Results 31 to 40 of about 3,358,253 (225)

Update on the treatment navigation for functional cure of chronic hepatitis B: Expert consensus 2.0 [PDF]

Clinical and Molecular Hepatology
As new evidence emerges, treatment strategies toward the functional cure of chronic hepatitis B are evolving. In 2019, a panel of national hepatologists published a Consensus Statement on the functional cure of chronic hepatitis B.
Di Wu, Jia-Horng Kao, Teerha Piratvisuth, Xiaojing Wang, Patrick T.F. Kennedy, Motoyuki Otsuka, Sang Hoon Ahn, Yasuhito Tanaka, Guiqiang Wang, Zhenghong Yuan, Wenhui Li, Young-Suk Lim, Junqi Niu, Fengmin Lu, Wenhong Zhang, Zhiliang Gao, Apichat Kaewdech, Meifang Han, Weiming Yan, Hong Ren, Peng Hu, Sainan Shu, Paul Yien Kwo, Fu-sheng Wang, Man-Fung Yuen, Qin Ning   +25 more
doaj   +1 more source

Pan-Immune-Inflammation Value and Functional Cure in Patients with Chronic Hepatitis B Receiving Long-Term Nucleos(t)ide Analogue Therapy

Viral Hepatitis Journal
Objectives: Functional cure, defined by hepatitis B surface antigen loss, is the preferred therapeutic endpoint in chronic hepatitis B (CHB). The pan-immune-inflammation value (PIV) is an inflammation-based index derived from routine complete blood count
Aslı Vatan
doaj   +1 more source

Seroreversion and Acute Decompensation in Chronic Hepatitis B after Discontinuation of Oral Nucleotide Analog in the Patients Achieving HBsAg Loss

The Korean Journal of Gastroenterology, 2020
Although rare patients with chronic hepatitis B can achieve HBsAg loss on oral nucleos(t)ide analog (NA), the optimal timing of stopping oral NAs safely has been considered when HBsAg and HBV DNA are negative in the serum because HBsAg loss induced by ...
Hye Jeong Cho, Seung Kak Shin, Oh Sang Kwon, Ju Hyun Kim, Yun Soo Kim   +4 more
doaj   +1 more source

Retinol Binding Protein 4 reactivates latent HIV-1 by triggering canonical NF-κB, JAK/STAT5 and JNK signalling

Signal Transduction and Targeted Therapy
Reactivation of the latent viral reservoirs is crucial for a cure of HIV/AIDS. However, current latency reversing agents are inefficient, and the endogenous factors that have the potential to reactivate HIV in vivo remain poorly understood.
Chiara Pastorio, Khumoekae Richard, Shariq Usmani, Ann-Kathrin Kissmann, Grigory Bolotnikov, Guillermo Gosálbez, Manuel Hayn, Lennart Koepke, Alina Sauertnik, Andrea Preising, Nico Preising, Ludger Ständker, Matthew Fair, Jessicamarie Morris, Emmanouil Papasavvas, Qin Liu, Honghong Sun, Armando Rodríguez, Karam Mounzer, Sebastian Wiese, Pablo Tebas, Yangzhu Du, Gregory M. Laird, Markus Jaritz, Frank Rosenau, Moritz M. Gaidt, Konstantin M. J. Sparrer, Luis J. Montaner, Frank Kirchhoff   +28 more
doaj   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Spatially-resolved volume monitoring of adhesive cure using correlated-image optical coherence tomography [PDF]

, 2013
Cross-correlation of optical coherence tomography (OCT) images has been applied to internal imaging of PVA and two-part epoxy adhesives during cure, providing information on relative viscosity at different positions within the sample volume.
Tatam, Ralph P., Ford, Helen D.
core   +1 more source

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko, Segev Gabay, Jonathan Roth, Amit Ringel, Rina Dvir, Shlomi Constantini   +5 more
wiley   +1 more source

Exercise Capacity, Physical Activity, Fatigue, and Neurocognitive Function in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess, Gustaf Glavå, Simon Skau, Hans‐Georg Kuhn, Maria Bäck, Marianne Jarfelt   +5 more
wiley   +1 more source

Neurocognitive, School‐Based, and Quality of Life Outcomes for Youth With Sickle Cell Disease and Thalassemia: A Scoping Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT The medical burdens of sickle cell disease (SCD) and transfusion‐dependent β‐thalassemia (TDT) are chronic and cumulative, even in children. Yet the effects expand beyond medications and healthcare visits due to their impacts on school attendance, academic performance, and peer engagement.
Mary Ann Etling, Hakim Tokhi, Alexander A. Boucher   +2 more
wiley   +1 more source

In-situ cure monitoring of epoxy resin systems [PDF]

, 1998
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This thesis describes the work carried out at Brunel University to develop novel optical fibre sensors capable of monitoring the cure state of an epoxy ...
Powell, Graham
core   +7 more sources