The Health Benefits of Grapefruit Furanocoumarins [PDF]
Although contraindicated for certain medications, grapefruits are also known for their numerous health benefits. Both these effects come from, in part, natural chemicals called furanocoumarin.
Yu Wang, Laura E. Reuss
doaj +10 more sources
Anticancer Potential of Furanocoumarins: Mechanistic and Therapeutic Aspects [PDF]
Cancer is one of the most extreme medical conditions in both developing and developed countries around the world, causing millions of deaths each year. Chemotherapy and/or radiotherapy are key for treatment approaches, but both have numerous adverse health effects.
Salman Ahmed +5 more
core +9 more sources
Isolation of furanocoumarins from Pastinaca sativa L. callus culture
Four furanocoumarins: bergapten, xanthotoxin, isopimpinellin (linear furanocoumarins) and sphondin (angular furanocoumarin) were isolated for the first time from callus tissues of Pastinaca sativa L.(Apiaceae) cultured in vitro on solid medium.
Halina Ekiert, Wanda Kisiel
doaj +2 more sources
Obtaining emulsions of furanocoumarins from Sosnowsky’s hogweed and in vitro assessment of their phototoxic effect [PDF]
Background. Furanocoumarin-based drugs are used for photochemotherapy of various diseases. Sosnovsky’s hogweed can be an available source of furanocoumarins for the development of drugs.The aim of the study.
V. I. Shlyapkina +5 more
doaj +2 more sources
Coumarins and alkaloids in shoot culture of Ruta graveolens L.
A shoot culture of Ruta graveolens L. (Rutaceae) was maintained in the stationary liquid phase. From the cultured shoots seven compounds were isolated and identified as psoralen, bergapten, xanthotoxin, isopimpinellin (linear furanocoumarins), rutamarin (
Halina Ekiert, Wanda Kisiel
doaj +3 more sources
Extraction, Isolation, and Purification of Furanocoumarins from Invasive Heracleum sosnowskyi
Heracleum sosnowskyi Manden. (Sosnowsky’s hogweed), originally introduced to Central and Eastern Europe as a fodder crop, has become a highly invasive species due to its ecological adaptability, high reproductive capacity, and efficient seed dispersal ...
Vida Vickackaite +2 more
doaj +2 more sources
Challenges in the Heterologous Production of Furanocoumarins in Escherichia coli [PDF]
Coumarins and furanocoumarins are plant secondary metabolites with known biological activities. As they are present in low amounts in plants, their heterologous production emerged as a more sustainable and efficient approach to plant extraction. Although
Joana L. Rodrigues +2 more
doaj +2 more sources
Biological Activity Evaluation Against Fusarium oxysporum, Fusarium circinatum, and Meloidogyne incognita of Bioactives-Enriched Extracts of Ruta graveolens L. [PDF]
Ruta graveolens L. has been described as possessing antifungal and nematicidal activity. Among the bioactive compounds present in this plant, alkaloids and furanocoumarins have attracted considerable attention.
Lorena Reyes-Vaquero +5 more
doaj +2 more sources
Leaf furanocoumarins of Heracleum lanatum
Abstract Sphondin is the principal furanocoumarin of Heracleum lanatum leaves; pimpinellin, isopimpinellin, bergapten, xanthotoxin, isobergapten, psoralen and angelicin were also identified. At least eleven other furanocoumarins were present.
P. Botek +3 more
openaire +3 more sources
Valorization of Ficus carica Pruning Residues as Selective Botanical Insecticides: Optimized Furanocoumarin Extraction, Efficacy Against Neotropical Stink Bugs, and Mechanistic Insights via Molecular Docking. [PDF]
Optimized extracts from Ficus carica pruning waste exhibit strong biological activity against major stink bug pests. Complementary in silico analyses suggest this efficacy relies on pest‐specific acetylcholinesterase inhibition, predicting a promising, pollinator‐safe alternative for sustainable agriculture.
Almeida TA +7 more
europepmc +2 more sources

