Results 51 to 60 of about 412,466 (343)

Vitamin D3 receptor is highly expressed in Hodgkin's lymphoma [PDF]

open access: yes, 2012
Background: Hodkin s lymphoma is one of the most frequent lymphoma in western world. Despite an overall good prognosis some patients suffer relapsing tumors which are difficult to cure.
Benz, Alexander   +2 more
core   +2 more sources

HIV therapeutic vaccines: moving towards a functional cure [PDF]

open access: yesCurrent Opinion in Immunology, 2015
Anti-viral T-cell and B-cell responses play a crucial role in suppressing HIV and SIV replication during chronic infection. However, these infections are rarely controlled by the host immune response, and most infected individuals need lifelong antiretroviral therapy (ART).
Geetha H, Mylvaganam   +2 more
openaire   +2 more sources

Fabrication of functional microstructured optical fibers through a selective-filling technique [PDF]

open access: yes, 2004
We develop a method for the fabrication of functional microstructured optical fibers (MOFs) by selectively filling the air holes with liquid phase materials, where we utilize the dependence of filling speed on the size of the air holes.
Huang, Yanyi, Xu, Yong, Yariv, Amnon
core   +1 more source

Latency function estimation under the mixture cure model when the cure status is available

open access: yesLifetime Data Analysis, 2023
This paper addresses the problem of estimating the conditional survival function of the lifetime of the subjects experiencing the event (latency) in the mixture cure model when the cure status information is partially available. The approach of past work relies on the assumption that long-term survivors are unidentifiable because of right censoring ...
Wende Clarence Safari   +2 more
openaire   +4 more sources

Gene function in schistosomes: recent advances towards a cure [PDF]

open access: yesFrontiers in Genetics, 2015
Schistosomes are human parasites distributed worldwide in tropical and sub-tropical latitudes, especially in developing countries and impoverished regions. These neglected tropical disease (NTD) pathogens causes debilitating illnesses, which include hepatosplenomegaly, hepatic fibrosis, haemorrhagic necrotic ulcerations in the intestinal mucosa ...
Arnon Dias Jurberg   +2 more
openaire   +5 more sources

Telling Cause from Effect using MDL-based Local and Global Regression [PDF]

open access: yes, 2017
We consider the fundamental problem of inferring the causal direction between two univariate numeric random variables $X$ and $Y$ from observational data.
Marx, Alexander, Vreeken, Jilles
core   +2 more sources

Cold-Curing Structural Epoxy Resins: Analysis of the Curing Reaction as a Function of Curing Time and Thickness [PDF]

open access: yesMaterials, 2014
The curing reaction of a commercial cold-curing structural epoxy resin, specifically formulated for civil engineering applications, was analyzed by thermal analysis as a function of the curing time and the sample thickness. Original and remarkable results regarding the effects of curing time on the glass transition temperature and on the residual heat ...
ESPOSITO CORCIONE, Carola   +2 more
openaire   +2 more sources

Drug Discovery Study Aimed at a Functional Cure for HBV

open access: yesViruses, 2022
Hepatitis B virus (HBV) causes acute and, most importantly, chronic hepatitis B worldwide. Antiviral treatments have been developed to reduce viral loads but few patients with chronic hepatitis B (CHB) achieve a functional cure.
Takehisa Watanabe   +2 more
doaj   +1 more source

Retinol Binding Protein 4 reactivates latent HIV-1 by triggering canonical NF-κB, JAK/STAT5 and JNK signalling

open access: yesSignal Transduction and Targeted Therapy
Reactivation of the latent viral reservoirs is crucial for a cure of HIV/AIDS. However, current latency reversing agents are inefficient, and the endogenous factors that have the potential to reactivate HIV in vivo remain poorly understood.
Chiara Pastorio   +28 more
doaj   +1 more source

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