Results 61 to 70 of about 155,433 (279)
Curing Behavior of a Nanocomposite as a Function of Polymerization Procedure
Dental Materials Journal, 2005 The purpose of this study was to analyze the curing behavior of a nanocomposite by assessing in real time the degree of cure at depths of 2 mm and 6 mm. The variation of hardness with depth, shrinkage stress, and curing time until gelation with 16 curing regimes was further investigated using one halogen and three LED curing units. In the present study,
ILIE, Nicoleta +3 more
openaire +3 more sources
Latency function estimation under the mixture cure model when the cure status is available
Lifetime Data Analysis, 2023 This paper addresses the problem of estimating the conditional survival function of the lifetime of the subjects experiencing the event (latency) in the mixture cure model when the cure status information is partially available. The approach of past work relies on the assumption that long-term survivors are unidentifiable because of right censoring ...
Wende Clarence Safari +2 more
openaire +4 more sources
Enhancing functional cure in patients with chronic hepatitis B infection
, 2021 Chronic hepatitis B infection affects 292 million people globally, and is a major risk factor of liver-related diseases. With the existing treatment by either nucleos(t)ide reverse transcriptase inhibitor (NRTI) or pegylated interferon, we can achieve on-
Mak, LY
core
Frontiers in Immunology, 2018 Human immunodeficiency virus (HIV) establishes life-long latency in infected individuals. Although highly active antiretroviral therapy (HAART) has had a significant impact on the course of HIV infection leading to a better long-term outcome, the pool of
Jeffy George, Joseph J. Mattapallil
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
HIV-2 as a model to identify a functional HIV cure [PDF]
, 2019 Two HIV virus types exist: HIV-1 is pandemic and aggressive, whereas HIV-2 is confined mainly to West Africa and less pathogenic. Despite the fact that it has been almost 40 years since the discovery of AIDS, there is still no cure or vaccine against HIV.
da Silva, Z.J. +36 more
core +2 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
, 2019 Introduction The search for an HIV cure involves important behavioural and social processes that complement the domains of biomedicine. However, the field has yet to tap into the full potential of behavioural and social sciences research (BSSR).
Dubé, K. +3 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source