Results 61 to 70 of about 2,649 (197)

Pharmacokinetic Evaluation of a Cinnamon Product on CYP2A6 Substrate Drugs: Application of a Novel Tool Involving the Nicotine Metabolite Ratio

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1485-1493, June 2026.
Cinnamon (Cinnamomum spp.) is used as a culinary spice and dietary supplement. A major constituent, cinnamaldehyde, was previously shown to inactivate cytochrome P450 (CYP) 2A6 in vitro. A mechanistic static model predicted an ~5‐fold increase in the AUC of the CYP2A6 substrates nicotine and letrozole.
Aiden‐Hung P. Nguyen   +8 more
wiley   +1 more source

Pharmacological and Phytochemical Insights Into Ficus benghalensis (Indian Banyan): Anti‐Inflammatory, Antioxidant, and Anticancer Potentials

open access: yesFood Science &Nutrition, Volume 14, Issue 6, June 2026.
The aim of this review is to critically evaluate the therapeutic potential of Ficus benghalensis L. by integrating ethnomedicinal knowledge with contemporary scientific evidence. The objectives are to summarize its phytochemical profile, analyze antioxidant, antimicrobial, antidiabetic, anti‐inflammatory, and anticancer activities, elucidate underlying
Zainab Ali   +9 more
wiley   +1 more source

Elicitation of furanocoumarins in poison hemlock (Conium maculatum L.) cell culture

open access: yes, 2015
Furanocoumarins, such as psoralen, xanthotoxin and bergapten, serve as protectants against phytopathogens and are used in pharmaceutical applications e.g. as DNA-crosslinking agents against non-melanoma skin cancers.
Hotti, Hannu; id_orcid   +2 more
core   +1 more source

Changes of furanocoumarins content in vegetables during storage

open access: yesCzech Journal of Food Sciences, 2004
Long term experiments, which simulated storage of celery (Apium graveolens) under industrial (airconditioned store)/household (common cellar) conditions, were carried out.
P. Botek   +3 more
doaj   +1 more source

Furanocoumarins on the surface of callus cultures from species of the Rutaceae and Umbelliferae

open access: yes, 1993
Four linear furanocoumarins (psoralen, xanthotoxin, isopimpinellin, and bergapten) were identified on the surfaces of callus cells of Ruta graveolens, Ruta pinnata, Daucus carota, and Pastinaca sativa in the concentration range of 0.055 – 1.1 μg total/g
Stewart A. Brown, Alicja M. Zobel
core   +1 more source

Ruta chalepensis L. In Vitro Cultures as a Source of Bioactive Furanocoumarins and Furoquinoline Alkaloids

open access: yes, 2023
Recently, due to the decreasing areas of cultivation and climate change, the use of biotechnological methods to obtain biomass, which is a source of valuable bioactive metabolites, is becoming more and more interesting. In this study, Ruta chalepensis in
Dominika Zych   +5 more
core   +1 more source

A Super‐Pangenome for Cultivated Citrus Reveals Evolutive Features During the Allopatric Phase of Their Reticulate Evolution

open access: yesPlant Biotechnology Journal, Volume 24, Issue 5, Page 3345-3367, May 2026.
Structure of the cultivated citrus super‐pangenome. ABSTRACT The main genetic diversity observed in cultivated citrus results from a reticulate evolution involving four ancestral taxa whose radiation occurred in allopatry. In such context, GWAS analysis, genome diversity and transcriptomic studies will be significantly enhanced through pangenome ...
Gaetan Droc   +27 more
wiley   +1 more source

Influence of fertilisation on furanocoumarins content in two celeriac varieties

open access: yes, 2008
The aim of this study was to investigate the effect of the way of celeriac cultivation on the content of naturally occurring toxicants - furanocoumarins. Their levels have been shown to be strongly affected by an individual variety and also fertilization
Schulzova, Vera   +5 more
core   +1 more source

Furanocoumarins from the aerial parts of Dorstenia contrajerva

open access: yes, 2001
: A new glycosylated furanocoumarin, α-l-rhamnopyranosyl-(1→6)-β-d-glucopyranosyl-bergaptol (1), has been isolated from Dorsteniacontrajerva together with three known furanocoumarins, catechin and epicatechin. Their structures were established using high
DE MARTINO, Giovanni   +11 more
core   +1 more source

Apoptosis kinetics of purified and PBMC‐associated lymphocytes after photopheresis‐like 8‐methoxypsolaren/UVA treatment

open access: yesPhotochemistry and Photobiology, Volume 102, Issue 3, Page 732-745, May/June 2026.
Extracorporeal photopheresis (ECP) induces apoptosis in circulating immune cells, but its kinetics vary slightly depending on the cell type. We compared the progression of apoptosis in PBMCs versus highly purified T cells exposed to 8‐methoxypsoralen and ultraviolet A.
Carlos Agustin Villegas‐Valverde   +6 more
wiley   +1 more source

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