Results 51 to 60 of about 1,916,984 (295)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Highlights of the Didymellaceae: A polyphasic approach to characterise Phoma and related pleosporalean genera [PDF]

, 2010
Fungal taxonomists routinely encounter problems when dealing with asexual fungal species due to poly- and paraphyletic generic phylogenies, and unclear species boundaries. These problems are aptly illustrated in the genus Phoma.
Gruyter, H., de, Woudenberg, J., Crous, P.W., de Gruyter, H., de Gruyter, J., J. de Gruyter, Aveskamp, M.M., Verkley, G., J.H.C. Woudenberg, M.M. Aveskamp, Verkley, G.J.M., Gruyter, J., de, G.J.M. Verkley, P.W. Crous, Woudenberg, J.H.C.   +14 more
core   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

SWI/SNF complex-mediated chromatin remodeling in Candida glabrata promotes immune evasion

iScience
Summary: Immune evasion is critical for fungal virulence. However, how the human opportunistic pathogen Candida glabrata (Cg) accomplishes this is unknown. Here, we present the first genome-wide nucleosome map of the macrophage-internalized Cg consisting
Kundan Kumar, Aditi Pareek, Rupinder Kaur   +2 more
doaj   +1 more source

Human CLPP reverts the longevity phenotype of a fungal ClpP deletion strain [PDF]

, 2013
Mitochondrial maintenance crucially depends on the quality control of proteins by various chaperones, proteases and repair enzymes. While most of the involved components have been studied in some detail, little is known on the biological role of the ...
Fischer, Fabian, Hamann, Andrea, Weil, Andrea, Osiewacz, Heinz D.   +3 more
core   +1 more source

Nature‐Derived Chitosan Biopolymer: A Promising Candidate for Sustainable Electronics

Advanced Materials Technologies, EarlyView.
In the creation of environmentally friendly devices, nature‐derived chitosan biopolymer is a promising contender for sustainable electronic research. It can be utilized to create more ecologically friendly scalable gadgets and has a variety of uses in different active layers of electronics.
Joshua McDonald, Ali Nawaz, Amandeep Singh, Prashant Sonar   +3 more
wiley   +1 more source

Protocol for determination of phosphatidylinositol 3-phosphate levels and localization in Candida glabrata by confocal microscopy

STAR Protocols
Summary: Phosphatidylinositol 3-phosphate (PI3P) levels govern membrane trafficking in Candida glabrata. Here, we present a confocal imaging-based protocol for PI3P localization analysis using the GFP-FYVE (found in Fab1, YOTB, Vac1, and EEA1) fusion ...
Fizza Askari, Rupinder Kaur
doaj   +1 more source

Internal Transcribed Spacer (ITS) as Dna Barcoding to Identify Fungal Species: a Review

Squalen, 2016
Despite the fact that fungi are important sources of both bioactive compounds and mycotoxins, and that they are very ubiquitous in our environment, their species identification is hampered by incomplete and often unclear literature.
Nurrahmi Dewi Fajarningsih
doaj   +1 more source

The Effectiveness of PCR in Diagnosis of Fungal Keratitis

Oftalʹmologiâ, 2020
Fungi implicated in mycotic keratitis include different species. Conventional methods for the diagnosis of fungal keratitis include staining of corneal scarpings, culture medium (Sabouraud agar) for isolating fungi.Purpose.
G. I. Krichevskaya, L. A. Kovaleva, I. D. Zyurnyayeva, P. V. Makarov, A. E. Andryushin   +4 more
doaj   +1 more source

Spatial structure of fungal DNA assemblages revealed with eDNA metabarcoding in a forest river network in western Japan [PDF]

Metabarcoding and Metagenomics, 2019
Growing evidence has revealed high diversity and spatial heterogeneity of fungal communities in local habitats of terrestrial ecosystems. Recently, the analysis of environmental DNA has been undertaken to study the biodiversity of organisms, such as ...
Shunsuke Matsuoka, Yoriko Sugiyama, Hirotoshi Sato, Izumi Katano, Ken Harada, Hideyuki Doi   +5 more
doaj   +3 more sources