Results 71 to 80 of about 155,433 (279)

Seroreversion and Acute Decompensation in Chronic Hepatitis B after Discontinuation of Oral Nucleotide Analog in the Patients Achieving HBsAg Loss

The Korean Journal of Gastroenterology, 2020
Although rare patients with chronic hepatitis B can achieve HBsAg loss on oral nucleos(t)ide analog (NA), the optimal timing of stopping oral NAs safely has been considered when HBsAg and HBV DNA are negative in the serum because HBsAg loss induced by ...
Hye Jeong Cho, Seung Kak Shin, Oh Sang Kwon, Ju Hyun Kim, Yun Soo Kim   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Challenges in HIV vaccine research for treatment and prevention

Frontiers in Immunology, 2014
Many attempts have been made or are ongoing for HIV prevention and HIV cure. Many successes are in the list, particularly for HIV drugs, recently proposed also for prevention.
Barbara eEnsoli, Aurelio eCafaro, Paolo eMonini, Simone eMarcotullio, Fabrizio eEnsoli   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Quantitatively Evaluate the Improvement of Functional Cure for the Quality of Life of Chronic Hepatitis B Cases: Evidence from a Cross-Sectional Study in China. [PDF]

Healthcare (Basel)
Background: Functional cure of chronic hepatitis B (CHB) can be achieved with appropriate antiviral treatment. However, few studies have evaluated the added benefits of achieving functional cure.
Zhang S, Gao Z, Li H, Kang Y, Fu L, Chen X, Xu X, Chen X, Zhuang H, Zheng H, Cui F.   +10 more
europepmc   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

FLIC - a functional language intermediate code [PDF]

FLIC is a Functional Language Intermediate Code, intended to provide a common intermediate language between diverse implementations of functional languages, including parallel ones.
Joy, Mike, Peyton-Jones, S. L.
core  

Association of hepatitis B core antibody level and hepatitis B surface antigen clearance in HBeAg-negative patients with chronic hepatitis B

Virulence
Predicting hepatitis B surface antigen (HBsAg) clearance is important for chronic hepatitis B (CHB) patients receiving pegylated interferon-alfa (Peg-IFN) therapy.
Jian Wang, Zhiyi Zhang, Li Zhu, Qing Zhang, Shaoqiu Zhang, Yifan Pan, Jiacheng Liu, Fei Cao, Tao Fan, Ye Xiong, Shengxia Yin, Xiaomin Yan, Yuxin Chen, Chuanwu Zhu, Jie Li, Xingxiang Liu, Chao Wu, Rui Huang   +17 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

In-situ cure monitoring of epoxy resin systems

, 1998
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This thesis describes the work carried out at Brunel University to develop novel optical fibre sensors capable of monitoring the cure state of an epoxy ...
Powell, Graham
core