CD79b) are essential components of BCR that are indispensable for its functionality, signal ...
Anton Tkachenko, K. Kupcova, O. Havranek
semanticscholar +1 more source
Traumatic Brain Injury Induces Genome-Wide Transcriptomic, Methylomic, and Network Perturbations in Brain and Blood Predicting Neurological Disorders. [PDF]
, 2017 The complexity of the traumatic brain injury (TBI) pathology, particularly concussive injury, is a serious obstacle for diagnosis, treatment, and long-term prognosis. Here we utilize modern systems biology in a rodent model of concussive injury to gain a
Agrawal, Rahul +5 more
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Science Advances, 2019 Bcl11b orchestrates a Treg cell transcription program by regulating functional recruitment of the master regulator Foxp3. Foxp3 and its protein partners establish a regulatory T (Treg) cell transcription profile and promote immunological tolerance ...
S. Hasan +7 more
semanticscholar +1 more source
Validating an artificial organelle: Studies of lipid droplet-specific proteins on adiposome platform
iScience, 2021 Summary: New strategies are urgently needed to characterize the functions of the lipid droplet (LD). Here, adiposome, an artificial LD mimetic platform, was validated by comparative in vitro bioassays.
Xuejing Ma +5 more
doaj +1 more source
Recombinant GPI-anchored TIMP-1 stimulates growth and migration of peritoneal mesothelial cells. [PDF]
, 2012 Mesothelial cells are critical in the pathogenesis of post-surgical intraabdominal adhesions as well as in the deterioration of the peritoneal membrane associated with long-term peritoneal dialysis.
Djafarzadeh, Roghieh +10 more
core +5 more sources
The various routes to functional regeneration in the central nervous system [PDF]
, 2020 © The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Echeverri, K.
Echeverri, Karen
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iScience, 2023 Summary: Misfolded glycoprotein recognition and endoplasmic reticulum (ER) retention are mediated by the ER glycoprotein folding quality control (ERQC) checkpoint enzyme, UDP-glucose glycoprotein glucosyltransferase (UGGT). UGGT modulation is a promising
Kevin P. Guay +27 more
doaj +1 more source
GSDME-Dependent Incomplete Pyroptosis Permits Selective IL-1α Release under Caspase-1 Inhibition
iScience, 2020 Summary: Pyroptosis is a form of regulated cell death that is characterized by gasdermin processing and increased membrane permeability. Caspase-1 and caspase-11 have been considered to be essential for gasdermin D processing associated with inflammasome
Emi Aizawa +11 more
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Poroptosis: A form of cell death depending on plasma membrane nanopores formation
iScience, 2022 Summary: Immunogenic cell death (ICD) in malignant cells can decrease tumor burden and activate antitumor immune response to obtain lasting antitumor immunity, leading to the elimination of distant metastases and prevention of recurrence. Here, we reveal
Hao Li +9 more
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Receptor uptake arrays for vitamin B12, siderophores and glycans shape bacterial communities
, 2017 Molecular variants of vitamin B12, siderophores and glycans occur. To take up variant forms, bacteria may express an array of receptors. The gut microbe Bacteroides thetaiotaomicron has three different receptors to take up variants of vitamin B12 and 88 ...
Frank, Steven A.
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