Results 81 to 90 of about 412,466 (343)
Hybrid Manufacturing: Integrating Direct Write and Stereolithography [PDF]
, 2005 A commercial stereolithography (SL) machine was modified to integrate fluid dispensing or direct-write (DW) technology with SL in an integrated manufacturing environment for automated and efficient hybrid manufacturing of complex electrical devices ...
Chavez, Bart +8 more
core
Toward a constitutive model for cure dependent modulus of a high temperature epoxy during the cure [PDF]
, 2010 A constitutive model, based on Kohlrausch-Williams-Watts (KWW) equations, was developed to simulate the evolution of the dynamic relaxation modulus during the cure of a "high temperature' epoxy.
Partridge, Ivana K. +2 more
core +1 more source
Sustainable and equivalent improvements in symptoms and functional
, 2022 Donna M. Evon +7 more
openalex +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Interdisciplinary MedicineHepatitis B virus (HBV) infection represents a significant global public health threat, often progressing to severe complications such as liver cirrhosis and hepatocellular carcinoma (HCC).
Yaru Shi, Rong Fan
doaj +1 more source
The Korean Journal of Gastroenterology, 2020 Although rare patients with chronic hepatitis B can achieve HBsAg loss on oral nucleos(t)ide analog (NA), the optimal timing of stopping oral NAs safely has been considered when HBsAg and HBV DNA are negative in the serum because HBsAg loss induced by ...
Hye Jeong Cho +4 more
doaj +1 more source
Engineering T Cells to Functionally Cure HIV-1 Infection [PDF]
Molecular Therapy, 2015 Despite the ability of antiretroviral therapy to minimize human immunodeficiency virus type 1 (HIV-1) replication and increase the duration and quality of patients' lives, the health consequences and financial burden associated with the lifelong treatment regimen render a permanent cure highly attractive.
Leibman, Rachel S, Riley, James L
openaire +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Targeting the latent reservoir to achieve functional HIV cure [PDF]
F1000Research, 2016 While highly active anti-retroviral therapy has greatly improved the lives of HIV-infected individuals, current treatments are unable to completely eradicate the virus. This is due to the presence of HIV latently infected cells which harbor transcriptionally silent HIV.
Cary, Daniele C., Peterlin, B. Matija
openaire +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source