Results 51 to 60 of about 2,649 (197)

Second‐Generation Crystalline Sponges Enabling Consistent Structure Analysis Under Standardized Conditions for Diverse Molecules

Angewandte Chemie, Volume 138, Issue 17, 20 April 2026.
The second‐generation crystalline sponge method allows structurally diverse molecular guests to crystallize under standardized crystallization conditions. The key is the predominant packing type of cages and anions in crystals. ABSTRACT Crystallization is typically highly sensitive to even minor structural differences in target molecules.
Wei He, Hiroki Takezawa, Makoto Fujita
wiley   +2 more sources

Potential Modulation of Phytochemical Bioavailability by Furanocoumarins from Citrus × paradisi

Nutrimentum et Curae
The in vivo efficacy of dietary phytochemicals, known for their antioxidant, anti-inflammatory, and neuroprotective properties, is often limited by poor bioavailability.
Luca Bolognini
doaj   +1 more source

Cytotoxic Activity and Composition of Petroleum Ether Extract from Magydaris tomentosa (Desf.) W. D. J. Koch (Apiaceae)

Molecules, 2015
The petroleum ether extract of Magydaris tomentosa flowers (Desf.) W. D. J. Koch has been analyzed by GC-MS. It is mainly constituted by furanocoumarins such as xanthotoxin, xanthotoxol, isopimpinellin, and bergaptene.
Giuseppina Autore, Stefania Marzocco, Carmen Formisano, Maurizio Bruno, Sergio Rosselli, Mariem Ben Jemia, Felice Senatore   +6 more
doaj   +1 more source

Cobalamin‐Dependent O‐Demethylation of Polymethoxyflavones by Enzymes Isolated From the Human Gut Microorganism Blautia producta MRG‐PMF1

Advanced Synthesis &Catalysis, Volume 368, Issue 16, 18 August 2026.
O‐demethylation of aryl methyl ethers is an invaluable transformation, playing a critical role in ecological circulation by degrading abundant lignin‐derived compounds and other natural products. Chemical O‐demethylation requires harsh reaction conditions; thus, the need for biocatalytic solutions is of high interest.
Niels Krabbe Johnsen, Mykola Franchuk, Freja Elisabeth Wind Rasmussen, Zheng Guo, Jaehong Han, Bekir Engin Eser   +5 more
wiley   +1 more source

Localisation of furanocoumarins in tissues and on the surface of shoots in Heracleum sosnowskyi Manden. [PDF]

, 2017
Heracleum sosnowskyi was introduced in Poland as a fodder plant. Currently, it is regarded as an invasive plant posing a health hazard to humans and animals and a threat to native flora.
Chwil, Mirosława, Weryszko-Chmielewska, Elżbieta, Mirosława Chwil, Elżbieta Weryszko-Chmielewska   +3 more
core   +1 more source

The underappreciated diversity of furanocoumarins in grapefruits revealed by MassQL filtered molecular networking. [PDF]

Food Chem X
Grapefruit is one of the most popular Citrus fruits, which is beneficial for health. Coumarins are the main secondary metabolites in grapefruits. The structural and functional diversity makes the comprehensive determination of coumarins in complex system
Gong S, Bai G, Ban Y, Liu M, Liu Y, Wu Y, Li N, Wu JL.   +7 more
europepmc   +2 more sources

Characterization of Furanocoumarin Profile and Inheritance Toward Selection of Low Furanocoumarin Seedless Grapefruit Cultivars [PDF]

Journal of the American Society for Horticultural Science, 2011
Furanocoumarins are organic chemical components in grapefruit ( Citrus paradisi ) juice that have been shown to induce potentially deleterious drug interactions. In this study we measured seven furanocoumarins (FCs) [bergamottin, 6′,7′-dihydroxybergamottin (6,7-DHB), paradisin C, bergaptol ...
Chunxian Chen, Paul Cancalon, Carl Haun, Fred Gmitter   +3 more
openaire   +1 more source

In Vivo Evaluation of Psoralen in a Copper Sulfate–Induced Chick (Gallus gallus domesticus) Emesis Model and In Silico Analysis of Its Interaction With D2, 5‐HT3A, and Muscarinic Receptors

ChemistryOpen, Volume 15, Issue 8, August 2026.
Psoralen (PSN) demonstrates significant dose‐dependent antiemetic activity in a copper sulfate–induced chick emesis model. Integrated in vivo and in silico analyses reveal reduced retching frequency, prolonged latency, and favorable multi‐receptor interactions with D2, 5‐HT3A, and muscarinic receptors, highlighting PSN as a promising multi‐target ...
Kishor Chandra, Sharif Uddin Bahar, Khadija Akter, Mst Muslima Khatun, Samiran Sadhukhan, Progna Saha Puja, Fazley Rohan, Md Shimul Bhuia, Mohammed Alfaifi, Faisal H. Altemani, Faisal Alsenani, Salehin Sheikh, Muhammad Torequl Islam   +12 more
wiley   +1 more source

Anti-inflammatory activity of prenyl and geranyloxy furanocoumarins from Citrus garrawayi (Rutaceae)

, 2018
Anti-inflammatory activity guided isolation from Citrus garrawayi (Rutaceae) led to the discovery of five new garracoumarins A – E (1 - 5), and five known (6 – 10) isoprenylated furanocoumarins and the known sterol bourjotinolone A (11). Discussed herein
Raju, Ritesh (R17740), Singh, Ahilya (S33030), Muench, Gerald (R12224), Reddell, Paul   +3 more
core   +1 more source

From Molecules to Machines: An Integrative Framework Linking Molecular Pathogenesis, Multi‐Factorial Risk, Risk Stratification, Clinical Management, and Artificial Intelligence in QT Prolongation and Sudden Cardiac Death

Clinical Cardiology, Volume 49, Issue 6, June 2026.
An integrative conceptual framework linking the five principal domains addressed in this review. Beginning at the molecular level, loss‐of‐function mutations in KCNQ1 and KCNH2 reduce outward repolarizing currents (IKs and IKr), while gain‐of‐function SCN5A mutations augment late inward sodium current (INa), establishing the genetic substrate for ...
Mojtaba Farjam, Mohammad Hosein Yazdanpanah, Narges Fereydouni   +2 more
wiley   +1 more source