Evaluating the Anticancer and Anti-Angiogenic Efficacy of Bergaptol in 2D and 3D Tumor Microtissue Models. [PDF]
Chem BiodiversBergaptol induced cell viability inhibition, apoptosis, and cell cycle arrest in HeLa, MDA‐MB‐231, and HepG2 cancer cell lines. Furthermore, it reduced cell viability and suppressed angiogenesis in multicellular microtissues composed of cancer, endothelial, and fibroblast cells.
Bekar B, Sevim Akan H.
europepmc +2 more sources
Phytochemical characterisation of two news blood grapefruits by means of HPLC-MS
Food Chemistry Advances, 2022 In this study, the main flavanones, polymethoxyflavones, anthocyanins and furanocoumarins were evaluated in two blood grapefruits (CQP 31 and CQP 32), in their juice, peel, and leaves, by means of HPLC-DAD analysis and identified by HPLC-MS-MS.
José Antonio del Río +5 more
doaj +1 more source
Oxypeucedanin: Chemotaxonomy, Isolation, and Bioactivities
Plants, 2021 The present review comprehensively gathered phytochemical, bioactivity, and pharmacokinetic reports on a linear furanocoumarin, namely oxypeucedanin. Oxypeucedanin (OP), which structurally contains an epoxide ring, has been majorly isolated from ethyl ...
Javad Mottaghipisheh
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Molecules, 2022 Citrus essential oils are routinely adulterated because of the lack of regulations or reliable authentication methods. Unfortunately, the relatively simple chemical makeup and the tremendous price variations among Citrus varieties encouraged the ...
Noura S. Dosoky +2 more
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<i>Pastinaca sativa</i> L.: Nutritional Composition, Phytochemistry, and Pharmacological Properties Supporting Its Potential as a Functional Food and Therapeutic Agent. [PDF]
Food Sci NutrFood‐grade processing of Pastinaca sativa (parsnip) converts a nutrient‐rich plant matrix (dietary fiber, fructans, phenolics) through washing/slicing/enzymatic treatment and ingredient preparation into functional food ingredients, including fiber concentrates, antioxidant‐rich fractions, and parsnip powders/extracts.
Khatua S +7 more
europepmc +2 more sources
Synthetic biology strategies for the production of furanocoumarins [PDF]
, 2021 [Excerpt] Background: Furanocoumarins are polyphenolic compounds produced in plants as secondary metabolites and with several therapeutic activities. Furanocoumarins such as xanthotoxin and bergapten are known to be used in several severe and difficult
Rodrigues, Joana Lúcia Lima Correia +1 more
core +1 more source
Some Natural Photosensitizers and Their Medicinal Properties for Use in Photodynamic Therapy
Molecules, 2022 Despite significant advances in early diagnosis and treatment, cancer is one of the leading causes of death. Photodynamic therapy (PDT) is a therapy for the treatment of many diseases, including cancer.
Tomasz Piotr Kubrak +5 more
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Exploring Cheminformatic Toolsets for Predicting the Dermal Toxicity of Furanocoumarins [PDF]
, 2021 Linear furanocoumarins are skin sensitizers and anticancer agents whose appeal in skincare therapeutics is widely exploited. Owing to the need to predict the biological activities of medicines, this work aimed the investigate the predicted dermal ...
Thomaz, Douglas Vieira +4 more
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Evaluation of safety profile of the essential oils of eight Heracleum taxa (Apiaceae) related to determined furanocoumarin content [PDF]
Arhiv za farmaciju, 2019 For essential oils of roots, leaves, flowers and fruits of eight Heracleum taxa (H. sphondylium, H. sibiricum, H. montanum, H. ternatum, H. pyrenaicum subsp. pollinianum, H. pyrenaicum subsp. orsinii, H. verticillatum and H.
Ušjak Ljuboš +3 more
doaj +1 more source
Molecules, 2020 Naturally occurring coumarins are bioactive compounds widely used in Asian traditional medicine. They have been shown to inhibit proliferation, induce apoptosis, and/or enhance the cytotoxicity of currently used drugs against a variety of cancer cell ...
Aneta Grabarska +14 more
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